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Primary sclerosing cholangitis

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (32)Meta-analysis (9)Treatment guideline (7)Phase 3 study (6)Systematic review (6)Randomized trial (4)Clinical trial (182)Review article (287)Early study (phase 1 or 2) (23)Case reports (179)Laboratory or animal study (27)Commentary or editorial (54) Studies currently recruiting participants only (30)

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Publications and studies (1451)

• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Meta-analysis of the association of extraintestinal manifestations with the development of pouchitis in patients with ulcerative colitis. (2019/03/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sex-related factors in autoimmune liver diseases. (2019/03/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial. (2019/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Reverse rendezvous with endoscopic retrograde cholangiography and percutaneous transhepatic cholangio drainage: who meets whom? (2019/03/01) ♡
• Polymorphisms in Natural Killer Cell Receptor Protein 2D (NKG2D) as a Risk Factor for Cholangiocarcinoma. (2019/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice. (2019/03/01) ♡
• Diagnostic performance of quantitative magnetic resonance imaging biomarkers for predicting portal hypertension in children and young adults with autoimmune liver disease. (2019/03/01) ♡
• Loss of Wnt Secretion by Macrophages Promotes Hepatobiliary Injury after Administration of 3,5-Diethoxycarbonyl-1, 4-Dihydrocollidine Diet. (2019/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Inflammation and Neoplasia of the Pouch in Inflammatory Bowel Disease. (2019/02/28) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Immunoglobulin G4-related disease mimicking gallbladder cancer with associated choledochal cyst: A case report of a malignant masquerade. (2019/02/22) ♡
• Pediatric autoimmune liver disease and extra-hepatic immune-mediated comorbidities. (2019/02/01) ♡
• Adherence to ursodeoxycholic acid therapy in patients with cholestatic and autoimmune liver disease. (2019/02/01) ♡
• Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis. (2019/02/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Is This the Last Requiem for Simtuzumab? (2019/02/01) ♡
• Primary Sclerosing Cholangitis and Psychological Wellbeing: A Scoping Review. (2019/02/01) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial. (2019/02/01) ♡
• Diagnostic performance of a stepwise cytological algorithm for biliary malignancy in primary sclerosing cholangitis. (2019/02/01) ♡
• The Impact of Inflammatory Bowel Disease in Canada 2018: Extra-intestinal Diseases in IBD. (2019/02/01) ♡
• Vitamin D non-sufficiency is prevalent in children with chronic liver disease in a tropical country. (2019/02/01) ♡
• Paternal cholestasis exacerbates obesity-associated hypertension in male offspring but is prevented by paternal ursodeoxycholic acid treatment. (2019/02/01) ♡
• Statin Exposure Is Not Associated with Reduced Prevalence of Colorectal Neoplasia in Patients with Inflammatory Bowel Disease. (2019/01/15) ♡
• A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis. (2019/01/10) ♡
• [The gut microbiome is important in chronic liver disease]. (2019/01/07) ♡
• Technical success and outcomes in pediatric patients undergoing transjugular intrahepatic portosystemic shunt placement: a 20-year experience. (2019/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Extrahepatic autoimmunity in autoimmune liver disease. (2019/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Development of mild drug-induced sclerosing cholangitis after discontinuation of nivolumab. (2019/01/01) ♡
• 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Diet: A Rodent Model in Cholestasis Research. (2019/01/01) ♡
• A case of melatonin-induced biochemical flare in a patient with primary sclerosing cholangitis with features of autoimmune hepatitis. (2019/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Inflammatory bowel disease - one entity with many molecular faces. (2019/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Simtuzumab (GS-6624) in the Prevention of Progression of Liver Fibrosis in Adults With Primary Sclerosing Cholangitis (PSC) (2019-10-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Fecal Microbiota Transplantation for the Treatment of Primary Sclerosing Cholangitis. (2019-08-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Repeatability and Reproducibility of Quantitative MRCP (2019-08-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study (2019-08-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Paternally Inherited Phenotypes in Cholestasis (2019-08-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Treatment of IgG4-Related Disease With Revlimid and Rituximab (2019-07-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Gluten-free Diet in Patients With Primary Sclerosing Cholangitis (PSC) (2019-07-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Trial of BTT1023 in Patients With Primary Sclerosing Cholangitis (2019-05-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Vancomycin Treatment in Recurrent PSC in Liver Transplant Patients (2019-03-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing Cholangitis (2019-03-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Leflunomide for Maintenance of Remission in IgG4 Related Disease (2019-03-06) ♡
• The Role of Next Generation Sequencing in the Differential Diagnosis of Caroli's Syndrome. (2018/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Healthy Donor Fecal Microbiota Transplantation for Recurrent Bacterial Cholangitis in Primary Sclerosing Cholangitis - A Single Case Report. (2018/12/28) ♡
• M1-Polarized Macrophages Promote Self-Renewing Phenotype of Hepatic Progenitor Cells with Jagged1-Notch Signalling Involved: Relevance in Primary Sclerosing Cholangitis. (2018/12/24) ♡
• Clinical characteristics and outcomes of primary sclerosing cholangitis and ulcerative colitis in Japanese patients. (2018/12/20) ♡
• Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3(+) Regulatory T Cells. (2018/12/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Fibroinflammatory Liver Injuries as Preneoplastic Condition in Cholangiopathies. (2018/12/04) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pancreatic Cystosis and Intrahepatic Biliopathy in a Young Adult with Cystic Fibrosis. (2018/12/01) ♡
• Primary sclerosing cholangitis leads to dysfunction and loss of MAIT cells. (2018/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Juvenile autoimmune hepatitis: A comprehensive review. (2018/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Autoimmune sclerosing cholangitis: Evidence and open questions. (2018/12/01) ♡

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