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Primary lateral sclerosis
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Publications and studies (2508)
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Oral health status of hospitalized amyotrophic lateral sclerosis patients: a single-centre observational study. (2018/05/01) ♡
- Subthalamic deep brain stimulation and trunk posture in Parkinson's disease. (2018/05/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Spinal motor neuron involvement in a patient with homozygous PRUNE mutation. (2018/05/01) ♡
- Best practices protocol for the evaluation of bulbar dysfunction: summary recommendations from the NEALS bulbar subcommittee symposium. (2018/05/01) ♡
- Dysregulation of microRNA biogenesis machinery and microRNA/RNA ratio in skeletal muscle of amyotrophic lateral sclerosis mice. (2018/05/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Hydration measured by doubly labeled water in ALS and its effects on survival. (2018/05/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Amyotrophic lateral sclerosis and food intake. (2018/05/01) ♡
- Pre-diagnostic plasma urate and the risk of amyotrophic lateral sclerosis. (2018/05/01) ♡
- Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice. (2018/05/01) ♡
- Exhaustively Characterizing a Patient Cohort by Prevalence of EMR Facts: a Generalized, Vendor-Agnostic Method for Quality Control and Research. (2018/04/16) ♡
- Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice. (2018/04/11) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Novel BICD2 mutation in a Japanese family with autosomal dominant lower extremity-predominant spinal muscular atrophy-2. (2018/04/01) ♡
- ATXN1 intermediate-length polyglutamine expansions are associated with amyotrophic lateral sclerosis. (2018/04/01) ♡
- Abnormal cortical brain integration of somatosensory afferents in ALS. (2018/04/01) ♡
- High frequency of C9orf72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis patients from two founder populations sharing the same risk haplotype. (2018/04/01) ♡
- Mutation analysis of the TIA1 gene in Chinese patients with amyotrophic lateral sclerosis and frontotemporal dementia. (2018/04/01) ♡
- Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic amyotrophic lateral sclerosis. (2018/04/01) ♡
- Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis. (2018/04/01) ♡
- Riluzole and other prognostic factors in ALS: a population-based registry study in Italy. (2018/04/01) ♡
- Influence of a multidisciplinary protocol on nutritional status at diagnosis in amyotrophic lateral sclerosis. (2018/04/01) ♡
- Nasal unsedated seated percutaneous endoscopic gastrostomy (nuPEG): a safe and effective technique for percutaneous endoscopic gastrostomy placement in high-risk candidates. (2018/04/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. What is causing this patient's bilateral leg weakness? (2018/04/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. ASAH1-Related Disorders. (2018/03/29) ♡
- IGF1 affects macrophage invasion and activation and TNF-α production in the sciatic nerves of female SOD1G93A mice. (2018/03/06) ♡
- Patients with sporadic and familial amyotrophic lateral sclerosis found value in genetic testing. (2018/03/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility. (2018/03/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Slowing disease progression in the SOD1 mouse model of ALS by blocking neuregulin-induced microglial activation. (2018/03/01) ♡
- Risk factors in Swedish young men for amyotrophic lateral sclerosis in adulthood. (2018/03/01) ♡
- A missense mutation in DYNC1H1 gene causing spinal muscular atrophy - Lower extremity, dominant. (2018/03/01) ♡
- Liver X Receptor Genes Variants Modulate ALS Phenotype. (2018/03/01) ♡
- Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics. (2018/03/01) ♡
- Percutaneous endoscopic gastrostomy with and without jejunal extension in patients with amyotrophic lateral sclerosis. (2018/03/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Editorial. (2018/03/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. The First Report of a Japanese Case of Seipinopathy with a BSCL2 N88S Mutation. (2018/02/15) ♡
- Immunohistochemistry and electrophysiological findings in swine abattoir workers with immune-mediated polyradiculoneuropathy. (2018/02/15) ♡
- Lack of an association between attention-deficit/hyperactivity disorder (ADHD) and amyotrophic lateral sclerosis (ALS). (2018/02/15) ♡
- The developmental and genetic basis of 'clubfoot' in the peroneal muscular atrophy mutant mouse. (2018/02/08) ♡
- Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis. (2018/02/01) ♡
- Correlations between MUNIX and adapted multiple point stimulation MUNE methods. (2018/02/01) ♡
- Fasciculation potentials and decremental responses in amyotrophic lateral sclerosis. (2018/02/01) ♡
- Diaphragm motor responses to phrenic nerve stimulation in ALS: Surface and needle recordings. (2018/02/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Fasciculation: Does distance really matter? (2018/02/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Case series: Slowing alpha rhythm in late-stage ALS patients. (2018/02/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pre-emptive awake airway management under dexmedetomidine sedation in a parturient with spinal muscular atrophy type-2. (2018/02/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Distal myopathy due to BICD2 mutations. (2018/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Simvastatin inhibits the apoptosis of hippocampal cells in a mouse model of Alzheimer's disease. (2018/02/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Nutrition management methods effective in increasing weight, survival time and functional status in ALS patients: a systematic review. (2018/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neuromuscular diseases: Diagnosis and management. (2018/02/01) ♡
- Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. Diagnosis and management of spinal muscular atrophy: Part 1: Recommendations for diagnosis, rehabilitation, orthopedic and nutritional care. (2018/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Possible etiology and treatment of amyotrophic lateral sclerosis. (2018/02/01) ♡
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