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Primary lateral sclerosis

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (123)Meta-analysis (29)Treatment guideline (6)Systematic review (51)Randomized controlled trial (19)Phase 3 study (18)Clinical trial (658)Review article (336)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (123)Case description (120)Commentary or editorial (46)Retracted publication (1) Studies currently recruiting participants only (31)

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Publications and studies (2508)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Novel challenges in spinal muscular atrophy - How to screen and whom to treat? (2018/11/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development. (2018/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neurotoxicity of Prosopis juliflora: from Natural Poisoning to Mechanism of Action of Its Piperidine Alkaloids. (2018/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Phenotypic heterogeneity of astrocytes in motor neuron disease. (2018/11/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. 3-Iodothyronamine Acting through an Anti-Apoptotic Mechanism Is Neuroprotective Against Spinal Cord Injury in Rats. (2018/11/01) ♡
• Relationship of statins and other cholesterol-lowering medications and risk of amyotrophic lateral sclerosis in the US elderly. (2018/11/01) ♡
• Pilot trial of inosine to elevate urate levels in amyotrophic lateral sclerosis. (2018/10/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Nutritional management of amyotrophic lateral sclerosis: summary of recommendations]. (2018/10/08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Nusinersen in patients older than 7 months with spinal muscular atrophy type 1: A cohort study. (2018/10/02) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A new splice-site mutation in SLC12A6 causing Andermann syndrome with motor neuronopathy. (2018/10/01) ♡
• Individual treatment effect prediction for amyotrophic lateral sclerosis patients. (2018/10/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. A Systematic Review and Meta-Analysis on Outcomes and Complications of Percutaneous Endoscopic Versus Radiologic Gastrostomy for Enteral Feeding. (2018/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ketogenic Diets for Adult Neurological Disorders. (2018/10/01) ♡
• Amyotrophic Lateral Sclerosis and soccer: an internet survey of 29 Italian players. (2018/10/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Curious Case of Ankylosing Spondylosis and Motor Neuron Disease: A Mere Coincidence or Correlation? (2018/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. TARDBP mutation associated with semantic variant primary progressive aphasia, case report and review of the literature. (2018/10/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Riboflavin Treatment in Genetically Proven Brown-Vialetto-Van Laere Syndrome. (2018/10/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Nusinersen for SMA: expanded access programme. (2018/09/01) ♡
• Acteoside protects against 6-OHDA-induced dopaminergic neuron damage via Nrf2-ARE signaling pathway. (2018/09/01) ♡
• Prevalence of metabolic syndrome and non-alcoholic fatty liver disease in a cohort of italian patients with spinal-bulbar muscular atrophy. (2018/09/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. MULTIFOCAL MOTOR NEUROPATHY: CASE REPORTS. (2018/09/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. An observational study of functional abilities in infants, children, and adults with type 1 SMA. (2018/08/21) ♡
• Feasibility of Automatic Error Detect-and-Undo System in Human Intracortical Brain-Computer Interfaces. (2018/08/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prediagnostic body size and risk of amyotrophic lateral sclerosis death in 10 studies. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The increasing importance of environmental conditions in amyotrophic lateral sclerosis. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Muscle Overactivity in the Upper Motor Neuron Syndrome: Pathophysiology. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Meaningful Assessment in Patients with Acquired Brain Injuries. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Special Considerations in Pediatric Assessment. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Muscle Overactivity in the Upper Motor Neuron Syndrome: Conceptualizing a Treatment Plan and Establishing Meaningful Goals. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pharmacologic Treatment Tools: Systemic Medications and Toxins, Opportunities, and Pitfalls. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Muscle Overactivity in the Upper Motor Neuron Syndrome: Assessment and Problem Solving for Complex Cases: the Role of Physical and Occupational Therapy. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Intrathecal Therapies. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Neuro-Orthopaedic Approach. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Upper Extremity Problem-Solving: Challenging Cases. (2018/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Lower Extremity Problem-Solving: Challenging Cases. (2018/08/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Muscle Over-Activity in Upper Motor Neuron Syndrome: Assessment and Problem Solving for Complex Cases. (2018/08/01) ♡
• Interplay between spinal cord and cerebral cortex metabolism in amyotrophic lateral sclerosis. (2018/08/01) ♡
• Motor neuron biology and disease: A current perspective on infantile-onset spinal muscular atrophy. (2018/08/01) ♡
• Preliminary Observation about Alteration of Proteins and Their Potential Functions in Spinal Cord of SOD1 G93A Transgenic Mice. (2018/07/27) ♡
• Globular Glial Tauopathy May be Mistaken for Corticobasal Syndrome-Pointers for the Clinician. (2018/07/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Genetic, Radiologic, and Clinical Variability in Brown-Vialetto-van Laere Syndrome. (2018/07/01) ♡
• Advance care planning for patients with advanced neurology diseases. (2018/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Supportive & palliative interventions in motor neurone disease: what we know from current literature? (2018/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. The First Case of Riboflavin Transporter Deficiency in sub-Saharan Africa. (2018/07/01) ♡
• Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1(G93A) Transgenic Mice. (2018/06/25) ♡
• Pilot study of population-based newborn screening for spinal muscular atrophy in New York state. (2018/06/01) ♡
• hmSOD1 gene mutation-induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway. (2018/06/01) ♡
• Comprehensive nutritional and metabolic assessment in patients with spinal muscular atrophy: Opportunity for an individualized approach. (2018/06/01) ♡
• Neuroprotective effect of Da Chuanxiong Formula against cognitive and motor deficits in a rat controlled cortical impact model of traumatic brain injury. (2018/05/10) ♡
• Assessing amyotrophic lateral sclerosis prevalence in Norway from 2009 to 2015 from compulsory nationwide health registers. (2018/05/01) ♡

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