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Myelodysplastic syndrome

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (47)Meta-analysis (14)Treatment guideline (3)Systematic review (10)Randomized trial (10)Phase 3 study (10)Clinical trial (605)Review article (239)Early study (phase 1 or 2) (47)Description of individual patients (223)Laboratory or animal studies (12)Commentary or editorial (67) Only studies currently recruiting participants (42)

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Publications and studies (1773)

• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Prognostic significance of U2AF1 mutations in myelodysplastic syndromes: a meta-analysis. (2020/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. 4-Amino-2-trifluoromethyl-phenyl retinate induced differentiation of human myelodysplastic syndromes SKM-1 cell lines by up-regulating DDX23. (2020/03/01) ♡
• Czech and Slovak Diamond-Blackfan Anemia (DBA) Registry update: Clinical data and novel causative genetic lesions. (2020/03/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical features and outcomes of patients with Shwachman-Diamond syndrome and myelodysplastic syndrome or acute myeloid leukaemia: a multicentre, retrospective, cohort study. (2020/03/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Mutational features of myelodysplastic syndromes with Auer rods reveal them are more akin to acute myeloid leukemia. (2020/03/01) ♡
• Iron Overload Mimicking Conditions Skews Bone Marrow Dendritic Cells Differentiation into MHCII(low)CD11c(+)CD11b(+)F4/80(+) Cells. (2020/02/17) ♡
• Broadening the phenotypic spectrum of Pearson syndrome: Five new cases and a review of the literature. (2020/02/01) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial. (2020/02/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Giant-cell arteritis associated with myelodysplastic syndrome: French multicenter case control study and literature review. (2020/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Identification of a novel heterozygous ALAS2 mutation in a young Chinese female with X-linked sideroblastic anemia. (2020/02/01) ♡
• Characteristics of Long-Term Survival in Patients With Myelodysplastic Syndrome Treated With 5-Azacyditine: Results From the Hellenic 5-Azacytidine Registry. (2020/02/01) ♡
• Evaluation of azacitidine in patients with transplant-ineligible myelodysplastic syndromes and acute myeloid leukemia with myelodysplasia-related changes in a Japanese clinical setting. (2020/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies. (2020/01/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Understanding intrinsic hematopoietic stem cell aging. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Assessing clonal haematopoiesis: clinical burdens and benefits of diagnosing myelodysplastic syndrome precursor states. (2020/01/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Prognostic significance of SF3B1 mutations in patients with myelodysplastic syndromes: A meta-analysis. (2020/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A case of polycyclic Sweet's syndrome arising from azacitidine injection sites in myelodysplasia. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Two effects of GATA2 enhancer repositioning by 3q chromosomal rearrangements. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Laboratory Approach to Hemolytic Anemia. (2020/01/01) ♡
• Hypomethylation of MIR-378 5'-flanking region predicts poor survival in young patients with myelodysplastic syndrome. (2020/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. RUNX1 mutation in a patient with myelodysplastic syndrome and decreased erythrocyte expression of blood group A antigen. (2020/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Successful treatment of a PNH patient non-responsive to eculizumab with the novel complement C5 inhibitor coversin (nomacopan). (2020/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The epidemiology of platelet transfusions: an analysis of platelet use at 12 US hospitals. (2020/01/01) ♡
• Myeloid Neoplasms with Elevated Plasmacytoid Dendritic Cell Differentiation Reflect the Maturation Process of Dendritic Cells. (2020/01/01) ♡
• Influence of demethylation on regulatory T and Th17 cells in myelodysplastic syndrome. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Acute myeloid leukemia with complex cytogenetic abnormalities associated with long-term use of oral colloidal silver as nutritional supplement - Case report and review of literature. (2020/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Myelodysplastic syndromes: An analysis of non-hematological prognostic factors and its relationship to age. (2020/01/01) ♡
• Iron Support in Erythropoietin Treatment in Myelodysplastic Syndrome Patients Affected by Low-Risk Refractory Anaemia: Real-Life Evidence from an Italian Setting. (2020/01/01) ♡
• [Evaluation of Micafungin Use in Children]. (2020/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Relationship between Low Pretreatment Geriatric Nutritional Risk Index and Poor Tolerability of Azacitidine in Patients with Myelodysplastic Syndromes. (2020/01/01) ♡
• A Phase 1B Clinical Study of Combretastatin A1 Diphosphate (OXi4503) and Cytarabine (ARA-C) in Combination (OXA) for Patients with Relapsed or Refractory Acute Myeloid Leukemia. (2019/12/26) ♡
• Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia. (2019/12/25) ♡
• Therapy-related acute lymphoblastic leukemia is a distinct entity with adverse genetic features and clinical outcomes. (2019/12/23) ♡
• Bone marrow oxidative stress and specific antioxidant signatures in myelodysplastic syndromes. (2019/12/23) ♡
• Donor and host coexpressing KIR ligands promote NK education after allogeneic hematopoietic stem cell transplantation. (2019/12/23) ♡
• Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression. (2019/12/23) ♡
• CT-guided Core-Needle Biopsy of the Lung Is Safe and More Effective than Fine-Needle Aspiration Biopsy in Patients with Hematologic Malignancies. (2019/12/19) ♡
• [Therapy-related myeloid neoplasms after successful treatment for acute promyelocytic leukemia: a report of four cases and literature review]. (2019/12/14) ♡
• [Clonal evolution of myelodysplastic syndrome]. (2019/12/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Recommended patient information sheet on the impact of haematopoietic cell transplantation on sexual functioning and sexuality. (2019/12/12) ♡
• NKL homeobox gene activities in normal and malignant myeloid cells. (2019/12/11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Aberrant Expression of EZH2 in Pediatric Patients with Myelodysplastic Syndrome: A Potential Biomarker of Leukemic Evolution. (2019/12/10) ♡
• Reanalysing genomic data by normalized coverage values uncovers CNVs in bone marrow failure gene panels. (2019/12/09) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Genetic predisposition to MDS: diagnosis and management. (2019/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Minimal residual disease and stem cell transplantation outcomes. (2019/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Lowering the boom on lower-risk myelodysplastic syndromes. (2019/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Integrating patient-centered factors in the risk assessment of MDS. (2019/12/06) ♡
• Monitoring and treatment of MDS in genetically susceptible persons. (2019/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. In MDS, is higher risk higher reward? (2019/12/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Idiopathic aplastic anemia vs hypocellular myelodysplastic syndrome. (2019/12/06) ♡

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