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Lewy body dementia
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Publications and studies (1347)
- Myocardial MIBG scintigraphy in genetic Parkinson's disease as a model for Lewy body disorders. (2019/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model. (2019/02/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Red flags phenotyping: A systematic review on clinical features in atypical parkinsonian disorders. (2019/02/01) ♡
- Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the SNCA gene. (2019/02/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. The risk of neurodegeneration in REM sleep behavior disorder: A systematic review and meta-analysis of longitudinal studies. (2019/02/01) ♡
- Alpha-synuclein is highly prone to distribution in the hippocampus and midbrain in tree shrews, and its fibrils seed Lewy body-like pathology in primary neurons. (2019/02/01) ♡
- A comparison of visual hallucinations across disorders. (2019/02/01) ♡
- Association of brain heptachlor epoxide and other organochlorine compounds with lewy pathology. (2019/02/01) ♡
- Mass synaptometry: High-dimensional multi parametric assay for single synapses. (2019/01/15) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Essential Tremor and Parkinson's Disease: Exploring the Relationship. (2019/01/09) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The heart of PD: Lewy body diseases as neurocardiologic disorders. (2019/01/01) ♡
- Count-based method for specific binding ratio calculation in [I-123]FP-CIT SPECT analysis. (2019/01/01) ♡
- Cause of Death and End-of-Life Experiences in Individuals with Dementia with Lewy Bodies. (2019/01/01) ♡
- Beta amyloid deposition maps onto hippocampal and subiculum atrophy in dementia with Lewy bodies. (2019/01/01) ♡
- Submandibular gland is a suitable site for alpha synuclein pathology in Parkinson disease. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Expression of α-synuclein is regulated in a neuronal cell type-dependent manner. (2019/01/01) ♡
- Parkinsonian GM2 synthase knockout mice lacking mature gangliosides develop urinary dysfunction and neurogenic bladder. (2019/01/01) ♡
- Neuroimaging in dementia. Clinical-radiological correlation. (2019/01/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. LRP10: A novel disease gene bridging Parkinson's disease and dementia with Lewy body. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular Imaging of Dementia With Lewy Bodies. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Structural and Functional Magnetic Resonance Imaging of Dementia With Lewy Bodies. (2019/01/01) ♡
- Clinical and Imaging Characteristics Associated with Color Vision Impairment in Lewy Body Disease. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Behavioral symptomatology and psychopharmacology of Lewy body dementia. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Cingulate cortex in Parkinson's disease. (2019/01/01) ♡
- APOE ɛ4/ɛ4 Is Associated with Aberrant Motor Behavior Through Both Lewy Body and Cerebral Amyloid Angiopathy Pathology in High Alzheimer's Disease Pathological Load. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Recognizing and treating atypical Parkinson disorders. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neurologic examination in the elderly. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. How to approach a patient with parkinsonism - red flags for atypical parkinsonism. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Animal models of synucleinopathies: prion-like propagation of alpha-synuclein in wild-type animals]. (2019/01/01) ♡
- [Clinical and neuroimaging heterogeneity of dementia with Lewy bodies]. (2019/01/01) ♡
- Increased weighting on prior knowledge in Lewy body-associated visual hallucinations. (2019/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Associations Between APOE Variants, Tau and α-Synuclein. (2019/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Determine the Metabolism and Elimination of [14C]E2027 in Healthy Male Participants (2019-12-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biomarkers in Neurodegenerative Diseases (2019-11-12) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. FDG Metabolism in Dementia With Lewy Body (DLB) Patients as Indicated by PET Dynamic Acquisition (2019-11-06) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. DC Longitudinal Study on Aging and Specimen Bank (2019-10-24) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Assess Safety, Tolerability, and Efficacy of HTL0018318 in Patients With Dementia With Lewy Bodies (2019-10-01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biomarkers in Neural Disorders (2019-07-18) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study Evaluating Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: The HEADWAY-DLB Study (2019-04-26) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder (2019-03-27) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers (2019-02-05) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB) (2019-01-08) ♡
- FLIM analysis of intracellular markers associated with the development of Parkinson's disease in cellular model. (2018/12/31) ♡
- Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies. (2018/12/27) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Parkinson's Disease: Etiology, Neuropathology, and Pathogenesis. (2018/12/21) ♡
- Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB. (2018/12/18) ♡
- Antemortem CSF Aβ42/Aβ40 ratio predicts Alzheimer's disease pathology better than Aβ42 in rapidly progressive dementias. (2018/12/14) ♡
- Levodopa-induced dyskinesia in Parkinson disease: A population-based cohort study. (2018/12/11) ♡
- Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions. (2018/12/07) ♡
- High Occurrence of Psychiatric Disorders and Suicidal Behavior Across Dementia Subtypes. (2018/12/01) ♡
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