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Chronic kidney disease, stage 4-5

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level evidence only (171)Meta-analysis (31)Treatment guideline (9)Randomized controlled trial (79)Systematic review (35)Phase 3 study (17)Clinical trial (146)Review article (468)Early-stage study (phase 1 or 2) (13)Case description (154)Laboratory or animal research (105)Commentary or editorial (59)Retracted Publication (4) Studies currently recruiting participants only (55)

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Publications and studies (2797)

• Taohong Siwu Decoction relieves renal fibrosis: based on network pharmacology and experimental confirmation. (2025/12/01) ♡
• Effects of Shenkang for chronic kidney disease: a propensity score matched with network pharmacology analysis. (2025/12/01) ♡
• Effects of cultural-artistic rehabilitation activities on quality of life, anxiety and depression, and self-management level of maintenance hemodialysis: A propensity-score-matched study. (2025/12/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Efficacy and safety of Chaihuang Tongluo oral liquid in patients with chronic kidney disease: A single-center, randomized, open-label, controlled trial. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Natural Compounds as Nephroprotective Agents: Therapeutic Potential Against Drug-Induced Kidney Injury. (2025/12/01) ♡
• Protective mechanisms of Qingda granule in hypertensive kidney injury: Focus on ERK/RSK1-mediated mitochondrial protection. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Traditional Chinese medicine understanding and treatment strategies for diuretic resistance]. (2025/12/01) ♡
• Nutritional risk screening and analysis of factors influencing nutritional risk in patients with stable chronic obstructive pulmonary disease. (2025/12/01) ♡
• Novel obesity biomarkers as mortality predictors in individuals with CKD: a comparative analysis with traditional anthropometric measures. (2025/12/01) ♡
• Global and China trends in glomerulonephritis-induced chronic kidney disease: health inequities, risk factors and projections to 2050. (2025/12/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. The effect of teriparatide on fracture union in rats with chronic kidney disease. (2025/12/01) ♡
• The burden of extrahepatic organ failures in European patients with cirrhosis. (2025/12/01) ♡
• Observational study of nailfold capillaroscopy features in hypertension, diabetes Mellitus, stroke, and chronic kidney disease: Associations and potential for early detection in cardiovascular and metabolic disorders. (2025/12/01) ♡
• Comparative ex vivo 7T MRI study of renal microstructural changes in cats with and without chronic kidney disease. (2025/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. [Acute Kidney Injury in the Context of Chronic Kidney Disease: Interdisciplinary Aspects]. (2025/12/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. [Treatment, outcomes, and management strategy for purulent pyelonephritis: a systematic review and meta-analysis. Part II]. (2025/12/01) ♡
• FoxO1/PINK1/Parkin-dependent mitophagy mediates the chondroprotective effect of Guzhi Zengsheng Zhitong decoction in osteoarthritis. (2025/11/25) ♡
• Bupi Yishen formula against chronic kidney injury via Akkermansia muciniphila mediated group 3 innate lymphoid cells activation to repair intestinal barrier funciton. (2025/11/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Potential pathways for natural active ingredients to intervene in diabetic kidney disease: targeting macrophage infiltration. (2025/11/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging Role of Calycosin in Inflammatory Diseases: Molecular Mechanisms and Potential Therapeutic Applications. (2025/11/22) ♡
• Network pharmacology and molecular docking analysis of Yishenqingzhuo oral liquid for chronic kidney disease. (2025/11/21) ♡
• Intradialytic exercise: a controlled nationwide effectiveness-implementation study. (2025/11/21) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Microcephalic Osteodysplastic Primordial Dwarfism Type II. (2025/11/20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Frailty and associated factors among older patients with non-dialysis chronic kidney disease: a multicenter cross-sectional study in three hospitals in Yaounde, Cameroon. (2025/11/18) ♡
• Dietary sodium reduction and blood pressure: a dose-response meta-analysis in hypertensive and chronic kidney disease patients. (2025/11/17) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Efficacy and Safety of Oral Antidiabetic Drugs in People with Diabetes and Chronic Kidney Disease: A Systematic Review. (2025/11/15) ♡
• A Report on Nephropathic Cystinosis in Iran- A Scoping Review. (2025/11/15) ♡
• Examining the Association between Oxidative Stress Markers and the Severity of Symptoms in Individuals with COVID-19 and Healthy Individuals. (2025/11/15) ♡
• Bioinformatics analysis for Taohe Chengqi Decoction in treating diabetic kidney disease and cutaneous pruritus based on the theory of "same treatment for different diseases". (2025/11/14) ♡
• [Exploration on the treatment of chronic fatigue syndrome with acupuncture and moxibustion based on the "body-qi-mind trinity life view"]. (2025/11/12) ♡
• A Systematic Review Evaluating Estimated GFR Performance in South Asian Populations. (2025/11/12) ♡
• Predictors of Surgical Success in Parathyroidectomy: A Retrospective Study of Patients Receiving Renal Replacement Therapy with Secondary Hyperparathyroidism. (2025/11/10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mendelian randomization analysis of gut microbiota and chronic kidney disease: Implications for herbal interventions. (2025/11/07) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Low protein diet with personalized support in advanced chronic kidney disease: association with disease progression, dialysis delay and mortality. (2025/11/07) ♡
• Shengqing Jiangzhuo Capsule Alleviates Intestinal Inflammation in Chronic Kidney Disease by Downregulating CHAC1 to Inactivate the HIF-1 Pathway. (2025/11/06) ♡
• Long-Term Survival and Mortality Predictors of Off-Pump vs On-Pump Coronary Artery Bypass Grafting: A 25-Year Cohort Study. (2025/11/05) ♡
• Progression in adult patients with early-stage chronic kidney disease attending tertiary hospitals in Dodoma, Tanzania: prospective longitudinal study. (2025/11/04) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Chinese Herbal Medicine in the Treatment of Chronic Kidney Disease: A Narrative Review of Mechanisms and Therapeutic Potential. (2025/11/04) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Elucidating the Mechanism of Liver and Kidney Damage in Rats Caused by Exposure to 2,4-Dichlorophenoxyacetic Acid and the Protective Effect of Lycium barbarum Polysaccharides Based on Network Toxicology and Molecular Docking. (2025/11/03) ♡
• Effect of Tofogliflozin on Skeletal Muscle Mitochondrial Function in Male Diabetic Mice With Muscle Atrophy. (2025/11/03) ♡
• Abdominal Arterial Calcification Score-Association With Patient Survival Post Kidney Transplant. (2025/11/01) ♡
• Prevalence of metabolic dysfunction-associated steatotic liver disease and fibrosis defined by liver elastography in the United States using National Health and Nutrition Examination Survey 2017-March 2020 and August 2021-August 2023 data. (2025/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Clinical Application of Chinese Herbal Medicine in Small Animal Practice. (2025/11/01) ♡
• Formononetin, a bioactive isoflavone compound in modified nuanxinkang, alleviates cardiorenal syndrome type 4-induced mitochondrial dysfunction by targeting Hippo-YAP signaling. (2025/11/01) ♡
• Shenqi Wan inhibits cellular senescence to alleviate renal fibrosis by modulating the AQP1/TGF-β1/ITPR1 axis. (2025/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Effects of Yoga and naturopathic intervention on cardiac autonomic functions in chronic kidney disease with coronary artery disease - A Case Series. (2025/11/01) ♡
• [Mechanism of Buyang Huanwu Decoction and Didang Decoction in treatment of chronic kidney disease based on ATF6/TXNDC5-regulated "macrophage-myofibroblast transformation" pathway]. (2025/11/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Nutrition at the Crossroads of Diabetes and Kidney Health: Reflections on the 2025 Diabetes Canada Chronic Kidney Disease Guideline From the Lens of a Registered Dietitian. (2025/11/01) ♡
• Epigenetic Role of Gastrointestinal Microbiota in Individuals Receiving Hemodialysis. (2025/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Challenges in cadaveric skin graft survival in organ transplant recipients on immunosuppressive regimens: a case report. (2025/11/01) ♡

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