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Sickle cell disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the most robust evidence (78)Meta-analysis (14)Treatment guideline (2)Randomized trial (30)Systematic review (27)Phase 3 study (5)Clinical trial (630)Review article (208)Early study (phase 1 or 2) (15)Case report (141)Laboratory or animal research (19)Commentary or editorial (54)Retracted publication (2) Studies currently recruiting participants only (32)

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Publications and studies (2099)

• Clinical and laboratory parameters, risk factors predisposing to the development of priapism in sickle cell patients. (2020/01/01) ♡
• [Role of OCT-angiography in the management of sickle cell retinopathy]. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging drugs in randomized controlled trials for sickle cell disease: are we on the brink of a new era in research and treatment? (2020/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Sickle Cell Intrahepatic Cholestasis with Acute Liver Failure and Acute Kidney Injury: Favourable Outcome with Exchange Transfusion. (2020/01/01) ♡
• Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments. (2020/01/01) ♡
• Physical Activity and Pain in Youth With Sickle Cell Disease. (2020/01/01) ♡
• Effects of oxidative stress on liver, brain and spinal cord of rats using L-NAME and treated with hydroxyurea. A model of sickle cell complication. (2020/01/01) ♡
• Rethinking Rideshares: A Transportation Assistance Pilot for Pediatric Patients with Sickle Cell Disease. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metabolic Triggers of Invariant Natural Killer T-Cell Activation during Sterile Autoinflammatory Disease. (2020/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mortality and Hospitalizations among Sickle Cell Disease Patients with End-Stage Kidney Disease Initiating Dialysis. (2020/01/01) ♡
• Methylene tetrahydrofolate reductase gene mutation in sickle cell anaemia patients in Lagos, Nigeria. (2019/12/30) ♡
• Effectiveness of Nurse Led Intervention on Health Related Quality of Life among Children with Sickle Cell Disease in Oman: A Pilot Study. (2019/12/28) ♡
• The Effects of Hydroxyurea Therapy on the Six-Minute Walk Distance in Patients with Adult Sickle Cell Anemia: An Echocardiographic Study. (2019/12/27) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Abdominal pain in a patient with sickle cell disease with multiple complications. (2019/12/25) ♡
• An Educational Study Promoting the Delivery of Transcranial Doppler Ultrasound Screening in Paediatric Sickle Cell Disease: A European Multi-Centre Perspective. (2019/12/24) ♡
• Neutrophils remain detrimentally active in hydroxyurea-treated patients with sickle cell disease. (2019/12/23) ♡
• Altered HDL particle in sickle cell disease: decreased cholesterol content is associated with hemolysis, whereas decreased Apolipoprotein A1 is linked to inflammation. (2019/12/20) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Beneficial effects of endurance exercise training on skeletal muscle microvasculature in sickle cell disease patients. (2019/12/19) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Translating exercise benefits in sickle cell disease. (2019/12/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Massive Extradural Hematoma in Sickle Cell Disease and the Importance of Rapid Neuroimaging. (2019/12/18) ♡
• Severity of Anaemia Has Corresponding Effects on Coagulation Parameters of Sickle Cell Disease Patients. (2019/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Scavenger Receptor Class B type 1 (SR-B1) and the modifiable risk factors of stroke. (2019/12/17) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Treatment of dental complications in sickle cell disease. (2019/12/16) ♡
• Use of an automated pyrosequencing technique for confirmation of sickle cell disease. (2019/12/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rational Drug Design of Peptide-Based Therapies for Sickle Cell Disease. (2019/12/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Wide-field imaging of sickle retinopathy. (2019/12/12) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Interdisciplinary assessment and management of a patient with a fibrous gingival enlargement of unknown origin: A case report. (2019/12/12) ♡
• End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. (2019/12/10) ♡
• End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain. (2019/12/10) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Study Evaluates Rapid Sickle Cell Disease Test. (2019/12/10) ♡
• Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice. (2019/12/10) ♡
• Comparison between Adult Patients with Sickle Cell Disease of Sub-Saharan African Origin Born in Metropolitan France and in Sub-Saharan Africa. (2019/12/09) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. A Meta-Analysis on the Seroprevalence of Parvovirus B19 among Patients with Sickle Cell Disease. (2019/12/09) ♡
• Establishing care for sickle cell disease in western Kenya: achievements and challenges. (2019/12/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hydroxyurea-induced cutaneous squamous cell carcinoma: A case report. (2019/12/06) ♡
• Impact of A Six Week Training Program on Ventilatory Efficiency, Red Blood Cell Rheological Parameters and Red Blood Cell Nitric Oxide Signaling in Young Sickle Cell Anemia Patients: A Pilot Study. (2019/12/05) ♡
• Gender-Related Differences in Sickle Cell Disease in a Pediatric Cohort: A Single-Center Retrospective Study. (2019/12/05) ♡
• Hemorheological Alterations and Oxidative Damage in Sickle Cell Anemia. (2019/12/04) ♡
• Severe childhood anemia and emergency blood transfusion in Gadarif Hospital, eastern Sudan. (2019/12/03) ♡
• International Differences in Outpatient Pain Management: A Survey of Sickle Cell Disease. (2019/12/03) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gene therapy for blood diseases. (2019/12/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Differences in lung function between children with sickle cell anaemia from West Africa and Europe. (2019/12/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Self-care deficits in women with leg ulcers and sickle cell disease. (2019/12/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. The role of hydroxyurea to prevent silent stroke in sickle cell disease: Systematic review and meta-analysis. (2019/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Red Blood Cells: Exchange, Transfuse, or Deplete. (2019/12/01) ♡
• Enhancing Pain Assessment in Pediatric Sickle Cell Disease by Applying Quality Improvement Science. (2019/12/01) ♡
• KNOWLEDGE, ATTITUDE AND USE OF HYDROXYUREA AMONG ADULT SICKLE CELL DISEASE PATIENTS. (2019/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Spontaneous Intracranial Extradural Hematoma Secondary to Hypofibrinogenemia: A Rare Case Report. (2019/11/25) ♡
• Vaso-occlusive crises in patients with sickle cell disease: Parents' perspectives and association with disease outcomes. (2019/11/25) ♡
• Data on the role of miR-144 in regulating fetal hemoglobin production in retinal pigmented epithelial cells. (2019/11/23) ♡

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