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Primary lateral sclerosis
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Publications and studies (2510)
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. An Overview Of The Management And Rehabilitation Of Dysphagia. (2023/08/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Assessing causal relationship between circulating cytokines and age-related neurodegenerative diseases: a bidirectional two-sample Mendelian randomization analysis. (2023/07/29) ♡
- Protective Effects of Polyphenol-Rich Extracts against Neurotoxicity Elicited by Paraquat or Rotenone in Cellular Models of Parkinson's Disease. (2023/07/20) ♡
- A Diagnostic Gene-Expression Signature in Fibroblasts of Amyotrophic Lateral Sclerosis. (2023/07/18) ♡
- Quality appraisal of clinical practice guidelines for motor neuron diseases or related disorders using the AGREE II instrument. (2023/07/17) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial. (2023/07/10) ♡
- Different Tendencies in Muscle Ultrasound Characteristic in Amyotrophic Lateral Sclerosis and Chronic Inflammatory Demyelinating Polyradiculoneuropathy. (2023/07/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. The role of nutrition on Parkinson's disease: a systematic review. (2023/07/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Translating fatigability in spinal muscular atrophy to clinical trials and management. (2023/07/01) ♡
- Plasma levels of soluble RAGE, AGEs and AOPPs at the early stage of amyotrophic lateral sclerosis: A preliminary study. (2023/07/01) ♡
- Guideline "Motor neuron diseases" of the German Society of Neurology (Deutsche Gesellschaft für Neurologie). (2023/06/15) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Editorial: Strategies to fight exercise intolerance in neuromuscular disorders, volume II. (2023/06/07) ♡
- Amyotrophic lateral sclerosis with respiratory failure and dysautonomia: a case report. (2023/06/07) ♡
- Patient, carer and healthcare professional perspectives on increasing calorie intake in Amyotrophic Lateral Sclerosis. (2023/06/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice. (2023/06/01) ♡
- Clinical relevance of macroglossia to disease progression in ventilation dependent patients with advanced ALS. (2023/06/01) ♡
- Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: outcomes of a dedicated anesthesia and surgery protocol. (2023/06/01) ♡
- Association of blood lipids with onset and prognosis of amyotrophic lateral sclerosis: results from the ALS Swabia registry. (2023/06/01) ♡
- Type I spinal muscular atrophy patients treated with nusinersen: 4-year follow-up of motor, respiratory and bulbar function. (2023/06/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation. (2023/06/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Ketogenic diet protects MPTP-induced mouse model of Parkinson's disease via altering gut microbiota and metabolites. (2023/05/16) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. MGMT, a risk factor for both genetic and environmental forms of dementia. (2023/05/01) ♡
- Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood. (2023/05/01) ♡
- Yield of EEG features as markers of disease severity in amyotrophic lateral sclerosis: a pilot study. (2023/05/01) ♡
- Prognostic Value of Regular Nutritional Treatment in Patients With Amyotrophic Lateral Sclerosis. (2023/05/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Alternative medicine therapies in neurological disorders: Prevalence, reasons and associated factors. A systematic review. (2023/05/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Malnutrition assessment by Global Leadership Initiative on Malnutrition criteria in patients with amyotrophic lateral sclerosis. (2023/05/01) ♡
- Aspiration Prevention Surgery: Clinical Factors Associated With Improvements in Oral Status Intake and Suction Frequency. (2023/05/01) ♡
- Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease. (2023/04/27) ♡
- Integrated Omic Analysis Delineates Pathways Modulating Toxic TDP-43 Protein Aggregates in Amyotrophic Lateral Sclerosis. (2023/04/24) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Combined Tui na and Western medicine treatment improves pulmonary function and quality of life in patients with amyotrophic lateral sclerosis: A case report. (2023/04/21) ♡
- Deregulation of Plasma microRNA Expression in a TARDBP-ALS Family. (2023/04/21) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Bulbar Onset Amyotrophic Lateral Sclerosis in a COVID-19 Patient: A Case Report. (2023/04/19) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Mutant and curli-producing E. coli enhance the disease phenotype in a hSOD1-G93A mouse model of ALS. (2023/04/12) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A Glutamate Scavenging Protocol Combined with Deanna Protocol in SOD1-G93A Mouse Model of ALS. (2023/04/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanical ventilation in dogs and cats with tick paralysis. (2023/04/06) ♡
- Clinimetrics of the cognitive section of the Italian ALS Cognitive Behavioral Screen (ALS-CBS™). (2023/04/01) ♡
- Maximum lingual pressure impacts both swallowing safety and efficiency in individuals with amyotrophic lateral sclerosis. (2023/04/01) ♡
- Genetic correlation and gene-based pleiotropy analysis for four major neurodegenerative diseases with summary statistics. (2023/04/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. The level of homocysteine in amyotrophic lateral sclerosis: a systematic review and meta-analysis. (2023/04/01) ♡
- A breakthrough effect of gene replacement therapy on respiratory outcomes in children with spinal muscular atrophy. (2023/04/01) ♡
- Analysis of Feeding Behavior Characteristics in the Cu/Zn Superoxide Dismutase 1 (SOD1) SOD1G93A Mice Model for Amyotrophic Lateral Sclerosis (ALS). (2023/03/28) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Early electroacupuncture intervention delays progression of disease in mice with amyotrophic lateral sclerosis by down-regulating TLR4/NF-κB signaling]. (2023/03/25) ♡
- Videofluoroscopic Dysphagia Scale as an Additional Indicator of Gastrostomy in Patients with Amyotrophic Lateral Sclerosis with Dysphagia. (2023/03/24) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Glial Glutamate Transporter-Mediated Plasticity: System x(c)(-)/xCT/SLC7A11 and EAAT1/2 in Brain Diseases. (2023/03/20) ♡
- In Silico Exploration of Metabolically Active Peptides as Potential Therapeutic Agents against Amyotrophic Lateral Sclerosis. (2023/03/18) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Spinal muscular atrophy and anorexia nervosa: a case report. (2023/03/14) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation. (2023/03/01) ♡
- Genetic landscape of ALS in Malta based on a quinquennial analysis. (2023/03/01) ♡
- Fucoidan from Fucus vesiculosus prevents the loss of dopaminergic neurons by alleviating mitochondrial dysfunction through targeting ATP5F1a. (2023/03/01) ♡
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