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Huntington's disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (74)Meta-analysis (18)Treatment guideline (1)Systematic review (22)Randomized trial (21)Phase 3 study (12)Clinical trial (304)Overview article (505)Early-stage study (phase 1 or 2) (13)Laboratory or animal study (86)Case report (42)Commentary or editorial (37)Retracted Publication (4) Only studies currently recruiting participants (27)

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Publications and studies (1919)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. SIRT1 and SIRT2 Activity Control in Neurodegenerative Diseases. (2021/01/12) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Quantification of Huntington's Disease Related Markers in the R6/2 Mouse Model. (2021/01/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Defective Autophagy and Mitophagy in Aging and Alzheimer's Disease. (2021/01/08) ♡
• Community-level risk & protective correlates of violent crimes. (2021/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The role of transferrins and iron-related proteins in brain iron transport: applications to neurological diseases. (2021/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Uniting homeostatic plasticity and exosome biology: A revision of the conceptual framework for drug discovery in neurodegenerative diseases? (2021/01/01) ♡
• Predicting an optimal composite outcome variable for Huntington's disease clinical trials. (2021/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Expanding the Arsenal Against Huntington's Disease-Herbal Drugs and Their Nanoformulations. (2021/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Therapeutic and Mechanistic Effects of Curcumin in Huntington's Disease. (2021/01/01) ♡
• Dietary education programs for adults with neurological diseases: a scoping review protocol. (2021/01/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Melatonin and curcumin reestablish disturbed circadian gene expressions and restore locomotion ability and eclosion behavior in Drosophila model of Huntington's disease. (2021/01/01) ♡
• A sad heart: Depression and favorable cardiovascular health in Brazil. (2021/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neurodegenerative Diseases and Flavonoids: Special Reference to Kaempferol. (2021/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Metabolic pathways controlled by E3 ligases: an opportunity for therapeutic targeting]. (2021/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Housing R6/2 Mice with Wild-Type Littermates Increases Lifespan. (2021/01/01) ♡
• Quantifying the Onset of Unintended Weight Loss in Huntington's Disease: A Retrospective Analysis of Enroll-HD. (2021/01/01) ♡
• Nonalcoholic fatty liver disease-related hepatocellular carcinoma growth rates and their clinical outcomes. (2021/01/01) ♡
• Moderate Intensity Exercise in Pre-manifest Huntington's Disease: Results of a 6 months Trial. (2021/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate Sigma-1 and Dopamine-2 Receptor Occupancy by Pridopidine in the Human Brain of Healthy Volunteers and in Patients With Huntington's Disease (2021-11-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Alternatives for Reducing Chorea in Huntington Disease (2021-11-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. European Registry on Rare Neurological Diseases (2021-09-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study Evaluating if Pridopidine is Safe, Efficacious, and Tolerable in Patients With Huntington's Disease (2021-09-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Non-invasive Brain Stimulation in Huntington's Disease (2021-09-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Tolerability Study With VY-HTT01, in Adults With Early Manifesting Huntington's Disease (2021-08-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease (2021-08-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Phase 2, to Evaluating the Safety and Efficacy of Pridopidine Vs Placebo for Symptomatic Treatment in Patients With Huntington's Disease (2021-07-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson Disease (2021-07-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Symptomatic Therapy for Patients With Huntington's Disease (2021-04-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. NIPD on cffDNA for Triplet Repeat Diseases (2021-01-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of Memantine to Treat Huntington's Disease (2021-01-05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease. (2020/12/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Perspective insights of repurposing the pleiotropic efficacy of statins in neurodegenerative disorders: An expository appraisal. (2020/12/31) ♡
• Bioinformatic analysis of a microRNA regulatory network in Huntington's disease. (2020/12/30) ♡
• Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington's disease. (2020/12/28) ♡
• Central Cognitive Processing Speed Is an Early Marker of Huntington's Disease Onset. (2020/12/28) ♡
• Exercise Improves Endothelial Function Associated with Alleviated Inflammation and Oxidative Stress of Perivascular Adipose Tissue in Type 2 Diabetic Mice. (2020/12/26) ♡
• Who and Why? Requests for Presymptomatic Genetic Testing for Amyotrophic Lateral Sclerosis/Frontotemporal Dementia vs Huntington Disease. (2020/12/24) ♡
• Glioblastoma CUSA Fluid Protein Profiling: A Comparative Investigation of the Core and Peripheral Tumor Zones. (2020/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Target Molecules of STIM Proteins in the Central Nervous System. (2020/12/23) ♡
• Chemically Induced Models of Parkinson's Disease: History and Perspectives for the Involvement of Ferroptosis. (2020/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington's Disease. (2020/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Determining the Fate of Neurons in SCA3: ATX3, a Rising Decision Maker in Response to DNA Stresses and Beyond. (2020/12/23) ♡
• Peripheral Levels of Renin-Angiotensin System Components Are Associated With Cognitive Performance in Huntington's Disease. (2020/12/18) ♡
• AggreCount: an unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially defined manner. (2020/12/18) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Analysis of mutant and total huntingtin expression in Huntington's disease murine models. (2020/12/17) ♡
• EEG Functional Connectivity and Cognitive Variables in Premanifest and Manifest Huntington's Disease: EEG Low-Resolution Brain Electromagnetic Tomography (LORETA) Study. (2020/12/17) ♡
• Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington's disease. (2020/12/16) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Dissociative Tremor Response with Pallidal Deep Brain Stimulation in Parkinson's Disease. (2020/12/16) ♡
• Accumulation of Cerebrospinal Fluid Glycerophospholipids and Sphingolipids in Cognitively Healthy Participants With Alzheimer's Biomarkers Precedes Lipolysis in the Dementia Stage. (2020/12/16) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Solid Lipid Curcumin Particles Protect Medium Spiny Neuronal Morphology, and Reduce Learning and Memory Deficits in the YAC128 Mouse Model of Huntington's Disease. (2020/12/15) ♡

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