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Lewy body dementia
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Publications and studies (1347)
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Biomarkers for Lewy body diseases and other alpha-synucleinopathies in biofluids: current evidence and future directions. (2025/11/26) ♡
- Evidence for divergent cortical organisation in Parkinson's disease and Lewy Body Dementia. (2025/11/25) ♡
- Activated microglial exosomes enhance α-Synuclein internalization and accelerate neurodegeneration in lewy body dementia. (2025/11/25) ♡
- Comparative Study on Multimodal Imaging Applications in Dementia with Lewy Bodies: From Imaging Features to Clinical Practice Implications. (2025/11/25) ♡
- Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Safety and efficacy of pimavanserin in patients with Lewy body dementia experiencing dementia-related psychosis in the HARMONY study. (2025/11/24) ♡
- Immune Profiling in Early Cognitive Disorders (IMPRINT) study protocol: a longitudinal cohort study exploring biomarkers of inflammation in early dementia with Lewy bodies and Alzheimer's disease, as part of the Dementias Platform UK. (2025/11/21) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Role of Skin Innervation for Assessment of Neurological Involvement in Disorders: A Review. (2025/11/21) ♡
- Single cell long read whole genome sequencing reveals somatic transposon activity in human brain. (2025/11/20) ♡
- Does Platelet Transcriptome Dysregulation Across the Lewy Body Continuum Mirror Neuronal Dysfunction? (2025/11/19) ♡
- Long term cognitive outcome of prodromal and mild dementia with Lewy bodies: a cohort study. (2025/11/18) ♡
- High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer's disease phenotypes in a large mixed-dementia cohort. (2025/11/17) ♡
- Lack of epistatic interaction of SNCA with APOE in synucleinopathies. (2025/11/17) ♡
- CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology. (2025/11/14) ♡
- Neuropathological Correlates of Apathy Progression in Alzheimer's Disease and Related Dementias: A Longitudinal NACC Cohort Study. (2025/11/10) ♡
- The Christchurch point mutation in mouse APOE reduces Aβ-induced tau and α-synuclein pathologies. (2025/11/07) ♡
- C-reactive protein predicts functional decline in older adults newly diagnosed with dementia: A 5-year follow-up study. (2025/11/01) ♡
- Putaminal hypermetabolism identifies Lewy body co-pathology in Alzheimer's disease. (2025/11/01) ♡
- Remote, self-administered, smartphone cognitive testing in a registry-based cohort: Feasibility, reliability, and validity findings. (2025/10/30) ♡
- Design, Synthesis and Evaluation of the First 2-Alkynyl(aza)indole (18)F Probe Targeting α-Synuclein Aggregates. (2025/10/29) ♡
- Nanocarrier-Based Therapies: A Breakthrough in Parkinson's Disease Management. (2025/10/28) ♡
- Cholinergic white matter pathways integrity in prodromal and early manifest Lewy body disease. (2025/10/24) ♡
- APOE3 astrocytes can rescue lipid abnormalities and dystrophic neurites of APOE4 human neurons. (2025/10/24) ♡
- Affective Neuropsychiatric Symptom Metrics in the National Alzheimer's Coordinating Center Dataset. (2025/10/24) ♡
- A Split Biotin Ligase Approach to Revealing Proteins Associated with Oligomeric Alpha-Synuclein During Aggregation. (2025/10/17) ♡
- Exosome-rich mesenchymal stem cell secretome improves strength in patients with amyotrophic lateral sclerosis, Kennedy disease, congenital myasthenic syndrome and Lewy body dementia. (2025/10/15) ♡
- Making Sense of Visual Hallucinations in Lewy Body Dementia for Informal Caregivers: An Interpretative Phenomenological Analysis. (2025/10/01) ♡
- Iron species in cerebrospinal fluid and dementia risk in subjects with mild cognitive impairment: A cohort study. (2025/09/01) ♡
- [Frailty in dementia with Lewy bodies: relationship with clinical features, intrinsic capacity and cognitive and functional decline]. (2025/09/01) ♡
- Sex and gender differences in Lewy body dementia: a narrative review. (2025/09/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Delirium derived from dementia with Lewy bodies in the cancer perioperative period: a case report. (2025/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha-synuclein fibril structures cluster into distinct classes. (2025/08/19) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. SynNeurGe: The road ahead for a biological definition of Parkinson's disease. (2025/08/01) ♡
- Separating dementia with Lewy bodies from Alzheimer's disease dementia using a volumetric MRI classifier. (2025/07/01) ♡
- Exploring the impact of coffee consumption and caffeine intake on cognitive performance in older adults: a comprehensive analysis using NHANES data and gene correlation analysis. (2025/07/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Amyloid-beta pathology in a case with dementia with Lewy bodies with a rapidly progressive clinical course similar to Creutzfeldt-Jacob disease. (2025/06/01) ♡
- Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD): Executive summary of recommendations for primary care. (2025/06/01) ♡
- Intrinsic capacity in patients with dementia with Lewy bodies compared with those with Alzheimer's disease: A cross-sectional study. (2025/06/01) ♡
- Protein co-aggregates of dense core amyloid plaques and CSF differ in rapidly progressive Alzheimer's disease and slower sporadic Alzheimer's disease. (2025/05/27) ♡
- Correlation analyses between MIBG myocardial scintigraphy and monoamine levels in dementia with Lewy bodies show potential link with the serotonergic system. (2025/05/12) ♡
- The protective role of basal metabolic rate in cognitive decline: evidence from epidemiological and genetic studies. (2025/04/22) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. The pharmacodynamics-based prophylactic benefits of GLP-1 receptor agonists and SGLT2 inhibitors on neurodegenerative diseases: evidence from a network meta-analysis. (2025/04/07) ♡
- Episodic Coma in Lewy Body Disorders: An Observational Report. (2025/04/01) ♡
- Decreased urinary excretion of norepinephrine and dopamine in autonomic synucleinopathies. (2025/04/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Impact of Nutrition on the Gut Microbiota: Implications for Parkinson's Disease. (2025/04/01) ♡
- Genetic insights of lipid metabolism and lipid-lowering drugs with Lewy body dementia risk: Evidence from Mendelian randomization. (2025/03/20) ♡
- Human induced pluripotent stem cell-derived dopaminergic neurons release alpha-synuclein through neuronal activity. (2025/03/01) ♡
- Comparison of cerebral technetium-99m-ethyl cysteinate dimer perfusion in patients with dementia with Lewy bodies and Parkinson's disease dementia. (2025/03/01) ♡
- Epigenetic and Metabolic Landscape of Dementia with Lewy Bodies. (2025/03/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Do we need to assess autonomic dysfunction in Lewy body dementia? (2025/03/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Vinpocetine and Lactobacillus Attenuated Rotenone-Induced Parkinson's Disease and Restored Dopamine Synthesis in Rats through Modulation of Oxidative Stress, Neuroinflammation, and Lewy Bodies Inclusion. (2025/02/15) ♡
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