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Acute lymphoblastic leukemia

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (55)Meta-analysis (18)Treatment guideline (2)Systematic review (17)Randomized trial (11)Phase 3 study (7)Clinical trial (621)Review article (170)Early study (phase 1 or 2) (30)Description of individual patients (210)Laboratory or animal study (36)Commentary or editorial (47)Retracted publication (2)Concerns have been raised (1) Studies currently seeking participants only (43)

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Publications and studies (2052)

• The effect of Yarrowia lipolytical-asparaginase on apoptosis induction and inhibition of growth in Burkitt's lymphoma Raji and acute lymphoblastic leukemia MOLT-4 cells. (2020/03/01) ♡
• Fluorescence spectral detection of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML): A novel photodiagnosis strategy. (2020/03/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Dexamethasone and neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia. (2020/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Microbiota changes in a pediatric acute lymphocytic leukemia mouse model. (2020/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Identification of RNPC3 as a novel JAK2 fusion partner gene in B-acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib. (2020/03/01) ♡
• Early immune stimulation and childhood acute lymphoblastic leukemia in Costa Rica: A comparison of statistical approaches. (2020/03/01) ♡
• Coagulopathy in cytogenetically and molecularly distinct acute leukemias at diagnosis: Comprehensive study. (2020/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Osteonecrosis of the talus of a child with acute lymphoblastic leukemia: A case report. (2020/03/01) ♡
• Depression following graft-versus-host disease in a patient with acute lymphoblastic leukaemia: A case report. (2020/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Could PCSK9 be a new therapeutic target of Eugenol? In vitro and in silico evaluation of hypothesis. (2020/03/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Bariatric interventions in obesity treatment and prevention in pediatric acute lymphoblastic leukemia: a systematic review and meta-analysis. (2020/03/01) ♡
• Evaluation of diet as a risk factor in the development of childhood leukaemia: a case control study. (2020/03/01) ♡
• Nutritional status and appetite-regulating hormones in early treatment of acute lymphoblastic leukemia among children and adolescents: a cohort study. (2020/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Clinical actionability of measurable residual disease (MRD) assessment in the management of patients with hematologic malignancies: a case-based monograph. (2020/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Assessment of measurable residual disease (MRD) in adult patients with acute lymphocytic leukemia: best use and a case report. (2020/03/01) ♡
• Huai Qi Huang Potentiates Dexamethasone-Mediated Lethality in Acute Lymphoblastic Leukemia Cells by Upregulating Glucocorticoid Receptor α. (2020/02/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Relapsed/refractory early T-cell precursor acute lymphoblastic leukemia was salvaged by venetoclax plus HAG regimen. (2020/02/01) ♡
• Cord blood stem cell derived CD16(+) NK cells eradicated acute lymphoblastic leukemia cells using with anti-CD47 antibody. (2020/02/01) ♡
• Antitumor effect of baicalin from the Scutellaria baicalensis radix extract in B-acute lymphoblastic leukemia with different chromosomal rearrangements. (2020/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Chimeric antigen receptor T cells in solid tumors: a war against the tumor microenvironment. (2020/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Terminal deoxynucleotidyl transferase negative B-lymphoblastic leukaemia/lymphoma with CD138 expression. (2020/02/01) ♡
• Pharmacogenetic Variants in MTHFR Gene are Significant Predictors of Methotrexate Toxicities in Bangladeshi Patients With Acute Lymphoblastic Leukemia. (2020/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Precision medicine for human cancers with Notch signaling dysregulation (Review). (2020/02/01) ♡
• Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152 in vivo and in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway. (2020/02/01) ♡
• Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells. (2020/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The European Medicines Agency Review of Kymriah (Tisagenlecleucel) for the Treatment of Acute Lymphoblastic Leukemia and Diffuse Large B-Cell Lymphoma. (2020/02/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Bovine Colostrum Against Chemotherapy-Induced Gastrointestinal Toxicity in Children With Acute Lymphoblastic Leukemia: A Randomized, Double-Blind, Placebo-Controlled Trial. (2020/02/01) ♡
• Profile of anemia in acute lymphoblastic leukemia patients on maintenance therapy and the effect of micronutrient supplementation. (2020/02/01) ♡
• Melatonin rescued methotrexate-induced spatial deficit and hyperhomocysteinemia and increased asymmetric dimethylarginine in plasma and dorsal hippocampus in developing rats. (2020/02/01) ♡
• High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia. (2020/01/24) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Genetic Signature of Acute Lymphoblastic Leukemia and Netherton Syndrome Co-incidence-First Report in the Literature. (2020/01/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Drug Resistance Biomarkers and Their Clinical Applications in Childhood Acute Lymphoblastic Leukemia. (2020/01/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia. (2020/01/09) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Treatment with anti CD19 chimeric antigen receptor T cells after antibody-based immunotherapy in adults with acute lymphoblastic leukemia. (2020/01/01) ♡
• BCR/ABL preleukemic fusion gene in subpopulations of hematopoietic stem and progenitor cells from human UCB. (2020/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Acute Lymphoblastic Leukemia in a Child Presenting Primarily with Priapism. (2020/01/01) ♡
• Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells. (2020/01/01) ♡
• Prognostic significance of the tumor suppressor protein p53 gene in childhood acute lymphoblastic leukemia. (2020/01/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Emerging Effects of Sepantronium Bromide (YM155) on MOLT-4 Cell Line Apoptosis Induction and Expression of Critical Genes Involved in Apoptotic Pathways. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Flow Cytometric Minimal Residual Disease Analysis in Acute Leukemia: Current Status. (2020/01/01) ♡
• Serum Methotrexate Level and Side Effects of High Dose Methotrexate Infusion in Pediatric Patients with Acute Lymphoblastic Leukaemia (ALL). (2020/01/01) ♡
• Cluster of Differentiation 96 in Children with Acute Leukemia: A Single Center Cohort Study. (2020/01/01) ♡
• Priapism in Childhood B-Cell Acute Lymphoblastic Leukemia: A Rare Presentation. (2020/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Whole-exome sequencing reveals the subclonal expression of NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia. (2020/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prevalence of vitamin D deficiency in childhood acute lymphoblastic leukemia and its association with adverse outcomes during induction phase of treatment. (2020/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Trends in age- and sex-adjusted body mass index and the prevalence of malnutrition in children with cancer over 42 months after diagnosis: a single-center cohort study. (2020/01/01) ♡
• The cost-effectiveness of pegaspargase versus native asparaginase for first-line treatment of acute lymphoblastic leukaemia: a UK-based cost-utility analysis. (2019/12/29) ♡
• KCTD15 is overexpressed in human childhood B-cell acute lymphoid leukemia. (2019/12/27) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Beat pediatric ALL MRD: CD28 CAR T and transplant. (2019/12/26) ♡
• Therapy-related acute lymphoblastic leukemia is a distinct entity with adverse genetic features and clinical outcomes. (2019/12/23) ♡

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