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Primary lateral sclerosis
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Publications and studies (2510)
- Judicialization of Zolgensma in the Ministry of Health: costs and clinical profile of patients. (2024/08/12) ♡
- Malnutrition in Amyotrophic Lateral Sclerosis: Insights from Morphofunctional Assessment and Global Leadership Initiative on Malnutrition Criteria. (2024/08/09) ♡
- Duple-MONDNet: duple deep learning-based mobile net for motor neuron disease identification. (2024/08/06) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Percutaneous gastrostomy, mechanical ventilation and survival in amyotrophic lateral sclerosis: an observational study in an incident cohort. (2024/08/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. 10 weeks low intensity treadmill exercise intervention ameliorates motor deficits and sustains muscle mass via decreasing oxidative damage and increasing mitochondria function in a rat model of Parkinson's disease. (2024/08/01) ♡
- Factors influencing gastrostomy tube removal. (2024/08/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Advance directives in amyotrophic lateral sclerosis - a systematic review and meta-analysis. (2024/07/29) ♡
- Increased copy-number variant load of associated risk genes in sporadic cases of amyotrophic lateral sclerosis. (2024/07/27) ♡
- Unveiling the adverse events of Nusinersen in spinal muscular atrophy management based on FAERS database. (2024/07/25) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. PRKAG2 Variant, Motor Neuron Disease, and Parkinsonism: Fortuitous Association or a Potentially Underestimated Pathophysiological Mechanism? (2024/07/25) ♡
- Neural Differentiation and spinal cord organoid generation from induced pluripotent stem cells (iPSCs) for ALS modelling and inflammatory screening. (2024/07/01) ♡
- Lnc-HIBADH-4 Regulates Autophagy-Lysosome Pathway in Amyotrophic Lateral Sclerosis by Targeting Cathepsin D. (2024/07/01) ♡
- Combined Treatment with Bojungikgi-tang (Buzhong Yiqi Decoction) and Riluzole Attenuates Cell Death in TDP-43-Expressing Cells. (2024/07/01) ♡
- Lycium barbarum glycopeptide ameliorates motor and visual deficits in autoimmune inflammatory diseases. (2024/07/01) ♡
- The protective effects of repetitive transcranial magnetic stimulation with different high frequencies on motor functions in MPTP/probenecid induced Parkinsonism mouse models. (2024/07/01) ♡
- Outcomes after intervention for enteral nutrition in patients with amyotrophic lateral sclerosis in multidisciplinary clinics. (2024/07/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. An updated systematic review on spinal muscular atrophy patients treated with nusinersen, onasemnogene abeparvovec (at least 24 months), risdiplam (at least 12 months) or combination therapies. (2024/07/01) ♡
- A Multi-branch Attention-based Deep Learning Method for ALS Identification with sMRI Data. (2024/07/01) ♡
- Assessing Pulmonary Function in ALS using Electrical Impedance Tomography. (2024/07/01) ♡
- Does Excessive Tonic Inhibition Cause Unstable Feedback in Parkinson's Disease? (2024/07/01) ♡
- Predicting Amyotrophic Lateral Sclerosis Progression: an EMG-based Survival Analysis. (2024/07/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Medical nutrition therapy in amyotrophic lateral sclerosis - Do we act or react? A case report and multidisciplinary review. (2024/06/27) ♡
- Dietary factors and risk for amyotrophic lateral sclerosis: A two sample mendelian randomization study. (2024/06/21) ♡
- The periprocedural respiratory safety of propofol sedation in patients with a motor neuron disease undergoing percutaneous endoscopic gastrostomy insertion. (2024/06/15) ♡
- Reasons and experience for patients with amyotrophic lateral sclerosis using traditional Chinese medicine: a CARE-TCM based mixed method study. (2024/06/12) ♡
- LIU Zhishun's clinical experience of electroacupuncture for pediatric neurogenic bladder of lower motor neuron type in children. (2024/06/12) ♡
- Purmorphamine, a Smo-Shh/Gli Activator, Promotes Sonic Hedgehog-Mediated Neurogenesis and Restores Behavioural and Neurochemical Deficits in Experimental Model of Multiple Sclerosis. (2024/06/01) ♡
- The lived experience of reconstructing identity in response to genetic risk of frontotemporal degeneration and amyotrophic lateral sclerosis. (2024/06/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Chitinases as a potential diagnostic and prognostic biomarker for amyotrophic lateral sclerosis: a systematic review and meta-analysis. (2024/06/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Edaravone for patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis. (2024/06/01) ♡
- Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. European Academy of Neurology (EAN) guideline on the management of amyotrophic lateral sclerosis in collaboration with European Reference Network for Neuromuscular Diseases (ERN EURO-NMD). (2024/06/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The connection between gut microbiota and its metabolites with neurodegenerative diseases in humans. (2024/06/01) ♡
- Characterization of the skeletal muscle arginine methylome in health and disease reveals remodeling in amyotrophic lateral sclerosis. (2024/05/31) ♡
- Nutritional and lipid profile status of children with spinal muscular atrophy in China: A retrospective case-control study. (2024/05/20) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Efficacy of non-pharmacological interventions for individuals with amyotrophic lateral sclerosis: systematic review and network meta-analysis of randomized control trials. (2024/05/18) ♡
- Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy. (2024/05/09) ♡
- Radiologically Inserted Gastrostomy Tube Placement Guided by the Assessment and Primary Palliative Care Provided by an Amyotrophic Lateral Sclerosis Multidisciplinary Clinic: A Single-Arm Retrospective Clinical Study. (2024/05/01) ♡
- Predicting amyotrophic lateral sclerosis (ALS) progression with machine learning. (2024/05/01) ♡
- Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia. (2024/05/01) ♡
- Premorbid lipid levels and long-term risk of ALS-a population-based cohort study. (2024/05/01) ♡
- ALSUntangled #73: Lion's Mane. (2024/05/01) ♡
- Erythrocytes' surface properties and stiffness predict survival and functional decline in ALS patients. (2024/05/01) ♡
- Time from amyotrophic lateral sclerosis symptom onset to key disease milestones: analysis of data from a multinational cross-sectional survey. (2024/05/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Effect of Intermittent Oro-Esophageal Tube Feeding in Bulbar Palsy After Ischemic Stroke: A Randomized Controlled Study. (2024/05/01) ♡
- Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. The clinical practice guideline for the management of amyotrophic lateral sclerosis in Japan-update 2023. (2024/04/24) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Recent research on home rehabilitation and nursing for spinal muscular atrophy]. (2024/04/15) ♡
- Investigating Repeat Expansions in NIPA1, NOP56, and NOTCH2NLC Genes: A Closer Look at Amyotrophic Lateral Sclerosis Patients from Southern Italy. (2024/04/14) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A pregnant woman with amyotrophic lateral sclerosis from Iran: a case report. (2024/04/03) ♡
- Dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke in middle-aged male and female mice. (2024/04/01) ♡
- Genetics screening in an Italian cohort of patients with Amyotrophic Lateral Sclerosis: the importance of early testing and its implication. (2024/04/01) ♡
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