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Muscles and connective tissue
Systemic sclerosis (scleroderma)
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Publications and studies (2095)
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Growth Disturbances in Children With Rheumatologic Diseases. (2026/04/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A new approach and conceptual model for understanding systemic sclerosis-associated gastrointestinal symptoms. (2026/04/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Evolving landscape of imaging-based evaluation in systemic autoimmune rheumatic disease-associated interstitial lung disease: from visual assessment to quantitative artificial intelligence-assisted evaluation. (2026/04/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Effect of Probiotic and Synbiotic Oral Supplementation in Autoimmune Diseases: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. (2026/03/30) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pregnancy outcomes in systemic sclerosis before and after diagnosis: a retrospective nationwide cohort study. (2026/03/30) ♡
- Mapping neurogenic dysphagia diagnostics in Germany: accessibility, implementation practices, and barriers to swallowing endoscopy. (2026/03/18) ♡
- The Association between Eye Sign and Capillaroscopy Changes in Patients with Scleroderma Spectrum Disease Presenting with Raynaud's Phenomenon, as Compared to the Normal Population. (2026/03/18) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Severe scleroderma colopathy at initial diagnosis of systemic sclerosis in a young man: a case report. (2026/03/12) ♡
- Prevention and management of gastrointestinal side effects in patients with systemic sclerosis-interstitial lung disease receiving anti-fibrotic therapy: a modified Delphi consensus study. (2026/03/10) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Resting Oxygen Consumption Estimates in Scleroderma Can Lead to Underestimation of Cardiac Output. (2026/03/10) ♡
- The Th17/Treg axis: a key to understanding and treating autoimmune disorders. (2026/03/05) ♡
- Atorvastatin alleviates the progression of fibrosis in experimental systemic sclerosis: Binding to macrophage CD14 to regulate TLR4/p65 or directly modulating fibroblast Smad3 signaling. (2026/03/01) ♡
- Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging-Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases. (2026/03/01) ♡
- Nailfold videocapillaroscopy in the assessment of juvenile connective tissue diseases. (2026/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nutraceutical interventions for neuroprotection: a comprehensive review. (2026/03/01) ♡
- Deficiency of inducible nitric oxide synthase alleviates dermal fibrosis and inflammation in scleroderma. (2026/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Obesity, Nutrition and the Multiple Sclerosis Risk in Adolescents. (2026/02/28) ♡
- Targeting low-grade inflammation in multiple sclerosis through the Wim Hof method or lifestyle intervention: a pilot comparative study. (2026/02/26) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Impact of the Combination of Epigallocatechin Gallate and Ellagic Acid Supplemented with Ketone Bodies on Energetic Restoration of Mitochondrial Dysfunction and Metabolic Inefficiencies in Patients with Multiple Sclerosis: A Review. (2026/02/25) ♡
- Case of generalized morphea complicated with systemic sclerosis. (2026/02/12) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Micronutrients in Autoimmune Diseases: Shining a Light on Vitamin D, Cobalamin, Folate, and Iron Metabolism. (2026/02/08) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. The Effects of Microbiome Modulating Therapies on Inflammatory Markers in Autoimmune Disease: A Systematic Review and Meta-Analysis. (2026/02/08) ♡
- Reduced retinal microvascular density in patients with mixed connective tissue disease: an exploratory pilot study on the interplay between aging, renal function, and complement system. (2026/02/05) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Gut Microbiota: Emerging Evidence in Autoimmune and Inflammatory Diseases. (2026/02/04) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Silent Burden of Urinary Tract Infections in Intermittent Catheter Users with Neurological Disorders: A Scoping Review. (2026/02/03) ♡
- HERC5, IFI6, IFIT3, and OASL as potential diagnostic biomarkers for systemic lupus erythematosus: an integrated bioinformatics, machine learning and clinical validation. (2026/02/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Hand function impairment in Systemic Sclerosis: determinants through investigations of clinical, radiographic and ultrasonographic features. (2026/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Histological and molecular study of the ameliorative effects of silymarin on skeletal muscle changes in cuprizone-induced multiple sclerosis in mice. (2026/02/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. The effect of dietary interventions on peripheral markers of inflammation among people with multiple sclerosis: A systematic review and meta-analysis of randomized controlled trials. (2026/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Is a Functional Cure Possible in Autoimmune Diseases? Evidence from Trigger Eradication, Transplantation, and Cellular Therapies. (2026/02/01) ♡
- Ultrasonographic Measurements of Tongue Thickness and Swallowing Dysfunction in Amyotrophic Lateral Sclerosis: A Feasibility Study. (2026/02/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. From inhibition to regulation: serpins in health and disease. (2026/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Targeting gut-brain-immune axis in amyotrophic lateral sclerosis. (2026/01/29) ♡
- Cross-disease transcriptomic meta-analysis and network pharmacology reveal key therapeutic targets in rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis. (2026/01/21) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Systemic Sclerosis-Related Intestinal Pseudo-Obstruction Mimicking Mechanical Small Bowel Obstruction. (2026/01/18) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Genetic and Genomic Analysis of Systemic Sclerosis: A Narrative Review of the Recent Advancement. (2026/01/15) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Integrin alpha L: structure, cellular functions, and emerging role in human diseases. (2026/01/12) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Engineering neuroimmune regulation: biomaterial and nanotechnology platforms for neuropathology diagnosis and targeted immunomodulation. (2026/01/09) ♡
- Right ventricular myocardial performance index as an early marker of cardiac dysfunction in systemic sclerosis. (2026/01/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Brain-derived extracellular vesicles potentially mediate crosstalk with peripheral organs in neurodegenerative diseases. (2026/01/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Role of Vitamin D in Autoimmune Diseases. (2026/01/05) ♡
- Underrepresentation of Black participants in systemic sclerosis clinical trials: the U.S.A. and southeast region. (2026/01/01) ♡
- Integration of natural language models in the diagnosis of systemic autoimmune diseases: validation of GPT-4 in a tertiary care center. (2026/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Biosensors for detection of autoimmune disease. (2026/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Vitamin D and Autoimmunity. (2026/01/01) ♡
- Prevalence of malnutrition using the GLIM criteria and the subjective global assessment among patients with rheumatic and musculoskeletal diseases. (2026/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Association of Individual or Family History of Autoimmune Disease With Future Development of Type 1 Diabetes. (2026/01/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Scleroderma Renal Crisis and Posterior Reversible Encephalopathy Syndrome Triggered by Non-steroidal Anti-inflammatory Drugs. (2026/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research (2026-08-10) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease (2026-08-07) ♡
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