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Huntington's disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (74)Meta-analysis (18)Treatment guideline (1)Systematic review (22)Randomized trial (21)Phase 3 study (12)Clinical trial (304)Review article (501)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (84)Case report (42)Commentary or editorial (37)Retracted Publication (4) Only studies currently recruiting participants (27)

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Publications and studies (1912)

• Loss of Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Links Nonalcoholic Steatohepatitis to Atherosclerosis. (2020/09/03) ♡
• A role of cellular translation regulation associated with toxic Huntingtin protein. (2020/09/01) ♡
• Identifying disease-associated biomarker network features through conditional graphical model. (2020/09/01) ♡
• The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain. (2020/09/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial. (2020/09/01) ♡
• The SMYD1 and skNAC transcription factors contribute to neurodegenerative diseases. (2020/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Environment and Gene Association With Obesity and Their Impact on Neurodegenerative and Neurodevelopmental Diseases. (2020/08/28) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Vitamin D and Hyperkinetic Movement Disorders: A Systematic Review. (2020/08/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Strain-level epidemiology of microbial communities and the human microbiome. (2020/08/13) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Coenzyme Q10 supplementation in acute ischemic stroke: Is it beneficial in short-term administration? (2020/08/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review. (2020/08/01) ♡
• Ethical Considerations for Food and Beverage Warnings. (2020/08/01) ♡
• Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. Central Role for Adipocyte Na,K-ATPase Oxidant Amplification Loop in the Pathogenesis of Experimental Uremic Cardiomyopathy. (2020/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Myricetin bioactive effects: moving from preclinical evidence to potential clinical applications. (2020/08/01) ♡
• Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice. (2020/07/22) ♡
• The Mediterranean diet, plasma metabolome, and cardiovascular disease risk. (2020/07/21) ♡
• Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival. (2020/07/20) ♡
• Structure-property studies of an imidazoquinoline chemotype with antitrypanosomal activity. (2020/07/10) ♡
• Intake of whole grain foods and risk of type 2 diabetes: results from three prospective cohort studies. (2020/07/08) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates. (2020/07/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates. (2020/07/01) ♡
• Discovery of sultam-containing small-molecule disruptors of the huntingtin-calmodulin protein-protein interaction. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neurodegenerative diseases and Withania somnifera (L.): An update. (2020/06/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ongoing Research on the Role of Gintonin in the Management of Neurodegenerative Disorders. (2020/06/15) ♡
• Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. RETRACTED: Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice. (2020/06/04) ♡
• Psychometric properties and responsiveness of Neuro-QoL Cognitive Function in persons with Huntington disease (HD). (2020/05/01) ♡
• Hypomethylating agent (HMA) therapy use and survival in older adults with Refractory Anemia with Excess Blasts (RAEB) in the United States (USA): a large propensity score-matched population-based study(†). (2020/05/01) ♡
• Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington's Disease. (2020/05/01) ♡
• Identifying metabolomic profiles of inflammatory diets in postmenopausal women. (2020/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review. (2020/05/01) ♡
• The relationship between lifestyle and serum neurofilament light protein in Huntington's disease. (2020/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Potential for Natural Antioxidant Supplementation in the Early Stages of Neurodegenerative Disorders. (2020/04/09) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease. (2020/04/03) ♡
• Late-onset Huntington's disease with 40-42 CAG expansion. (2020/04/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Neuroprotective Effects of Doxycycline in the R6/2 Mouse Model of Huntington's Disease. (2020/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Strategies for mutant gene expression silencing in Huntington's disease therapy]. (2020/03/25) ♡
• Meal Patterns and Changes in Cardiometabolic Risk Factors in Children: A Longitudinal Analysis. (2020/03/18) ♡
• Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants. (2020/03/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanisms of Regulation of Transporters of Amino Acid Absorption in Inflammatory Bowel Diseases. (2020/03/12) ♡
• Universal RNAi Triggers for the Specific Inhibition of Mutant Huntingtin, Atrophin-1, Ataxin-3, and Ataxin-7 Expression. (2020/03/06) ♡
• Metformin reduces prion infection in neuronal cells by enhancing autophagy. (2020/03/05) ♡
• Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. (2020/03/04) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Egg consumption and risk of cardiovascular disease: three large prospective US cohort studies, systematic review, and updated meta-analysis. (2020/03/04) ♡
• Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntington's Disease Cells. (2020/03/01) ♡
• Twist1 Plays an Anti-apoptotic Role in Mutant Huntingtin Expression Striatal Progenitor Cells. (2020/03/01) ♡
• Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons. (2020/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Detergent-free extraction of a functional low-expressing GPCR from a human cell line. (2020/03/01) ♡
• Neuroendocrine Disturbances in Neurodegenerative Disorders: A Scoping Review. (2020/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metal homeostasis disturbances in neurodegenerative disorders, with special emphasis on Creutzfeldt-Jakob disease - Potential pathogenetic mechanism and therapeutic implications. (2020/03/01) ♡
• Allergy, asthma, and the risk of breast and prostate cancer: a Mendelian randomization study. (2020/03/01) ♡

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