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Primary lateral sclerosis
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Publications and studies (2510)
- Topological Gait Analysis: A New Framework and Its Application to the Study of Human Gait. (2024/12/01) ♡
- The Causality Spectrum of Dropped Head Syndrome is Broad and Includes Myopathy, Neurodegenerative Disorders, and Varia. (2024/11/30) ♡
- Development of a Sensitive and Reliable Meso Scale Discovery-Based Electrochemiluminescence Immunoassay to Quantify TDP-43 in Human Biofluids. (2024/11/28) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Magnesium (Mg) and Neurodegeneration: A Comprehensive Overview of Studies on Mg Levels in Biological Specimens in Humans Affected Some Neurodegenerative Disorders with an Update on Therapy and Clinical Trials Supplemented with Selected Animal Studies. (2024/11/23) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Concomitant Amyotrophic Lateral Sclerosis and Rheumatoid Arthritis: A Case Report. (2024/11/23) ♡
- VEP Latency Delay Reflects Demyelination Beyond the Optic Nerve in the Cuprizone Model. (2024/11/04) ♡
- L-NRB alleviates amyotrophic lateral sclerosis by regulating P11-Htr4 signaling pathway. (2024/11/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Different intensities of physical activity for amyotrophic lateral sclerosis and Parkinson disease: A Mendelian randomization study and meta-analysis. (2024/11/01) ♡
- Current practices in the nutrition management of people with amyotrophic lateral sclerosis (ALS): a survey of U.S. ALS care teams. (2024/11/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Nutrition outcomes of disease modifying therapies in spinal muscular atrophy: A systematic review. (2024/11/01) ♡
- Prognostic factors for tube feeding in type I SMA patients treated with disease-modifying therapies: a cohort study. (2024/11/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Caring for people living with ALS in Korea: challenges and possible paths forward. (2024/11/01) ♡
- Predictors of mortality post-gastrostomy in motor neuron disease patients. (2024/11/01) ♡
- Total physical activity, plant-based diet and neurodegenerative diseases: A prospective cohort study of the UK biobank. (2024/11/01) ♡
- Outcomes for patients in the RESTORE registry with spinal muscular atrophy and four or more SMN2 gene copies treated with onasemnogene abeparvovec. (2024/11/01) ♡
- Type 1 spinal muscular atrophy treated with nusinersen in Norway, a five-year follow-up. (2024/11/01) ♡
- Type-1 spinal muscular atrophy cohort before and after disease-modifying therapies. (2024/11/01) ♡
- [Diagnosis, Notification, and Managements of ALS: A Personal Perspective from 40 years of Experience as a Clinical Neurologist]. (2024/11/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparative efficacy of risdiplam and nusinersen in Type 2 and 3 spinal muscular atrophy patients: A cohort study using real-world data. (2024/11/01) ♡
- Newborn screening programs for spinal muscular atrophy worldwide in 2023. (2024/11/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Peripheral defects precede neuromuscular pathology in the Smn(2B/-) mouse model of spinal muscular atrophy. (2024/11/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hirayama Disease in a Young Male: A Case Report. (2024/11/01) ♡
- TDP43 aggregation at ER-exit sites impairs ER-to-Golgi transport. (2024/10/19) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Rare coexistence of spinal muscular atrophy with membranous nephropathy - A clinical conundrum with management dilemma. (2024/10/01) ♡
- Electroacupuncture alleviates motor dysfunction by regulating neuromuscular junction disruption and neuronal degeneration in SOD1(G93A) mice. (2024/10/01) ♡
- Intellectual assessment of amyotrophic lateral sclerosis using deep resemble forward neural network. (2024/10/01) ♡
- Circulating endocannabinoidome signatures of disease activity in amyotrophic lateral sclerosis. (2024/10/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Persistent inward currents in human motoneurons: emerging evidence and future directions. (2024/10/01) ♡
- A reassessment of spinal cord pathology in severe infantile spinal muscular atrophy: Reassessment of spinal cord pathology. (2024/10/01) ♡
- Impact of respiratory tract infections on spinal muscular atrophy with focus on respiratory syncytial virus infections: a single-centre cohort study. (2024/10/01) ♡
- Modulation of Autophagy and Nitric Oxide Signaling via Glycyrrhizic Acid and 7-Nitroindazole in MPTP-induced Parkinson's Disease Model. (2024/10/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Intraventricular Administration of Exosomes from Patients with Amyotrophic Lateral Sclerosis Provokes Motor Neuron Disease in Mice. (2024/10/01) ♡
- Autophagy receptor-inspired chimeras: a novel approach to facilitate the removal of protein aggregates and organelle by autophagy degradation. (2024/09/25) ♡
- Scientific evidence of acupuncture for post-stroke motor impairment: protocol for an overview of systematic reviews and meta-analyses. (2024/09/17) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Herbal medicines for SOD1(G93A) mice of amyotrophic lateral sclerosis: preclinical evidence and possible immunologic mechanism. (2024/09/17) ♡
- Bioactivated Glucoraphanin Modulates Genes Involved in Necroptosis on Motor-Neuron-like Nsc-34: A Transcriptomic Study. (2024/09/14) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Fueling Recovery: The Therapeutic Role of Ketogenic Diet in Neurological Pathologies. (2024/09/05) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Neuro-Restorative Effect of Nimodipine and Calcitriol in 1-Methyl 4-Phenyl 1,2,3,6 Tetrahydropyridine-Induced Zebrafish Parkinson's Disease Model. (2024/09/01) ♡
- Primary lateral sclerosis: more than just an upper motor neuron disease. (2024/09/01) ♡
- Nicotinamide Adenine Dinucleotide Precursor Supplementation Modulates Neurite Complexity and Survival in Motor Neurons from Amyotrophic Lateral Sclerosis Models. (2024/09/01) ♡
- Variant-specific effects of GBA1 mutations on dopaminergic neuron proteostasis. (2024/09/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Tongue pressure is a strong predictor of recommendation for gastrostomy in amyotrophic lateral sclerosis. (2024/09/01) ♡
- Spinocerebellar ataxia type 4 is caused by a GGC expansion in the ZFHX3 gene and is associated with prominent dysautonomia and motor neuron signs. (2024/09/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Caffeine consumption outcomes on amyotrophic lateral sclerosis disease progression and cognition. (2024/09/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Exercise training induces mild skeletal muscle adaptations without altering disease progression in a TDP-43 mouse model. (2024/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic lateral sclerosis as a disease model of sarcopenia. (2024/09/01) ♡
- Experiences of families of children with spinal muscular atrophy and the healthcare professionals supporting them during the COVID-19 pandemic: A nationwide study. (2024/09/01) ♡
- CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism. (2024/08/31) ♡
- Real-World Data in Children with Spinal Muscular Atrophy Type 1 on Long-Term Ventilation Receiving Gene Therapy: A Prospective Cohort Study. (2024/08/28) ♡
- Computational Analysis and Experimental Data Exploring the Role of Hesperetin in Ameliorating ADHD and SIRT1/Nrf2/Keap1/OH-1 Signaling. (2024/08/27) ♡
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