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Huntington's disease
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Publications and studies (1912)
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's Disease (2025-03-10) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. IMarkHD: in Vivo Longitudinal Imaging of HD Pathology (2025-03-05) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases (2025-03-04) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. NYSCF Scientific Discovery Biobank (2025-03-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of MBF-015 in Huntington's Disease Patients (2025-03-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers (2025-02-28) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy of Deutetrabenazine to Control Symptoms of Dysphagia Associated with HD (2025-02-27) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease (2025-02-25) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Early Biomarkers in Premanifest Huntington's Disease Gene Carriers: a Pilot Study (2025-01-20) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria (2025-01-17) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Neurobiological Predictors of Huntington's Disease (PREDICT-HD) (2025-01-14) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest Stage I or Stage II Huntington's Disease (2025-01-03) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Decoding TDP-43: the molecular chameleon of neurodegenerative diseases. (2024/12/31) ♡
- Impact of Upper Limb Function on Activities of Daily Living and Quality of Life in Huntington's Disease. (2024/12/31) ♡
- Current Status and Future Perspective of Seoul National University Hospital-Dementia Brain Bank with Concordance of Clinical and Neuropathological Diagnosis. (2024/12/31) ♡
- Risdiplam utilization, adherence, and associated health care costs for patients with spinal muscular atrophy: a United States retrospective claims database analysis. (2024/12/30) ♡
- Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease. (2024/12/30) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sigma 1 Receptor and Its Pivotal Role in Neurological Disorders. (2024/12/30) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. "A patent review on arachidonic acid lipoxygenase (LOX) inhibitors for the treatment of neurodegenerative diseases (2018-present)". (2024/12/27) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Biodistribution and dosimetry of the PET radioligand [(18)F]CHDI-650 in mice for detection of mutant huntingtin aggregates. (2024/12/27) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Acute Hepatitis B Infection in a Patient With Confirmed Immunity on Long-Acting Cabotegravir/Rilpivirine. (2024/12/27) ♡
- Huntingtin interactome reveals huntingtin role in regulation of double strand break DNA damage response (DSB/DDR), chromatin remodeling and RNA processing pathways. (2024/12/27) ♡
- AI-Powered Neurogenetics: Supporting Patient's Evaluation with Chatbot. (2024/12/27) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A narrative review of phase III and IV clinical trials for the pharmacological treatment of Huntington's disease in adults. (2024/12/27) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Calcium Signalling in Neurological Disorders, with Insights from Miniature Fluorescence Microscopy. (2024/12/25) ♡
- Synergistic combination therapy with ONC201 or ONC206, and enzalutamide or darolutamide in preclinical studies of castration-resistant prostate cancer. (2024/12/25) ♡
- QOMIC: quantum optimization for motif identification. (2024/12/24) ♡
- Smoking timing, genetic susceptibility, and the risk of incident atrial fibrillation: a large prospective cohort study. (2024/12/23) ♡
- A supercritical oil extract of Schisandra chinensis seeds ameliorates Huntington's disease-like symptoms and neuropathology: the potential role of anti-oxidant and anti-inflammatory effects. (2024/12/23) ♡
- Impact of Total Body Surface Area Burn Injuries on Clinical Outcomes and Comorbidities in Elderly Patients Aged Over 65. (2024/12/23) ♡
- Modeling and correction of protein conformational disease in iPSC-derived neurons through personalized base editing. (2024/12/21) ♡
- Glutamine missense suppressor transfer RNAs inhibit polyglutamine aggregation. (2024/12/21) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pharmacogenomics for neurodegenerative disorders - a focused review. (2024/12/20) ♡
- Preserved social facilitation and preferential processing of partner-relevant information in Huntington's disease. (2024/12/19) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Thymidine Phosphorylase Promotes Abdominal Aortic Aneurysm via VSMC Modulation and Matrix Remodeling in Mice and Humans. (2024/12/18) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanisms and Potential Benefits of Neuroprotective Agents in Neurological Health. (2024/12/18) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Cutaneous Plasmacytosis: A Rare Dermatological Condition Mimicking Systemic Plasma Cell Disorders. (2024/12/18) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Evaluation of Anti-Angiogenic Therapy Combined with Immunotherapy and Chemotherapy as a Strategy to Treat Locally Advanced and Metastatic Non-Small-Cell Lung Cancer. (2024/12/17) ♡
- Bridging Huntington's disease research with big data science: Harmonized neuroimaging datasets from multiple studies. (2024/12/16) ♡
- Circulating dimethylguanidino valeric acid, dietary factors, and risk of coronary heart disease. (2024/12/14) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Search for a Universal Treatment for Defined and Mixed Pathology Neurodegenerative Diseases. (2024/12/14) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Frequency, characteristics, and immunological accompaniments of ataxia in anti-NMDAR antibody-associated encephalitis. (2024/12/13) ♡
- The joint memory effect: challenging the selfish stigma in Huntington's disease? (2024/12/09) ♡
- Burden of disease scenarios by state in the USA, 2022-50: a forecasting analysis for the Global Burden of Disease Study 2021. (2024/12/07) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Calcium Ions in the Physiology and Pathology of the Central Nervous System. (2024/12/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Impact of Mast Cell Activation on Neurodegeneration: A Potential Role for Gut-Brain Axis and Helicobacter pylori Infection. (2024/12/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. New perspective on central nervous system disorders: focus on mass spectrometry imaging. (2024/12/05) ♡
- Evaluation of an Antisense Oligonucleotide Targeting CAG Repeats: A Patient-Customized Therapy Study for Huntington's Disease. (2024/12/04) ♡
- Per- and polyfluoroalkyl substances, apolipoproteins and the risk of coronary heart disease in US men and women. (2024/12/03) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Epigenetic Modifiers: Exploring the Roles of Histone Methyltransferases and Demethylases in Cancer and Neurodegeneration. (2024/12/03) ♡
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