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Chronic hepatitis B

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (82)Meta-analysis (26)Treatment guideline (6)Randomized trial (32)Systematic review (10)Phase 3 study (8)Clinical trial (630)Review article (169)Early study (phase 1 or 2) (25)Case reports (96)Laboratory or animal research (16)Commentary or Editorial (50)Retracted publication (2) Studies currently recruiting participants only (31)

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Publications and studies (2004)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The clinical significance and optimization strategies of HBeAg seroclearance in chronic hepatitis B treatment. (2026/06/29) ♡
• Chronic Hepatitis B in the Asia-Pacific Region: Results of the 2023 Global Burden of Disease Study. (2026/06/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Short-chain Fatty Acids and Bile Acids Signaling in Chronic Hepatitis B. (2026/06/28) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Letter to the Editor: Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study. (2026/06/28) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update. (2026/06/27) ♡
• Impact of Gene Polymorphism rs2275913 and Serum IL-17A Levels on Liver Fibrosis Severity Across the Natural History of Chronic Hepatitis B in Indonesia. (2026/06/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. HBx-Associated Reactivation of the IGF2 Locus in Chronic HBV Infection and HBV-Related Hepatocarcinogenesis: Evidence Boundaries and Biomarker Implications. (2026/06/25) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. [Clinical study on the efficacy of Wuling capsules combined with nucleos (t) ide analogues in the treatment of low-level viremia patients with chronic hepatitis B]. (2026/06/20) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. An Incidental Echoic Finding of Double Inferior Vena Cava in an Asymptomatic Patient: A Case Report. (2026/06/19) ♡
• Safety and HBsAg reduction with a lentiviral vaccine J-51 in chronic hepatitis B: An investigator-initiated pilot trial. (2026/06/18) ♡
• Hepatoprotective effects of modified Yiguanjian decoction in pregnant patients with chronic hepatitis B. (2026/06/15) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Secondary spontaneous pneumothorax due to extensive pulmonary tuberculosis in a patient with acute hepatitis B flare: clinical challenges and therapeutic decision making-a case report. (2026/06/14) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Effectiveness of Digital Health Interventions to Improve Self-Care in Patients With Chronic Diseases: Systematic Review and Meta-Analysis of Randomized Controlled Trials. (2026/06/09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Impact of Fatigue on Patient-Reported Outcomes and Work Productivity in Chronic Hepatitis B and C: Insights From a Multinational Registry Study. (2026/06/01) ♡
• Altered renal disposition of adefovir in metabolic dysfunction-associated steatohepatitis using the fast-food diet and thioacetamide-induced model to extrapolate renal secretion. (2026/06/01) ♡
• Angiotensin-Converting Enzyme Inhibitors and Hepatocellular Carcinoma Risk in Patients With Chronic Hepatitis B and Hypertension: A Nationwide Dose-Response Cohort Study. (2026/05/15) ♡
• Duodenal metastasis of hepatocellular carcinoma following multimodal therapy: a rare case report and literature review. (2026/05/13) ♡
• Evaluating the antiviral efficacy of Azadirachta indica and Moringa oleifera against hepatitis B and C: Implications for alternative therapeutic approaches. (2026/05/01) ♡
• Integrated routine laboratory indices for risk stratification in HBV-related cirrhosis: a real-world study. (2026/05/01) ♡
• Neu5Gc-associated Serum Immunoglobulin G Glycosylation as a Diagnostic Biomarker for Hepatocellular Carcinoma. (2026/04/28) ♡
• Diagnostic Accuracy of Prognostic Nutritional Index and Systemic Immune-Inflammatory Index in Predicting Fibrosis and Histological Activity in Chronic Hepatitis B. (2026/04/23) ♡
• Vitamin D deficiency in chronic hepatitis B across the disease spectrum: association with viral activity rather than hepatocellular carcinoma. (2026/04/11) ♡
• A liver gene signature links liver cancer risk in chronic viral hepatitis to intrahepatic IgA plasma cells. (2026/04/01) ♡
• Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. AASLD ISDA Practice Guideline on treatment of chronic hepatitis B. (2026/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Functional cure for chronic hepatitis B: A state of immune control over cccDNA persistence. (2026/04/01) ♡
• Younger age predicts increased HBsAg loss in children with chronic hepatitis B on antiviral therapy: A systematic review and meta-analysis. (2026/04/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Effects of a culturally tailored intervention on medication adherence in Chinese and Vietnamese Americans with hepatitis B: a randomized controlled trial. (2026/03/31) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Letter to the Editor: Prevalence and Risk Factors of Significant Hepatic Fibrosis in Omani Patients with HBeAg-negative Chronic Hepatitis B Virus Infection: A Retrospective Study. (2026/03/31) ♡
• Fatty Liver and Pancreatic Steatosis in Patients with Chronic Hepatitis B and C and Wilson's Disease. (2026/03/23) ♡
• Single-cell hepatitis B sequencing reveals distinct viral infection events consistent with superinfection. (2026/03/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Adefovir dipivoxil-induced hypophosphatemic osteomalacia and osteoporosis: a case report and literature review. (2026/03/17) ♡
• Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. Consensus document on the diagnosis, management, and treatment of chronic hepatitis B virus and hepatitis D virus infection in Spain. (2026/03/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Hepatitis B virus functional cure in persons with HIV: what are the predictors and which novel markers are useful? (2026/03/01) ♡
• Novel mechanism of Guizhi Jia Huangqi decoction disrupting HBV lifecycle via Camp/PKC/PKB axis beyond NTCP blockade. (2026/03/01) ♡
• Traditional and Novel Virologic Markers for Functional Cure and HBeAg Loss with Pegylated Interferon in Chronic Hepatitis B: A Systematic Review and Meta-analysis. (2026/02/28) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Rapid Drug-Induced Granulomatous Dermatitis to Amlodipine. (2026/02/15) ♡
• Proteomics Insight into the Pathogenic Evolution of Chronic Hepatitis B across Distinct Clinical Stages. (2026/02/06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Paired liver-spleen high-frequency ultrasound deep learning network for full-stage liver fibrosis classification and clinical benefit compared with 2D-SWE in chronic hepatitis B cohort: a prospective multicenter study. (2026/02/01) ♡
• Social determinants disadvantage score and liver health in the All of Us Research Program. (2026/02/01) ♡
• Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. ALEH position statement on the management of hepatitis B virus infection 2025. (2026/01/30) ♡
• Biejia-Ruangan enhances the efficacy of entecavir in reversing liver cirrhosis in patients with chronic HBV infection: A seven-year open-label follow-up cohort study. (2026/01/30) ♡
• Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study. (2026/01/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Aflatoxin and Liver Cancer in China: The Evolving Research Landscape. (2026/01/25) ♡
• Predicting loss of hepatitis B surface antigen and evaluating the durability of functional cure induced by pegylated interferon alpha: insights from a real-world study. (2026/01/21) ♡
• Serum N-glycan NA3Fb identified as a prognostic biomarker of poor outcome in HBV-related hepatocellular carcinoma. (2026/01/20) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Intracranial hepatitis B virus (HBV) infection following intracerebral hemorrhage in a patient with seronegative occult HBV infection. (2026/01/20) ♡
• Combined therapy with the estrogen receptor ERα and IFNα-2b suppresses HBV replication by inducing GBP1 expression. (2026/01/16) ♡
• Functional immune responses induced by a capsid assembly modulator in chronic hepatitis B virus-infected humanized mice. (2026/01/14) ♡
• Mitochondrial metabolic remodeling predicts therapeutic response to PegIFN-α in chronic hepatitis B. (2026/01/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current status and challenges of therapeutic targets, novel drugs and delivery systems for hepatitis B: how far to our goal? (2026/01/14) ♡

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