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Huntington's disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (74)Meta-analysis (18)Treatment guideline (1)Systematic review (22)Randomized trial (21)Phase 3 study (12)Clinical trial (304)Review article (501)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (84)Case report (42)Commentary or editorial (37)Retracted Publication (4) Only studies currently recruiting participants (27)

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Publications and studies (1912)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Extracellular Vesicles for HD (2024-12-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Huntington's Disease and Pain (2024-11-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases (2024-11-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical Study to Monitor Plasma Levels of 24OHC in Subject with HD (2024-11-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's Disease (2024-10-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prospective Huntington At Risk Observational Study (2024-09-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biological Sample Collection for Research and Biobanking (2024-08-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease Progression (2024-05-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Huntington's Disease Young Adult Study 2.0 (2024-04-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions (2024-04-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prospective Single-Timepoint Huntington's Disease Biospecimen Collection Study (2024-04-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Oral Nutritional Supplement Effect on HDL Function (2024-03-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's Disease (2024-03-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort (2024-02-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Characterization and Quantification of Motor Speech Disorders in Huntington's Disease: Identification of Acoustic Markers (2024-02-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects (2024-01-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Long Term Follow-up Grafted Huntington's Disease Patients (2024-01-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease (2024-01-05) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Unusual Presentation of Primary Pulmonary Sarcomatous Cancer With Brain Metastasis: A Case Report. (2023/12/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Lipid Metabolic Disorders in Neurodegenerative Diseases - Role of Androgen Receptor. (2023/12/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans. (2023/12/28) ♡
• Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington's disease. (2023/12/26) ♡
• baz-2 enhances systemic proteostasis in vivo by regulating acetylcholine metabolism. (2023/12/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Global burden of sleep disturbances among older adults and the disparities by geographical regions and pandemic periods. (2023/12/23) ♡
• The Role of Innovation Technology in the Rehabilitation of Patients Affected by Huntington's Disease: A Scoping Review. (2023/12/22) ♡
• Towards interpretable speech biomarkers: exploring MFCCs. (2023/12/21) ♡
• Imaging the neurovascular unit in health and neurodegeneration: a scoping review of interdependencies between MRI measures. (2023/12/21) ♡
• Computer simulations predict the impact of neuronal atrophy on the calcium dynamics in Huntington's disease. (2023/12/20) ♡
• Global Burden of Cardiovascular Diseases and Risks, 1990-2022. (2023/12/19) ♡
• Filipin complex-reactive brain lesions: a cautionary tale. (2023/12/19) ♡
• Complementary insights into corticostriatal synapse loss and cognition in Huntington's disease. (2023/12/19) ♡
• A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system. (2023/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metabolomics: An Emerging "Omics" Platform for Systems Biology and Its Implications for Huntington Disease Research. (2023/12/18) ♡
• Factors Influencing the Total Functional Capacity Score as a Critical Endpoint in Huntington's Disease Research. (2023/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gut-Brain Axis Deregulation and Its Possible Contribution to Neurodegenerative Disorders. (2023/12/16) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rodent Models of Huntington's Disease: An Overview. (2023/12/16) ♡
• Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin. (2023/12/15) ♡
• Neurophysiological hallmarks of Huntington's disease progression: an EEG and fMRI connectivity study. (2023/12/15) ♡
• Machine learning to identify risk factors associated with the development of ventilated hospital-acquired pneumonia and mortality: implications for antibiotic therapy selection. (2023/12/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective. (2023/12/13) ♡
• Expanding horizons of tandem repeats in biology and medicine: Why 'genomic dark matter' matters. (2023/12/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial Quality Control via Mitochondrial Unfolded Protein Response (mtUPR) in Ageing and Neurodegenerative Diseases. (2023/12/13) ♡
• Tandem MutSβ binding to long extruded DNA trinucleotide repeats underpins pathogenic expansions. (2023/12/13) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Rare Presentation of Small Bowel Perforation Secondary to Microscopic Metastasis of Non-small Cell Lung Cancer (NSCLC): A Case Report. (2023/12/12) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. The ubiquitin thioesterase YOD1 ameliorates mutant Huntingtin induced pathology in Drosophila. (2023/12/11) ♡
• The Angiopoietin Signaling Pathway Is Involved in Inflammatory Processes in Hospitalized COVID-19 Patients. (2023/12/08) ♡
• Revisiting the outcome of adult wild-type Htt inactivation in the context of HTT-lowering strategies for Huntington's disease. (2023/12/07) ♡
• Digital gait markers to potentially distinguish fragile X-associated tremor/ataxia syndrome, Parkinson's disease, and essential tremor. (2023/12/07) ♡
• Subthalamic nucleus shows opposite functional connectivity pattern in Huntington's and Parkinson's disease. (2023/12/06) ♡
• Comparative Application of Terminal Restriction Fragment Analysis Tools to Large-Scale Genomic Assays. (2023/12/06) ♡

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