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Primary lateral sclerosis
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Publications and studies (2510)
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ketone bodies mediate alterations in brain energy metabolism and biomarkers of Alzheimer's disease. (2023/11/16) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging Role of Plant-Based Bioactive Compounds as Therapeutics in Parkinson's Disease. (2023/11/14) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Spinal muscular atrophy in Ghanaian children confirmed by molecular genetic testing: a case series. (2023/11/09) ♡
- Ideal body weight-based determination of minimum oral calories beneficial to function and survival in ALS. (2023/11/08) ♡
- Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function. (2023/11/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Efficacy, safety and tolerability of high caloric diet in amyotrophic lateral sclerosis patients: A systematic review and meta-analysis. (2023/11/01) ♡
- Longitudinal changes in intrinsic motoneuron excitability in amyotrophic lateral sclerosis are dependent on disease progression. (2023/11/01) ♡
- Big Mistake: Knowing and Doing Better in Patient Engagement. (2023/11/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Investigating brain alterations in the Dp1Tyb mouse model of Down syndrome. (2023/11/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Efficacy of mecasin for treatment of amyotrophic lateral sclerosis: A phase IIa multicenter randomized double-blinded placebo-controlled trial. (2023/10/28) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Effect of electroacupuncture intervention on the spinal cord PPIA/NF-κB signaling pathway in mice with amyotrophic lateral sclerosis. (2023/10/25) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. The Role of Short-Chain Fatty Acids in Microbiota-Gut-Brain Cross-Talk with a Focus on Amyotrophic Lateral Sclerosis: A Systematic Review. (2023/10/11) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Astaxanthin promotes locomotor function recovery and attenuates tissue damage in rats following spinal cord injury: a systematic review and trial sequential analysis. (2023/10/10) ♡
- Effect of tauroursodeoxycholic acid on survival and safety in amyotrophic lateral sclerosis: a retrospective population-based cohort study. (2023/10/05) ♡
- Profiling Number of Swallows per Bolus and Residue in Individuals With Amyotrophic Lateral Sclerosis. (2023/10/04) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Requested withdrawal of gastrostomy feeding in motor neurone disease. (2023/10/01) ♡
- Wuzi Yanzong Pill relieves MPTP-induced motor dysfunction and neuron loss by inhibiting NLRP3 inflammasome-mediated neuroinflammation. (2023/10/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Acupuncture in the Treatment of Amyotrophic Lateral Sclerosis: A Research Progress in Clinical Trials. (2023/10/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. The safety and effectiveness of high-calorie therapy for treating amyotrophic lateral sclerosis: a systematic review and meta-analysis. (2023/10/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Palliative Care in Amyotrophic Lateral Sclerosis. (2023/10/01) ♡
- A critical view of the use of predictive energy equations for the identification of hypermetabolism in motor neuron disease: A pilot study. (2023/10/01) ♡
- Neurological and Psychiatric Aspects of Biological Markers for the Provision of Medical Care to Patients with Spinal Muscular Atrophy 5q. (2023/10/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Spinal Muscular Atrophy. (2023/10/01) ♡
- Fecal microbial transplantation limits neural injury severity and functional deficits in a pediatric piglet traumatic brain injury model. (2023/09/28) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease. (2023/09/26) ♡
- Facilitating Pro-survival Mitophagy for Alleviating Parkinson's Disease via Sequence-Targeted Lycopene Nanodots. (2023/09/26) ♡
- Control in the absence of choice: A qualitative study on decision-making about gastrostomy in people with amyotrophic lateral sclerosis, caregivers, and healthcare professionals. (2023/09/08) ♡
- Interplay of Metallome and Metabolome in Amyotrophic Lateral Sclerosis: A Study on Cerebrospinal Fluid of Patients Carrying Disease-Related Gene Mutations. (2023/09/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nutritional and metabolic factors in amyotrophic lateral sclerosis. (2023/09/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Nutritional rickets masquerading as spinal muscular atrophy type III. (2023/09/01) ♡
- Chronic carbon disulfide exposure induces parkinsonian pathology via α-synuclein aggregation and necrosome complex interaction. (2023/08/30) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Association of Selenium Levels with Neurodegenerative Disease: A Systemic Review and Meta-Analysis. (2023/08/24) ♡
- miRNA profiling as a complementary diagnostic tool for amyotrophic lateral sclerosis. (2023/08/23) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. TANK-Binding Kinase 1 Mutation as a Rare Cause of Frontotemporal Dementia in a Mexican Patient: The First Case Report in a Tertiary Referral Hospital in Mexico. (2023/08/23) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Potential benefits of medium chain fatty acids in aging and neurodegenerative disease. (2023/08/23) ♡
- Association of Polyunsaturated Fatty Acids and Clinical Progression in Patients With ALS: Post Hoc Analysis of the EMPOWER Trial. (2023/08/15) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Enteral tube feeding for amyotrophic lateral sclerosis/motor neuron disease. (2023/08/10) ♡
- MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization. (2023/08/03) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Transcranial magnetic stimulation to monitor disease progression in ALS: a review. (2023/08/01) ♡
- Primary lateral sclerosis natural history study - planning, designing, and early enrollment. (2023/08/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. ALSUntangled # 69: astaxanthin. (2023/08/01) ♡
- Open-labelled study to monitor the effect of an amino acid formula on symptom management in children with spinal muscular atrophy type I: The SMAAF pilot study. (2023/08/01) ♡
- Why is nutrition vital for advancing ALS care and clinical research? (2023/08/01) ♡
- Potential role of vitamin D levels in amyotrophic lateral sclerosis cognitive impairment. (2023/08/01) ♡
- Clinical and demographical characteristics in a cohort of MND patients treated with riluzole. Differences between tablets and oral suspension. (2023/08/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Glucagon-like peptide-1 analog therapy in rare genetic diseases: monogenic obesity, monogenic diabetes, and spinal muscular atrophy. (2023/08/01) ♡
- Mitophagy suppresses motor neuron necroptotic mitochondrial damage and alleviates necroptosis that converges to SARM1 in acrylamide-induced dying-back neuropathy. (2023/08/01) ♡
- NRF2 activation suppresses motor neuron ferroptosis induced by the SOD1(G93A) mutation and exerts neuroprotection in amyotrophic lateral sclerosis. (2023/08/01) ♡
- Onasemnogene abeparvovec preserves bulbar function in infants with presymptomatic spinal muscular atrophy: a post-hoc analysis of the SPR1NT trial. (2023/08/01) ♡
- Amyotrophic Lateral Sclerosis Quality Measurement Set 2022 Update: Quality Improvement in Neurology. (2023/08/01) ♡
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