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Sickle cell disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest quality evidence only (77)Meta-analysis (14)Treatment guideline (2)Randomized trial (30)Systematic review (27)Phase 3 study (4)Clinical trial (631)Review article (208)Early study (phase 1 or 2) (15)Case report (141)Laboratory or animal research (19)Commentary or editorial (53)Retracted publication (2) Only studies currently recruiting participants (29)

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Publications and studies (2096)

• Teen With Sickle Cell Disease, Headache and Forehead Swelling. (2026/06/11) ♡
• Human papillomavirus genotypes and factors associated with major cervical smear abnormalities in a sickle cell endemic area of Kisangani, Democratic Republic of the Congo. (2026/06/10) ♡
• Alloimmunization in sickle cell disease: Addressing an ongoing clinical challenge. (2026/06/05) ♡
• Sickle cell disease 115 years later: improving health outcomes through policy, research, and collaboration, to achieve health equity. (2026/06/03) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. The GLOBE Trial: Efficacy and Safety of L-Glutamine Plus Hydroxyurea Versus Hydroxyurea Alone in Sickle Cell Anemia - A Double-Blind, Randomized Study. (2026/06/01) ♡
• Factors associated with hemoglobin response to hydroxyurea in patients with sickle cell disease. (2026/06/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Serial Imaging and Burnout Transition of Extramedullary Hematopoiesis in Sickle Beta-thalassemia: A Two-year Case Study. (2026/06/01) ♡
• Non-pharmacological interventions for managing sickle cell crisis pain: A qualitative study on adolescents' and caregivers' experiences. (2026/06/01) ♡
• Diagnostic relevance of osteocalcin and bone alkaline phosphatase as markers of bone turnover in Sickle Cell Anaemia: A Zaria study. (2026/06/01) ♡
• ß-Globin gene cluster haplotypes in Moroccan sickle cell disease patients: diversity pilot study. (2026/06/01) ♡
• Advancing child health: forecasting the next great research achievements. (2026/05/30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Nutritional status and clinical severity in children with sickle cell disease and confirmed asthma: a multicentre observational study. (2026/05/19) ♡
• Prevalence of Low Bone Mineral Density Increases With Age in Sickle Cell Disease. (2026/05/18) ♡
• Factors associated with anemia among adolescent girls in Western India: insights from a multi-centric cross-sectional study. (2026/05/18) ♡
• Association Between Micronutrients and Cognitive Performance Among Adolescents and Young Adults Living With Sickle Cell Disease in Kumasi, Ghana: A Cross-Sectional Study. (2026/05/15) ♡
• Anemia Among Hospitalized Children in a Ghanaian Pediatric Emergency Unit: A Prospective Observational Study of Prevalence, Associated Factors, and Hematologic Patterns. (2026/05/10) ♡
• Acute erythroblastopenia due to Parvovirus B19 in hemoglobinopathies: a retrospective case series at Ibn Sina Hospital, Rabat, Morocco. (2026/05/06) ♡
• [Care pathway for children with sickle cell disease admitted to the pediatric emergency department at the Cocody University Hospital (Abidjan, Ivory Coast) from January to December 2024]. (2026/05/04) ♡
• Impact of Extramedullary Disease at Diagnosis on Outcomes Post Allogeneic Hematopoietic Cell Transplant in Children and Young Adults With Acute Myeloid Leukemia: A CIBMTR Report. (2026/05/01) ♡
• The Correlation of Anti-phospholipid Antibodies, Anti-cyclic Citrullinated Peptide Antibody, Anti-nuclear Antibodies with Hematological Inflammatory Markers and Clinical Manifestations in Sickle Cell Disease During Steady State Phase. (2026/05/01) ♡
• Correlation Between Serum Lactate Dehydrogenase Levels and Pain Severity in Vaso-Occlusive Crises Among Sickle Cell Anemia Patients: A Cross-Sectional Study. (2026/05/01) ♡
• Predictors of Cerebrovascular Accident Among Sudanese Children with Sickle Cell Anemia. (2026/05/01) ♡
• Compound Heterozygosity for Hemoglobin S and D-Punjab: An Interplay of Two Haemoglobinopathies/Rare Mimic of Sickle Cell Disease. (2026/05/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. "The Soft Skull Secret- Unveiling Soft Head Syndrome in Sickle Cell Anemia". (2026/05/01) ♡
• Low Hemoglobin Is not Always Iron Deficiency Anemia-A Cross-Sectional Study in a Tribal Community in the Nilgiris, Tamil Nadu. (2026/05/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Clinician Assessment for Acute Chest Syndrome in Febrile Children With Sickle Cell Disease Revisited. (2026/05/01) ♡
• Medically Unnecessary Venipuncture in Autism Spectrum Disorder Behavior Assessments. (2026/05/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Risk factors associated with disease severity among children hospitalised with community-acquired pneumonia in Angola. (2026/04/30) ♡
• Comparative analysis of serum vitamin D and haematological parameters among paediatric sickle cell and non-sickle cell patients at a teaching hospital in Accra, Ghana: a case-control study. (2026/04/29) ♡
• Interdisciplinary Pediatric Long-COVID Care: A Descriptive Study of Interventions and Health-Related Quality of Life. (2026/04/10) ♡
• Evidence-Based Management of Sickle Cell Disease: Ethnobotanical Survey and Laboratory Validation of Traditional Herbal Recipes. (2026/04/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A case of SCD controlled by IMiDs and hydroxyurea. (2026/04/01) ♡
• Mental health challenges associated with sickle cell disease and strategies to address them: Reflections from a community input panel. (2026/04/01) ♡
• Low Use of FDA-Approved Medications for Sickle Cell Disease in Adults. (2026/04/01) ♡
• Proteomic Analysis of Golden Sputum Reveals Pulmonary Complement Activation During Acute Chest Syndrome in Children With Sickle Cell Disease. (2026/04/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Anti-IL-18 immunotherapy decreases inflammatory and vaso-occlusive responses in mice with sickle cell disease. (2026/04/01) ♡
• Loss of energy homeostasis contributes to hepatic damage development in sickle cell disease. (2026/04/01) ♡
• Implications of changes in WHO haemoglobin elevation adjustment guidelines on global, regional, and national anaemia burden, 1990-2023: a population-based modelling study. (2026/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Perioperative Anemia and Coagulopathy Management in Pediatric Patients with Medical Complexity. (2026/04/01) ♡
• Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. (2026/04/01) ♡
• Haemoglobinopathies and health disparities: findings of a large-scale sample survey among indigenous populations in Odisha, India. (2026/03/27) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exploring the Relationship Between Angiogenesis Inhibition of sFLT-1 and Sickle Cell Nephropathy. (2026/03/26) ♡
• Comparative multitarget vaso-protective effects of brown and black Vigna unguiculata (L.) walp extracts: Evidence of stronger modulation of sickle cell pathophysiology by the brown variety. (2026/03/25) ♡
• Prevalence and Risk Factors of Anemia in Pregnant Women Attending Antenatal Clinic at a Medical Center in Accra, Ghana: A Cross-Sectional Study. (2026/03/15) ♡
• A mixed-methods evaluation to optimize the existing hospital based sickle cell disease care model from a tribal area of Gujarat, India. (2026/03/13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. MULTIsite feasibility of MUSIc therapy to address Quality Of Life in Sickle cell disease (MULTI-MUSIQOLS): protocol for a mixed-methods randomised controlled trial at two US medical centres. (2026/03/09) ♡
• Nasopharyngeal Microbiome Composition and its Clinical Correlates in Children Hospitalized with Severe Pneumonia in East Africa. (2026/03/03) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Quantitative Volumetric Analysis of the Brain Using Magnetic Resonance Imaging in Sickle Cell Anaemia. (2026/03/02) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Plasma Exchange and Eculizumab Treatment of a Child With Sickle Cell Disease, Severe Intravascular Hemolysis, Macrophage Activation, and Multiple Organ Failure. (2026/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Synergistic Potential of Thalidomide and Hydroxyurea in Sickle Cell Disease Management: A Promising Combination Therapy. (2026/03/01) ♡

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