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Lewy body dementia
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Publications and studies (1347)
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders (2023-03-22) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of anle138b in Parkinson's Disease (2023-03-22) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ANeED Joint Effort 21: eHealth and a PPI Program in Dementia With Lewy Bodies (DLB) (2023-03-17) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Implementation and Evaluation of Improved Access to Medical Imaging for Geriatric Patients of The Royal Ottawa Hospital (2023-03-06) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Home-based Family Caregiver-delivered Music and Reading Interventions for People With Dementia (2023-02-09) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia (2023-01-25) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha-synuclein: a pathological factor with Aβ and tau and biomarker in Alzheimer's disease. (2022/12/31) ♡
- Optimizing cCOG, a Web-based tool, to detect dementia with Lewy Bodies. (2022/12/22) ♡
- Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies. (2022/12/20) ♡
- Differences in Striatal Metabolism in [(18)F]FDG PET in Parkinson's Disease and Atypical Parkinsonism. (2022/12/20) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. The impact of integrated brain molecular PET measures on DLB cognitive phenotype and clinical course. (2022/12/19) ♡
- Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance. (2022/12/19) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gut-brain axis: Review on the association between Parkinson's disease and plant lectins. (2022/12/19) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Treatment needs of dementia with Lewy bodies according to patients, caregivers, and physicians: a cross-sectional, observational, questionnaire-based study in Japan. (2022/12/15) ♡
- Intracellular Accumulation of α-Synuclein Aggregates Promotes S-Nitrosylation of MAP1A Leading to Decreased NMDAR-Evoked Calcium Influx and Loss of Mature Synaptic Spines. (2022/12/14) ♡
- Pyrogallol, Corilagin and Chebulagic acid target the "fuzzy coat" of alpha-synuclein to inhibit the fibrillization of the protein. (2022/12/14) ♡
- Changes in both top-down and bottom-up effective connectivity drive visual hallucinations in Parkinson's disease. (2022/12/14) ♡
- SOBA: Development and testing of a soluble oligomer binding assay for detection of amyloidogenic toxic oligomers. (2022/12/13) ♡
- Distribution of Lewy-related pathology in the brain, spinal cord, and periphery: the population-based Vantaa 85+ study. (2022/12/12) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. The importance of co-pathologies on neuropsychiatric symptoms in dementia. (2022/12/09) ♡
- Inhibition of α-Synuclein Seeding-Dependent Aggregation by ssDNA Aptamers Specific to C-Terminally Truncated α-Synuclein Fibrils. (2022/12/07) ♡
- Axonal degeneration in the anterior insular cortex is associated with Alzheimer's co-pathology in Parkinson's disease and dementia with Lewy bodies. (2022/12/07) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Investigating neurological symptoms of infectious diseases like COVID-19 leading to a deeper understanding of neurodegenerative disorders such as Parkinson's disease. (2022/12/07) ♡
- Association between antidementia medication use and mortality in people diagnosed with dementia with Lewy bodies in the UK: A retrospective cohort study. (2022/12/06) ♡
- Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects. (2022/12/05) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Aggregated Alpha-Synuclein Inclusions within the Nucleus Predict Impending Neuronal Cell Death in a Mouse Model of Parkinsonism. (2022/12/04) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Lysophospholipids: A Potential Drug Candidates for Neurodegenerative Disorders. (2022/12/03) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Therapeutics of Alzheimer's Disease: Recent Developments. (2022/12/03) ♡
- The amplification of CNS damage in Alzheimer's disease due to SARS-CoV2 infection. (2022/12/01) ♡
- Diverse limbic comorbidities cause limbic and temporal atrophy in Lewy body disease. (2022/12/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Role of β2-Adrenergic Receptor Agonist in the Cognitive Impairment Associated with Neurodegenerative Diseases]. (2022/12/01) ♡
- Psychometric properties of the Autonomic Symptoms Checklist in the Lewy body disease module of the uniform dataset. (2022/12/01) ♡
- Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Safety and efficacy of continuous subcutaneous foslevodopa-foscarbidopa in patients with advanced Parkinson's disease: a randomised, double-blind, active-controlled, phase 3 trial. (2022/12/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A reference human induced pluripotent stem cell line for large-scale collaborative studies. (2022/12/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Cinema and Neurocognitive Disorders]. (2022/12/01) ♡
- A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson's disease. (2022/11/30) ♡
- Repetitive mild TBI causes pTau aggregation in nigra without altering preexisting fibril induced Parkinson's-like pathology burden. (2022/11/26) ♡
- Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential. (2022/11/22) ♡
- The role of tyrosine hydroxylase-dopamine pathway in Parkinson's disease pathogenesis. (2022/11/21) ♡
- Calmodulin Binding Domains in Critical Risk Proteins Involved in Neurodegeneration. (2022/11/21) ♡
- Human pericytes degrade diverse α-synuclein aggregates. (2022/11/18) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. How important is the N-terminal acetylation of alpha-synuclein for its function and aggregation into amyloids? (2022/11/16) ♡
- Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation. (2022/11/16) ♡
- Prominent astrocytic alpha-synuclein pathology with unique post-translational modification signatures unveiled across Lewy body disorders. (2022/11/12) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia-an international Delphi consensus. (2022/11/11) ♡
- The Proteome of Neuromelanin Granules in Dementia with Lewy Bodies. (2022/11/09) ♡
- Implication of EEG theta/alpha and theta/beta ratio in Alzheimer's and Lewy body disease. (2022/11/04) ♡
- Cerebrospinal Fluid Alpha-Synuclein Improves the Differentiation between Dementia with Lewy Bodies and Alzheimer's Disease in Clinical Practice. (2022/11/04) ♡
- Neurodegenerative Disorder Risk in Krabbe Disease Carriers. (2022/11/04) ♡
- Optic radiation atrophy in Lewy body disease with visual hallucination on phase difference enhanced magnetic resonance images. (2022/11/03) ♡
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