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Sickle cell disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the most robust evidence (78)Meta-analysis (14)Treatment guideline (2)Randomized trial (30)Systematic review (27)Phase 3 study (5)Clinical trial (630)Review article (208)Early study (phase 1 or 2) (15)Case report (141)Laboratory or animal research (19)Commentary or editorial (54)Retracted publication (2) Studies currently recruiting participants only (32)

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Publications and studies (2099)

• The Critical Need for Pooled Data on Coronavirus Disease 2019 in African Children: An AFREhealth Call for Action Through Multicountry Research Collaboration. (2021/11/16) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sickle Cell Disease: Thoughts for India From the Jamaican Cohort Study. (2021/11/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Systematic Review on Nonopioid Pharmacologic Treatments for Chronic Pain: Surveillance Report 1: Literature Update Period: September 2019 through September 2021. (2021/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mutual Pan-African support paradigm to produce scientific evidence of traditional medical practices for use against COVID-19 and emerging pandemics. (2021/11/01) ♡
• Analyzing Effects of Sickle Cell Disease on Morphometric and Cranial Growth in Indian Population. (2021/11/01) ♡
• Altered type 1 interferon responses in alloimmunized and nonalloimmunized patients with sickle cell disease. (2021/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Spontaneous epidural hematoma: A case report of rare crisis of sickle cell disease. (2021/11/01) ♡
• Profiling of 35 Cases of Hb S/Hb E (HBB: c.20A>T/HBB: c.79G>a), Disease and Association with α-Thalassemia and β-Globin Gene Cluster Haplotypes from Odisha, India. (2021/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A retrospective case study of successful translational research: Gazelle Hb variant point-of-care diagnostic device for sickle cell disease. (2021/10/25) ♡
• Haptoglobin Gene Polymorphism among Sickle Cell Patients in West Cameroon: Hematological and Clinical Implications. (2021/10/20) ♡
• APOL1 Renal Risk Variants and Sickle Cell Trait Associations With Reduced Kidney Function in a Large Congolese Population-Based Study. (2021/10/12) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hemoglobin life-threatening value (1.9 g/dl) in good general condition: a pediatric case-report. (2021/10/07) ♡
• Homozygous sickle cell disease related mortality in Senegal (2011-2020). (2021/10/04) ♡
• Autoimmune Liver Disease in Patients With Sickle Cell Disease. (2021/10/01) ♡
• Oxidative stress, malaria, sickle cell disease, and innate immunity. (2021/10/01) ♡
• Retained Splenic Function in an Indian Population with Homozygous Sickle Cell Disease May Have Important Clinical Significance. (2021/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Improving Outcomes for Patients With Sickle Cell Disease in the United States: Making the Case for More Resources, Surveillance, and Longitudinal Data. (2021/10/01) ♡
• Dose- and Sex-Dependent Changes in Hemoglobin Oxygen Affinity by the Micronutrient 5-Hydroxymethylfurfural and α-Ketoglutaric Acid. (2021/09/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature. (2021/09/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer, Infectious Diseases and Sickle Cell Anemia. (2021/09/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Effects of Treatment with Blood Transfusion, Iron Chelation and Hydroxyurea on Puberty, Growth and Spermatogenesis in Sickle Cell Disease (SCD): A short update. (2021/09/02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Risk factors for CKD stage II onset in a prospective cohort of homozygous sickle cell adults. (2021/09/01) ♡
• Aggravated Dental and Periodontal Status in Patients with Sickle Cell Disease and Its Association with Serum Ferritin. (2021/09/01) ♡
• Prevalence of sickle cell trait and its association to renal dysfunction among blood donors at University of Medical Sciences Teaching Hospital, Ondo, Nigeria. (2021/09/01) ♡
• Timed Average Mean Maximum Velocity (TAMMV) of Cerebral Blood Flow of Children and Adolescents with Sickle cell Disease: correlation with clinical and hematological profiles in country. (2021/09/01) ♡
• [Disease genotype, haplotypes, diagnosis and associated studies in sickle cell anemia]. (2021/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanism and Applications of CRISPR/Cas-9-Mediated Genome Editing. (2021/08/21) ♡
• A Randomized Clinical Hypnosis Pilot Study: Improvements in Self-Reported Pain Impact in Adults with Sickle Cell Disease. (2021/08/19) ♡
• Burden of disease among the world's poorest billion people: An expert-informed secondary analysis of Global Burden of Disease estimates. (2021/08/16) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Association and Risk Factors of Osteonecrosis of Femoral Head in Sickle Cell Disease: A Systematic Review. (2021/08/04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A feasibility study of telemedicine for paediatric sickle cell patients living in a rural medically underserved area. (2021/08/01) ♡
• Reduced global cerebral oxygen metabolic rate in sickle cell disease and chronic anemias. (2021/08/01) ♡
• Biomarkers of clinical severity in treated and untreated sickle cell disease: a comparison by genotypes of a single center cohort and African Americans in the NHANES study. (2021/08/01) ♡
• Hidradenitis suppurativa is associated with iron deficiency anemia, anemia of chronic disease, and sickle cell anemia-A single-center retrospective cohort study. (2021/07/26) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Liver transplantation for sickle cell disease: a systematic review. (2021/07/01) ♡
• Use of herbal medicine by caregivers in the management of children with sickle cell disease in Mulago National Referral Hospital - Uganda. (2021/07/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Response to: Acute Liver Failure in a Sickle Cell Patient. (2021/07/01) ♡
• The impact of body mass index on left ventricular mass index, right ventricular function, and cardiac dimension of children with sickle cell anemia in Enugu City. (2021/07/01) ♡
• Sickle Cell Disease and Psychosocial Well-Being: Comparison of Patients With Preclinical and Clinical Avascular Necrosis of the Femoral Head. (2021/07/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A mutant fibrinogen that is unable to form fibrin can improve renal phenotype in mice with sickle cell anemia. (2021/06/15) ♡
• Hemodynamic and biological correlates of glomerular hyperfiltration in sickle cell patients before and under renin-angiotensin system blocker. (2021/06/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Adverse outcome of acute splenic sequestration crisis in pregnancy. (2021/06/01) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Transfusion management of severe anaemia in African children: a consensus algorithm. (2021/06/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sleep Deficiency and Pediatric Chronic Pain. (2021/06/01) ♡
• Relationship between disease severity and folate status of children with sickle cell anaemia in Enugu, South East Nigeria. (2021/06/01) ♡
• Nutritional and Hematological Status of Sudanese Women of Childbearing Age with Steady-state Sickle Cell Anemia. (2021/05/31) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Dietary ω-3 Fatty Acid Supplementation Improves Murine Sickle Cell Bone Disease and Reprograms Adipogenesis. (2021/05/18) ♡
• FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice. (2021/05/11) ♡
• Mechanisms of pain in sickle cell disease. (2021/05/01) ♡
• Impact of COVID-19 on vasooclusive crisis in patients with sickle cell anaemia. (2021/05/01) ♡

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