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Chronic kidney disease, stage 4-5
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Publications and studies (2755)
- Long-term mortality and risk of chronic kidney disease in children following severe malaria complicated by acute kidney injury: a prospective observational study. (2027/05/19) ♡
- Zhenwu Decoction ameliorates experimental benign prostatic hyperplasia: association with mitochondrial quality control, oxidative stress and apoptosis regulation. (2027/01/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The role of gut microbiome in aging-associated diseases: where do we stand now and how technology will transform the future. (2026/12/31) ♡
- Molecular mechanism of Yishen Qingzhuo oral liquid in treating chronic renal failure via the Nrf2/HO-1-mediated ferroptosis pathway. (2026/12/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Yi-Shen-Hua-Shi granule added to supportive care reduces proteinuria in IgA nephropathy: a multicenter randomized controlled trial. (2026/12/01) ♡
- Illness perception and insomnia among patients with maintenance hemodialysis: a moderated mediation model of fear of progression and self-compassion. (2026/12/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Adherence to the Mediterranean diet and its effects on the onset and progression of diabetic nephropathy: a systematic review. (2026/12/01) ♡
- Integrative multi-omics analysis identifies VCAN and ESM1 as candidate cell-type-associated biomarkers of NET-related glomerular injury in diabetic kidney disease. (2026/12/01) ♡
- Pill burden and health-related quality of life across dialysis modalities: a multimodal assessment using KDQOL-36 and eQ-5D-5L. (2026/12/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Real-world effectiveness of central dialysis fluid delivery system (CDDS) in maintenance hemodialysis: a retrospective multicenter study. (2026/12/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Calciphylaxis in chronic kidney disease: a systematic review of pathomechanisms and risk factors for calcific uremic arteriolopathy. (2026/12/01) ♡
- Ginkgo biloba extract GBE50 alleviates vascular calcification through inhibiting the NF-κB pathway and the NLRP3 inflammasome. (2026/10/28) ♡
- Mechanistic elucidation of the therapeutic effects of Fushen Xiezhuo formula on chronic kidney disease. (2026/10/28) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Comment on "Comparison of ChatGPT-3.5, ChatGPT-4.0 and DeepSeek in generating dietary plans for patients with chronic kidney disease: A focus on nutritional accuracy and dietary inflammation". (2026/10/01) ♡
- Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho. (2026/10/01) ♡
- Niaoduqing particles ameliorated tubulointerstitial fibrosis by suppressing IκB/NF-κB signalling pathway via inhibiting host- and gut microbiota-mediated tryptophan co-metabolism. (2026/10/01) ♡
- Epidemiology of glomerular diseases in Northeastern Brazil from 2008-2024. (2026/10/01) ♡
- Qing'e Pill extract attenuates vascular calcification and improves renal dysfunction in chronic kidney disease mice by modulating calcium-phosphorus homeostasis and downregulating the expression of Runx2/OCN. (2026/09/15) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Discovery of anti-renal fibrosis quality markers from Piperis longi fructus: An integrated strategy of hollow fibre cell trapping method coupled with liquid chromatography-mass spectrometry and in vitro efficacy verification. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Beyond Glycemia in T1D: The Hidden Burden of Insulin Resistance and Cardiorenal Risk in Type 1 Diabetes-Part 1. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current State of Cardiorenal Disease in People with Type 1 Diabetes. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Central Sleep Apnea in Renal and Endocrine Disease. (2026/09/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Identification of anti-fibrotic components of Bofutsushosan under conditions of age-associated obesity in mice. (2026/09/01) ♡
- Serum and Urine Metabolite Profiling Combined With Network Pharmacology to Predict the Renoprotective Mechanism of Huangkui Capsule Against Acute Kidney Injury. (2026/09/01) ♡
- Shen-Gu-Mai-Kang Formula alleviates CKD-associated vascular calcification by suppressing VSMC osteogenic transdifferentiation via the Sfrp2/β-catenin signaling. (2026/09/01) ♡
- Beraprost Attenuates Starvation-Induced Apoptosis and Protects Feline Endothelial Cells. (2026/09/01) ♡
- Metabolomics-Defined Subtypes of Prediabetes and Risk of Cardiovascular-Kidney-Metabolic Outcomes. (2026/08/10) ♡
- Interfacial Engineering of Printable MOF/MXene Heterostructured Inks for High-Performance Wearable Ammonia Sensors. (2026/08/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The gut-kidney axis revisited: Integrating gut microbiota, autophagy and metabolomics in chronic kidney disease. (2026/08/10) ♡
- A cross-regional initiative for improving type 2 diabetes mellitus care quality measurement in Spain - The Diabetes Lighthouse project. (2026/08/10) ♡
- Genetic and pharmaceutical targeting of Suv39h1 ameliorates renal fibrosis by unlocking CXCL10 transcription. (2026/08/10) ♡
- Bifid triple viable tablets are associated with renal biochemical improvement and qualitative gastrointestinal changes in 5/6-nephrectomized rats: An exploratory microbiome-metabolome study. (2026/08/10) ♡
- Pedal Arch and Angiosome Classification Combined with the Wound, Ischaemia, and foot Infection Staging System for Prediction of Limb Amputation and Wound Healing in Chronic Limb-Threatening Ischemia: A Prospective Cohort Study. (2026/08/10) ♡
- The HFpEF-ABA Score, Incident Heart Failure, and Finerenone in Chronic Kidney Disease with Type 2 Diabetes. (2026/08/10) ♡
- Burden of Systemic Inflammation Among Individuals with Atherosclerotic Cardiovascular Disease and Chronic Kidney Disease in Northern China. (2026/08/10) ♡
- Wuling San ameliorates renal fibrosis through modulating S1PR2 activation and suppressing the RhoA/ROCK pathway in adenine-induced chronic kidney disease. (2026/08/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Traditional Chinese medicine as a therapeutic option for cerebral small vessel disease: treatment outcomes and potential mechanisms. (2026/08/10) ♡
- Network pharmacology and experimental verification reveal the mechanism of hederagenin in suppressing podocyte injury in focal segmental glomerular sclerosis. (2026/08/10) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Vitamin D status and supplementation in left ventricular remodeling in chronic kidney disease: A systematic review and meta-analysis. (2026/08/10) ♡
- Osteoporotic fracture, diagnostic activity, and treatment in patients with gout. (2026/08/10) ♡
- Correction to: Time-lapse HR-pQCT reliably assesses and monitors local bone turnover in patients with chronic kidney disease. (2026/08/10) ♡
- Exosomes in kidney disease: From Pathophysiology to Diagnostic and Therapeutic Tools. (2026/08/10) ♡
- Dynamic patterns of thyroid hormones and incident chronic kidney disease: evidence from 18 years of follow-up in the Tehran Thyroid Study. (2026/08/10) ♡
- Prognostic value of risk factors for ischaemic and major bleeding events in chronic coronary syndrome: a SWEDEHEART registry study. (2026/08/10) ♡
- Factors associated with selection of total hip arthroplasty versus hemiarthroplasty for femoral neck fracture in older adults: a nationwide analysis of 99,084 cases. (2026/08/10) ♡
- Difelikefalin Treatment in Chronic Kidney Disease-Associated Pruritus: Modelling Infection-Related Hospitalisation Cost Offsets Using Trial and Real-World Data Across Seven European Countries. (2026/08/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gallstones and acute cholecystitis in CKD and dialysis: an underrecognized biliary burden in nephrology. (2026/08/10) ♡
- Prevalence, Incidence and Mortality of Chronic Kidney Disease in Type 1 and Type 2 Diabetes-A Nationwide Danish Register-Based Cohort Study. (2026/08/09) ♡
- Association between glomerular filtration rate and comprehensive geriatric assessment parameters in older adults. (2026/08/09) ♡
- Incident chronic kidney disease risk and the predictive value of the uric acid-to-HDL ratio in lean and non-lean MASLD: a prospective cohort and multi-omics study. (2026/08/09) ♡
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