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Huntington's disease
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Publications and studies (1912)
- An analysis of neurovascular disease markers in the hippocampus of Tupaia chinensis at different growth stages. (2023/01/17) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Brain-protective mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells via circRNAs as a potential therapeutic approach for neurodegenerative diseases. (2023/01/16) ♡
- Design and Evaluation of [(18)F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates. (2023/01/12) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case report: Cerebellar sparing in juvenile Huntington's disease. (2023/01/11) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Curcumin-Based Nanomedicines in the Treatment of Inflammatory and Immunomodulated Diseases: An Evidence-Based Comprehensive Review. (2023/01/10) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report. (2023/01/09) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Small molecules to perform big roles: The search for Parkinson's and Huntington's disease therapeutics. (2023/01/09) ♡
- Assessment of movement disorders using wearable sensors during upper limb tasks: A scoping review. (2023/01/09) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. An insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of Moringa oleifera. (2023/01/05) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Repaglinide Elicits a Neuroprotective Effect in Rotenone-Induced Parkinson's Disease in Rats: Emphasis on Targeting the DREAM-ER Stress BiP/ATF6/CHOP Trajectory and Activation of Mitophagy. (2023/01/04) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The role of altered protein acetylation in neurodegenerative disease. (2023/01/04) ♡
- Reduced D(2) /D(3) Receptor Binding and Glucose Metabolism in a Macaque Model of Huntington's Disease. (2023/01/01) ♡
- Reduced-penetrance Huntington's disease-causing alleles with 39 CAG trinucleotide repeats could be a genetic factor of amyotrophic lateral sclerosis. (2023/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Targeting the Nrf2 signaling pathway using phytochemical ingredients: A novel therapeutic road map to combat neurodegenerative diseases. (2023/01/01) ♡
- Endocytosis of AMPA receptors: Role in neurological conditions. (2023/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Carbon-Based Electrochemical Sensors for In Vivo and In Vitro Neurotransmitter Detection. (2023/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging Promise of Phytochemicals in Ameliorating Neurological Disorders. (2023/01/01) ♡
- Prevention of Alzheimer's Disease and Cognitive Decline with Diet and Lifestyle: Proceedings of the A. G. Leventis Foundation Conference. (2023/01/01) ♡
- Methods to Study Mitochondria: Techniques Used to Study the Effects of Age-Related Diseases Including Alzheimer's. (2023/01/01) ♡
- Post-Disaster Mental Health and Dietary Patterns among Older Survivors of an Earthquake and Tsunami. (2023/01/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. The Moderating Role of Race and Ethnicity in the Association Between Cognitive Performance and Functional Abilities in Later Life. (2023/01/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Chorea in the Elderly: A Differential Diagnosis and Case Report of Late-Onset Huntington's Disease in an Octogenarian. (2023/01/01) ♡
- An Overview of Specialist Services for Huntington's Disease in the United Kingdom. (2023/01/01) ♡
- Dysregulation of Human Juvenile Huntington's Disease Brain Proteomes in Cortex and Putamen Involves Mitochondrial and Neuropeptide Systems. (2023/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Measuring Cortisol Levels in Persons With Parkinson's (PD) (2023-12-22) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Biospecimen and Clinical Data Study on Patients for Drug & Biomarker Discovery (2023-11-22) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Assessing Efficacy of Neuropsychiatric Assessment and Treatment Protocols in Huntington's Disease Patients (2023-11-15) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Examination of Quantitative Electroencephalographic (QEEG) Biomarkers in Huntington's Disease (2023-11-09) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Safety of NestaCell® in Huntington's Disease (2023-10-24) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Making HD Voices Heard (2023-10-12) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington Disease (2023-10-11) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Individuals Patterns of Disclosure About Huntington s Disease (HD) and the Association With Adaptation to HD (2023-10-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Efficacy of Fenofibrate as a Treatment for Huntington's Disease (2023-09-28) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Development of the Virtual Unified Huntington's Disease Rating Scale (2023-09-28) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Pridopidine (ACR16) for the Treatment of Participants With Huntington's Disease (2023-08-31) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored Studies (2023-08-31) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Treatment With Pridopidine (ACR16) in Participants With Huntington's Disease (2023-08-29) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease (2023-07-20) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Striatum and Hippocampus on Different Time Scales (2023-07-12) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Impact of Apathy on Caregiving in HD. Version 1 (2023-06-22) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Benchmarking Integrated Care for People Living With Huntington's Disease in England (2023-05-19) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Melatonin for Huntington's Disease (HD) Gene Carriers With HD Related Sleep Disturbance - a Pilot Study (2023-05-15) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. iMagemHTT: FIH Evaluation of Novel Mutant Huntingtin PET Radioligands [¹¹C]CHDI-00485180-R and [¹¹C]CHDI-00485626 (2023-05-06) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. An Open Label Study of ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease (2023-01-31) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Fullerenols Prevent Neuron Death and Reduce Oxidative Stress in Drosophila Huntington's Disease Model. (2022/12/31) ♡
- The length of uninterrupted CAG repeats in stem regions of repeat disease associated hairpins determines the amount of short CAG oligonucleotides that are toxic to cells through RNA interference. (2022/12/30) ♡
- Excessive response to provocation rather than disinhibition mediates irritable behaviour in Huntington's disease. (2022/12/29) ♡
- Reduction in PA28αβ activation in HD mouse brain correlates to increased mHTT aggregation in cell models. (2022/12/27) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. (2022/12/27) ♡
- Toward structural-omics of the bovine retinal pigment epithelium. (2022/12/27) ♡
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