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Systemic sclerosis (scleroderma)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (63)Meta-analysis (20)Treatment guideline (3)Systematic review (23)Randomized trial (11)Phase 3 study (6)Clinical trial (613)Review article (412)Early study (phase 1 or 2) (29)Case report (177)Laboratory or animal study (26)Commentary or editorial (42)Retracted publication (2) Studies currently recruiting participants only (39)

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Publications and studies (2095)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Muscular Respiratory Involvement and Systemic Sclerosis (2021-09-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Oral Manifestations of Systemic Sclerosis (2021-09-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Safety of PLACENTEX ® i.m. in Patients With Scleroderma Diseases (2021-09-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Endothelial Biomarkers of Systemic Sclerosis-associated Pulmonary Hypertension (2021-09-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. New Orleans Pulmonary Hypertension Biobank (2021-09-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ILD-SARDs Registry and Biorepository (2021-09-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Assess Sarilumab in Halting Progression of Morphea (2021-09-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Volatile Organic Compounds (VOCs) as a Biomarker in Immune-mediated Pulmonary Arterial Hypertension (PAH) (2021-09-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The SPIN - Scleroderma Support Group Leader EDucation Program Trial (SPIN-SSLED) (2021-08-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis (2021-08-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pulmonary Hypertension Screening for Rheumatology Patients (SOPHIE) (2021-08-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prednisolone in Early Diffuse Systemic Sclerosis (2021-07-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Scleroderma Patient-centered Intervention Network (SPIN) Hand Program Feasibility Study (2021-07-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases (2021-07-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy (2021-07-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Tolerability of STI571 (Imatinib Mesylate) for the Treatment of Fibrosis in Participants With Systemic Sclerosis (2021-07-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Safety of Rifaximin for Patients With Chronic Intestinal Pseudo-obstruction: a Phase 2 Trial (2021-06-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic Sclerosis (2021-06-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis (2021-05-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Systemic Sclerosis (2021-05-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Effects of Botulinum Toxin on Oral Aperture in Patients With Scleroderma (2021-04-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mindfulness Based Stress Reduction in Rheumatic Diseases (2021-04-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Smartphone Mindfulness Meditation for Patients With Rheumatic Diseases (2021-04-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Immunomodulating Effects of Supplementation With 25-OH Vitamin D (2021-04-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety, Tolerability, Efficacy, and Pharmacokinetics of JBT-101 in Systemic Sclerosis (2021-04-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effects of a Supervised Exercise Program and a Home Exercise Program in Patients With Systemic Sclerosis (2021-04-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Systemic Sclerosis (SSc) Vasculopathy: Improved Clinical Monitoring and Treatment (2021-04-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Endothelial Function in Patients With Scleroderma or Cirrhosis With and Without Pulmonary Hypertension (2021-04-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pilot Study Evaluating the Efficacy of a Topical PDE4 Inhibitor for Morphea (2021-04-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis (2021-03-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pain Outcomes Following Intralesional Corticosteroid Injections (2021-03-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Autologous Fat Grafting in the Treatment of Critical Limb Ischaemia (2021-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome (2021-02-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Duke Scleroderma Clinic Patient Registry (2021-01-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Effect of Physiotherapy Program in Scleroderma Patients (2021-01-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble Swallowing (2021-01-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Ambrisentan for the Improvement in Right Ventricular Strain in Scleroderma Associated Pulmonary Arterial Hypertension (2021-01-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Hyaluronidase in Treating Oral Microstomia in Patients With Sclerosing Skin Disease (2021-01-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Role of Macrophage Migratory Inhibitory Factor in Systemic Sclerosis (2021-01-12) ♡
• Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5. (2020/12/30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of the Correlation between HRCT Semi-quantitative Scoring, Concentration of Alveolar Nitric Oxide, and Clinical-functional Parameters of Systemic Sclerosis-induced Interstitial Lung Disease. (2020/12/29) ♡
• Air pollutants and development of interstitial lung disease in patients with connective tissue disease: a population-based case-control study in Taiwan. (2020/12/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathological Insight into 5-HT(2B) Receptor Activation in Fibrosing Interstitial Lung Diseases. (2020/12/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Treatment Targets for Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. (2020/12/28) ♡
• Searching for Possible Links between Alzheimer's Disease and Systemic Sclerosis. (2020/12/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Intestinal Microbes in Autoimmune and Inflammatory Disease. (2020/12/23) ♡
• MiR-16-5p suppresses myofibroblast activation in systemic sclerosis by inhibiting NOTCH signaling. (2020/12/19) ♡
• Clinical Outcomes of Myocarditis after Moderate-Dose Steroid Therapy in Systemic Sclerosis: A Pilot Study. (2020/12/19) ♡
• Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. Connective tissue disease-related interstitial lung disease (CTD-ILD) and interstitial lung abnormality (ILA): Evolving concept of CT findings, pathology and management. (2020/12/16) ♡
• Shared development of targeted therapies among autoimmune and inflammatory diseases: a systematic repurposing analysis. (2020/12/16) ♡

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