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Melanoma (metastatic)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the strongest evidence (27)Meta-analysis (4)Treatment guideline (2)Systematic review (8)Phase 3 study (7)Randomized trial (6)Clinical trial (586)Review article (181)Early study (phase 1 or 2) (54)Case reports (243)Laboratory or animal study (45)Commentary or editorial (17)Retracted publication (2) Studies currently recruiting participants only (39)

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Publications and studies (1866)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pilot Study of Biomarkers of Response to Immune Checkpoint Blockade in Metastatic Melanoma (2026-01-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Use of Dendritic Cell/Tumor Hybridomas as a Novel Tumor Vaccine in Patients With Advance Melanoma (2026-01-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Elderly Cancer PatIents, Safety and qualiTy of Life Under immunOtheraPies (2026-01-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivo® in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma (2026-01-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Molecular Characterization of Advanced Stage Melanoma by Blood Sampling (2026-01-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients (2026-01-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma (2026-01-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. IN10018 Monotherapy and Combination Therapy for Metastatic Melanoma (2026-01-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of PLX3397 in Patients With Unresectable or Metastatic KIT-mutated Melanoma (2026-01-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3 (2026-01-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Prospective Observational Study on Targeted Therapy for Unresectable or Metastatic BRAFV600E Mutant Melanoma Patients (2026-01-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma (2026-01-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain (2026-01-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ACTengine® IMA203 Combined With mRNA-4203 (2026-01-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Investigate the Novel Agent BNT111 and Cemiplimab in Combination or as Single Agents in Patients With Advanced Melanoma That Has Not Responded to Other Forms of Treatment (2026-01-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma (2026-01-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Phase 1 Study of [225Ac]-FPI-1434 Injection (2026-01-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma (2026-01-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis (2026-01-02) ♡
• Harnessing the synergy of contact brachytherapy and immune checkpoint inhibitors in advanced melanoma: first reported case series. (2025/12/31) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Spontaneous cSCC Murine Model Shows Limited Response to PD-1 Blockade and Radiation Combination Therapy. (2025/12/31) ♡
• Ephrin Receptors and Ephrin Ligands in Uveal Melanoma: A Big Data Analysis Using Web Resources. (2025/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Intraocular metastasis from an anal squamous cell carcinoma: a case report. (2025/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Duodenal metastases from lung adenocarcinoma causing gastrointestinal bleeding: a rare aetiology. (2025/12/30) ♡
• Metastatic Uveal Melanoma Surveillance: A Delphi Panel Consensus. (2025/12/30) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Subgroup analyses of the phase 3 FOCUS study of melphalan/hepatic delivery system in patients with unresectable metastatic uveal melanoma. (2025/12/29) ♡
• The AKT-p21 phosphorylation signaling axis confers poor prognosis and dacarbazine resistance in melanoma. (2025/12/29) ♡
• Functional inactivation of oligosaccharyltransferase a isoform suppresses tumor metastasis. (2025/12/29) ♡
• Thioredoxin interacting protein (TXNIP), a redox regulator, mediates the RAPGEF3/4 signaling dependency in primary melanoma. (2025/12/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Role of Gut Microbiome in Oncogenesis and Oncotherapies. (2025/12/29) ♡
• Vitreoretinal Surgery for Intraocular Complications Following Radiotherapy Treatment of Uveal Melanoma. (2025/12/27) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Antitumor effects of morphine and tramadol on lung metastasis of melanoma tumor cells in vitro and in vivo. (2025/12/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. "Exosomal blueprint of lung-tropic metastasis: molecular signatures, microenvironmental conditioning, and translational implications in cancer". (2025/12/26) ♡
• Real-world outcomes of talimogene laherparepvec as salvage therapy for advanced melanoma. (2025/12/25) ♡
• Commensal bacteria antigen-mediated immune response enhances anti-tumor immunity. (2025/12/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. MicroRNAs as Diagnostic and Prognostic Biomarkers in Melanoma and Non-Melanoma Skin Cancers: An Updated Review. (2025/12/23) ♡
• Investigating Chronic Toxicity, Diet, Patient-Reported Outcomes and the Microbiome in Immunotherapy-Treated Metastatic Melanoma Survivors: A New Frontier. (2025/12/22) ♡
• Electromagnetic Navigation System with a Marker Option for Computed Tomography-Guided Microwave Ablation of Undetectable or Inconspicuous Hepatic Tumors in Non-Enhanced Scans: A Feasibility Study. (2025/12/21) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review. (2025/12/19) ♡
• Anti-VEGF immunotherapy with HEBERSaVax suppresses melanoma growth and metastasis via angiogenesis blockade and enhanced T-cell infiltration. (2025/12/19) ♡
• Outcome of Ruthenium-106 Brachytherapy for Uveal Melanoma and Retinal Vascular Tumors: A Retrospective Study. (2025/12/19) ♡
• Safety and feasibility of blood-derived multiple antigen-specific endogenously derived T cells (MASE-T) for metastatic melanoma. (2025/12/19) ♡
• Secondary Glaucoma Resulting From Choroidal Melanoma in a Patient With Congenital Nevus of Ota. (2025/12/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Bilateral Cerebellopontine Angle Masses in a 72-Year-Old Woman With Prior Malignant Melanoma and a Cochlear Implant: A Diagnostic and Management Challenge. (2025/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Canonical and noncanonical NF-κB signaling in uveal melanoma: mechanisms, microenvironment, and therapeutic modulation. (2025/12/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case Report: Multiple immune related adverse events in a patient with metastatic melanoma. (2025/12/16) ♡
• Extracorporeal photopheresis as a therapeutic approach for treatment resistant immune-related adverse events in anti-PD-1-treated melanoma patients. (2025/12/16) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Tumoral Melanosis: A Benign Mimicker of Malignant Disease. (2025/12/16) ♡
• Mechanisms of tumor persistence in metastatic melanoma following successful immunotherapy. (2025/12/15) ♡
• Radiation exposure to deep brain stimulation leads during multiple cranial radiation courses: illustrative case. (2025/12/15) ♡

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