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Muscles and connective tissue
Systemic sclerosis (scleroderma)
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Publications and studies (2095)
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma (2025-02-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma (2025-02-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study on the Treatment With Water-filtered Infrared-A (wIRA) Radiation in Patients With Morphea and Sclerotic Graft-versus-host Disease (2025-01-30) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease (2025-01-17) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Ultrasound and Electrophysiology Study of Hand in Systemic Sclerosis Patients and Contributors of Hand Dysfunction (2025-01-15) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases (2025-01-10) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Relationship Between Pelvic Floor Dysfunctions and Sexual Dysfunction in Female Patients with Systemic Sclerosis (2025-01-10) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Scleroderma Treatment With Autologous Transplant (STAT) Study (2025-01-07) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Use of Selective JAK Inhibitor in ILD and Skin Tightness of Systemic Sclerosis Versus MMF (2025-01-06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Use of platelet-rich plasma in rheumatic diseases. (2024/12/31) ♡
- Evaluation of IRF7 mRNA and its Association with Promoter Methylation in Kashmiri (North-Indian) Patients with Systemic Sclerosis: A Case-Control Study. (2024/12/31) ♡
- Pilot Study of Diagnostic Performances of Vascular Biomarkers Soluble fms-Like Tyrosine Kinase and Placental Growth Factor in Scleroderma Renal Crisis. (2024/12/31) ♡
- Association of uveitis with pediatric autoimmune diseases based on a TriNetX study. (2024/12/30) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nutritional and Microbiota-Based Approaches in Amyotrophic Lateral Sclerosis: From Prevention to Treatment. (2024/12/30) ♡
- Citric acid is more effective than sodium thiosulfate in chelating calcium in a dissolution model of calcinosis. (2024/12/28) ♡
- The density histograms-derived computerized integrated index (CII) predicts mortality in idiopathic pulmonary fibrosis. (2024/12/28) ♡
- Lack of association of the PLD4 SNP rs2841277 with systemic sclerosis in a European American population. (2024/12/28) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Multimodal Screening for Pulmonary Arterial Hypertension in Systemic Scleroderma: Current Methods and Future Directions. (2024/12/27) ♡
- The effects of coagulation factors on the risk of autoimmune diseases: A Mendelian randomization study. (2024/12/27) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pinhole Descending Aortic Rupture with Systemic Sclerosis and Dermatomyositis: A Case Report. (2024/12/25) ♡
- Exploring the Genetic Association Between Connective Tissue Diseases and the Risk of Pulmonary Arterial Hypertension: A Mendelian Randomization Analysis. (2024/12/24) ♡
- Meeting Report on "10th Anniversary Symposium on Inflammatory Skin Disease". (2024/12/24) ♡
- ADAM Metallopeptidase domain 19 promotes skin fibrosis in systemic sclerosis via neuregulin-1. (2024/12/23) ♡
- Evaluating the role of active TGF-β1 as inflammatory biomarker in Kashmiri (North-Indian) patients with systemic sclerosis: a case-control study. (2024/12/23) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rationale for phosphodiesterase-4 inhibition as a treatment strategy for interstitial lung diseases associated with rheumatic diseases. (2024/12/23) ♡
- The Efficacy and Tolerability of Prostaglandin Analogues in Treating Systemic Sclerosis-Associated Raynaud Phenomenon: A Systematic Review and Meta-Analysis. (2024/12/23) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Endostatin as a biomarker of systemic sclerosis: insights from a systematic review and meta-analysis. (2024/12/23) ♡
- Macrophages Contribute to Cardiac Fibrosis and Diastolic Dysfunction in Systemic Sclerosis. (2024/12/23) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Atypical Presentation of Optic Neuritis in Multiple Sclerosis. (2024/12/21) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. The Therapeutic Potential of Oral Everolimus for Facial Angiofibromas in Pediatric Tuberous Sclerosis Complex: A Case-Based Analysis of Efficacy. (2024/12/20) ♡
- A Scleroderma and Raynaud's UK (SRUK) national survey to explore rheumatologists' awareness, approaches to diagnosis and management and training needs within systemic sclerosis. (2024/12/20) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Clinical Characteristics and Management of Oral Candidiasis Associated with Calcinosis, Raynaud's Phenomenon, Esophageal Dysmotility, Sclerodactyly, and Telangiectasia Syndrome. (2024/12/20) ♡
- Quantitative (18)F-FDG PET-CT can assess presence and extent of interstitial lung disease in early severe diffuse cutaneous systemic sclerosis. (2024/12/19) ♡
- Non-Invasive Cardiac and Vascular Monitoring in Systemic Sclerosis: Impact of Therapy on Subclinical Dysfunction. (2024/12/19) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Expression and significance of ferroptosis marker 4-HNE in in vitro model of systemic sclerosis]. (2024/12/18) ♡
- [COVID-19 vaccines efficacy and infection features in patients with systemic sclerosis: A single-center cohort study]. (2024/12/18) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Dorsoventral photobiomodulation therapy safely reduces inflammation and sensorimotor deficits in a mouse model of multiple sclerosis. (2024/12/18) ♡
- Unveiling the shared genes between systemic sclerosis and lung cancer. (2024/12/18) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. CD19 CAR-T cell therapy: a new dawn for autoimmune rheumatic diseases? (2024/12/17) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Bifidobacterium longum RAPO Attenuates Dermal and Pulmonary Fibrosis in a Mouse Model of Systemic Sclerosis through Macrophage Modulation and Growth of Short-Chain Fatty Acid Producers. (2024/12/17) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. C3 deficiency promotes pulmonary inflammation in AT1R-induced mouse model for systemic sclerosis. (2024/12/16) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Cellular therapies in rheumatic and musculoskeletal diseases. (2024/12/16) ♡
- Neuro-Behçet's Disease Masquerading as Multiple Sclerosis in a Young Male. (2024/12/15) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Case report: Systemic sclerosis during neoadjuvant therapy for breast cancer in a 59-year-old woman. (2024/12/13) ♡
- Tuberous sclerosis: a survey in the canton of Vaud, Switzerland. (2024/12/12) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The advent of chimeric antigen receptor T Cell therapy in recalibrating immune balance for rheumatic autoimmune disease treatment. (2024/12/12) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exploring New and Potential Indications for Botulinum Toxin Treatment: An Updated Literature Review. (2024/12/11) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Effects of Probiotics on Neurodegenerative Disease-Related Symptoms and Systemic Inflammation: A Systematic Review. (2024/12/10) ♡
- Severe Spinal Stenosis Secondary to a CREST Syndrome Related Calcific Deposit: A Case Report. (2024/12/10) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Vitamin, antioxidant and micronutrient supplementation and the risk of developing incident autoimmune diseases: a systematic review and meta-analysis. (2024/12/09) ♡
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