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Liver, kidneys and digestion
Primary sclerosing cholangitis
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Publications and studies (1451)
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biobank for Cholestatic Liver Diseases. (2026-02-17) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC) (2026-02-04) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC) (2026-01-23) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis (2026-01-14) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Liver Cirrhosis Network Cohort Study (2026-01-13) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Gluten-free Diet in PSC and IBD (2026-01-08) ♡
- Protocol for fabricating a vascularized bile duct-on-a-chip. (2025/12/31) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. MAIT Cells in Liver Disease. (2025/12/31) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Quality and Quantity? The Clinical Significance of Myosteatosis in Various Liver Diseases: A Narrative Review. (2025/12/28) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Drug-induced liver injury in inflammatory bowel disease: Challenges in diagnosis and monitoring. (2025/12/27) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Graves' disease with autoimmune hepatitis and primary sclerosing cholangitis: an overlap syndrome. (2025/12/26) ♡
- Proteome-scale autoantibody profiling in PSC: Associations with clinical phenotypes and evidence for neuroendocrine deregulations. (2025/12/23) ♡
- Proctocolectomy with permanent ileostomy is associated with improved transplant-free survival in patients with PSC. (2025/12/22) ♡
- RIPK1 inhibition reduces biliary injury and fibrosis in primary sclerosing cholangitis. (2025/12/19) ♡
- Elevated Epithelial Splicing Regulatory Protein 1 Expression in Biliary Atresia Indicates Its Potential as a Molecular Marker. (2025/12/19) ♡
- Risk factors for autoimmune liver disease recurrence after liver transplantation. (2025/12/18) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Beyond futility: The history and potential of liver transplantation in cholangiocarcinoma. (2025/12/18) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Exploring the biliary microbiome in hepatopancreatobiliary disorders: a comprehensive systematic review of microbial signatures and diagnostic potential. (2025/12/17) ♡
- A novel cell-permeable LOXL2 inhibitor PAT-1251 potently suppresses biliary liver fibrosis via collagen crosslinking-dependent and -independent mechanisms. (2025/12/12) ♡
- Burden of primary sclerosing cholangitis in Sweden (2002-2020): Incidence, outcomes, healthcare utilization, and costs. (2025/12/12) ♡
- Pruritus and health-related quality of life in chronic liver disease: a longitudinal, survey-based cohort study. (2025/12/11) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pembrolizumab-Induced Secondary Cholangitis: A Case Report. (2025/12/06) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Drug-Induced Sclerosing Cholangitis Leading to Discontinuation of Treatment in a Patient with Metastatic Breast Cancer: A Case Report. (2025/12/06) ♡
- Complementary use of autoantibody detection methods facilitates diagnosis of juvenile autoimmune hepatitis and autoimmune sclerosing cholangitis. (2025/12/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. CD40 Ligand Deficiency. (2025/12/04) ♡
- From Isolation to Information: Launching an Online Community for Patients with Primary Sclerosing Cholangitis, Primary Biliary Cholangitis, and Autoimmune Hepatitis in Romania-A Descriptive Study. (2025/12/02) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical Profile and Predictors of Repeated Relapse in Type 1 Autoimmune Pancreatitis: A Multicenter Observational Study. (2025/12/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Dietary and Lifestyle Risk Factors in Primary Sclerosing Cholangitis: In Search of Mechanistic Explanations and Health Improvement. (2025/12/01) ♡
- Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. Autoimmune hepatitis in children: Guidelines of the Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ISPGHAN). (2025/12/01) ♡
- Prevalence and Outcomes of Primary Sclerosing Cholangitis in Inflammatory Bowel Disease: A Multinational Study Across Asia. (2025/12/01) ♡
- Triple autoimmune overlap syndrome of the liver: a rare case of concomitant PBC, PSC, and AIH. (2025/12/01) ♡
- Radial laser ablation under cholangioscopic guidance for a tight intrahepatic bile duct stricture caused by primary sclerosing cholangitis. (2025/12/01) ♡
- Biliary Reconstruction in Liver Transplantation with Primary Sclerosing Cholangitis: Roux-en-Y Hepaticojejunostomy or Duct-to-Duct Anastomosis? (2025/12/01) ♡
- Secondary Sclerosing Cholangitis in a Critically Ill Burn Patient: A Case Report and Review of the Literature. (2025/11/30) ♡
- Cultured bacteria isolated from primary sclerosing cholangitis patient bile induce inflammation and cell death. (2025/11/25) ♡
- Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis. (2025/11/25) ♡
- Systemic PCSK9 elevation characterises autoimmune liver disease across sexes. (2025/11/21) ♡
- Nebokitug, an Anti-chemokine (C-C Motif) Ligand 24 Monoclonal Antibody, in Patients With Primary Sclerosing Cholangitis: A Phase 2 Study. (2025/11/19) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good's Syndrome). (2025/11/17) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Lipoprotein X-Induced Hyperlipidemia Following Liver Transplantation in the Setting of Persistent Cholestasis and Antibody-Mediated Rejection. (2025/11/17) ♡
- Numb-exon3 and full length Numb equivalently alleviate cholestatic liver fibrosis by inhibiting ductular reaction. (2025/11/14) ♡
- Causal mediation of immune cells in autoimmune liver diseases and oral cancer risk: a Mendelian randomization study. (2025/11/14) ♡
- Impact of Metabolic Dysfunction-Associated Steatotic Liver Disease on Fatigue and Pruritus in Primary Sclerosing Cholangitis: A U.S. Single-Center Study. (2025/11/14) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Risk stratification of IBD-associated liver disease using routinely collected biomarkers from a large-scale real-world dataset. (2025/11/13) ♡
- Association between non-invasive biomarkers and quality of life in Primary Sclerosing Cholangitis. (2025/11/12) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanistic roles and therapeutic potential of bacteriophages in inflammatory gastrointestinal diseases. (2025/11/12) ♡
- Tepotinib-Induced Cholangitis in a Patient With Non-Small Cell Lung Cancer: A Case Report. (2025/11/11) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gut-Liver Axis, Microbiota, Bile Acids, and Immune Response in Pathogenesis of Primary Sclerosing Cholangitis: An Overview. (2025/11/03) ♡
- Bile acids engage the SIPR-STAT3 signaling axis to modulate regulatory T cell responses in fibrosing cholangiopathies. (2025/11/01) ♡
- Natural History, Treatment Persistence and Predictors of Treatment Failure in Patients With Ulcerative Colitis on 5-Aminosalicylic Acid: A US Population-Level Cohort Study. (2025/11/01) ♡
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