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Systemic amyloidosis
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Publications and studies (1226)
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Assessment of the Efficacy and Safety of Injectable TQB2934 (Subcutaneous Injection) in Systemic Light Chain Amyloidosis Patients (2026-05-08) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study of AT-02 in Subjects With Systemic Amyloidosis. (2026-05-06) ♡
- Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome (2026-04-22) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis (2026-04-13) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Italian Transthyretin Amyloidosis Web-Network (2026-03-27) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Rapid dFLC Response Predict CHR in AL Amyloidosis (2026-03-09) ♡
- Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. A Study to Evaluate the Safety and Efficacy of SCTC21C in Combination With Bortezomib, Cyclophosphamide, and Dexamethasone in Patients With Newly Diagnosed Systemic Light-Chain Amyloidosis (NDSLCA) (2026-02-05) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant (2026-01-28) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Diagnostic challenge of systemic amyloidosis mimicking EGFR-TKI toxicity in lung adenocarcinoma: a case report. (2025/12/31) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Myopathies Associated With Monoclonal Gammopathies of Clinical Significance: A Narrative Review. (2025/12/30) ♡
- Prevalence estimation of a rare disease with the French National Rare Disease Registry: example of TNF receptor associated periodic syndrome (TRAPS). (2025/12/29) ♡
- Symptom course of PFAPA syndrome. (2025/12/29) ♡
- Bladder Amyloidosis With Pulmonary Lesions: A Case of Spontaneous Remission After Transurethral Resection. (2025/12/28) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Nodular pulmonary amyloidosis presenting as a localized manifestation of lymphoproliferative disease: A three-case series. (2025/12/26) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Left Atrial Reservoir Strain in Cardiovascular and Systemic Disease: Advances and Clinical Applications From Physiology to Practice. (2025/12/25) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Interplay Between Rheumatoid Arthritis and Chronic Kidney Disease: From Mechanisms to Treatment. (2025/12/23) ♡
- Clinical significance of t(11;14) translocation in systemic AL amyloidosis in the era of daratumumab therapy. (2025/12/22) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Surgical Treatment of Primary Localized Cutaneous Nodular Amyloidosis of the Nose: Resection and Reconstruction With a Nasolabial Flap. (2025/12/22) ♡
- Evolving treatments and outcomes in patients with newly diagnosed multiple myeloma undergoing autologous stem cell transplantation: a real-world study in China. (2025/12/19) ♡
- Cryo-EM structure of renal AL amyloid fibrils from a patient with λ1 light chain amyloidosis. (2025/12/17) ♡
- Structure of ATTRv-F64S fibrils isolated from skin tissue of a living patient. (2025/12/16) ♡
- Intracellular aggregation of the transthyretin protein is limited by Hsp70 chaperones. (2025/12/16) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Dermatological Manifestations of Amyloid Light-Chain (AL) Amyloidosis: A Case Report Highlighting Early Diagnosis and Treatment. (2025/12/15) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Imaging Features of Amyloid of the Breast: Review of 94 Cases From the Literature and 6 New Cases. (2025/12/13) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Renal gelsolin amyloidosis as a rare cause of proteinuria: a case report and literature review. (2025/12/12) ♡
- Clinical and genetic analysis of a family with transthyretin amyloid polyneuropathy caused by a TTR Lys55Asn mutation. (2025/12/12) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Progressive Fibrosis in Hydroxychloroquine Cardiomyopathy Mimicking Hypertrophic Cardiomyopathy and Cardiac Amyloidosis. (2025/12/10) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Intraocular amyloidosis presenting with secondary glaucoma: a clinical-pathologic report and literature review. (2025/12/09) ♡
- Structural and molecular homogeneity of ATTRv-T60A amyloid fibrils across patients and organs. (2025/12/04) ♡
- Effects of Hydration on Transthyretin Conformational Dynamics and Oligomerization. (2025/12/02) ♡
- Risk of Systemic Manifestations in Homozygous Carriers of the Transthyretin V142I Variant: A Million Veteran Program Analysis. (2025/12/02) ♡
- Serum free light chain level-based and non-fixed cycle daratumumab treatment strategy for patients with light chain amyloidosis. (2025/12/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Systemic amyloid A amyloidosis in a captive Cape hyrax (Procavia capensis). (2025/12/01) ♡
- Impact of early minimal residual disease assessment on the outcomes of patients with systemic light chain amyloidosis. (2025/12/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Generation of integration-free human induced pluripotent stem cell line MUi040-A derived from CD34 + hematopoietic stem cells of a patient with constitutional pericentric inversion of chromosome 9. (2025/12/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyloid Light Chain Proteins in Cardiovascular Disease: Pathogenesis and Emerging Therapies for Cardiac Amyloidosis. (2025/12/01) ♡
- Endoscopic Diagnosis and Clinical Course of Isolated Upper Gastrointestinal Amyloidosis: A Retrospective Observational Study. (2025/12/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Renal AA amyloidosis following COVID-19 infection. (2025/11/28) ♡
- Nodular amyloid deposits with collagen fibre rupture in tenosynovial carpal tissues are associated with transthyretin cardiomyopathy: a single-centre prospective diagnostic study. (2025/11/28) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Amyloid A Amyloidosis Secondary to Thymoma. (2025/11/28) ♡
- Proving Bone Marrow Plasma Cell Clonality by Flow Cytometry: An Important Tool in the Diagnosis of Immunoglobulin Light-Chain Amyloidosis. (2025/11/28) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Inflammatory Role of Serum Amyloid A in the Pathogenesis and Progression of Diabetic Nephropathy. (2025/11/27) ♡
- Comparative analysis of conventional and novel inflammatory biomarkers in Familial Mediterranean fever during attack-free periods. (2025/11/25) ♡
- Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. Laboratory Workup of Amyloidosis. (2025/11/24) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The heart-brain axis: unraveling the interconnections between cardiovascular and Alzheimer's diseases. (2025/11/24) ♡
- Glycosidic scaffold bearing multiple galloyl moieties from pomegranate disrupts transthyretin amyloids. (2025/11/21) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Predictors of relapse after withdrawing biotherapies in children with inactive juvenile idiopathic arthritis: a retrospective cohort study of the JIR cohort. (2025/11/20) ♡
- More Than Just a Plaque: A Diagnostic Challenge in a Case of Suspected Cutaneous Localized Nodular Amyloidosis. (2025/11/20) ♡
- Twin Diseases in Different Organs: A Cautionary Tale of Anchoring on a Positive Scan. (2025/11/18) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Diffuse Cutaneous Systemic Sclerosis Complicated by Serum Amyloid A Protein Cardiac Amyloidosis and Cardiogenic Shock. (2025/11/17) ♡
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