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Primary biliary cholangitis

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (95)Meta-analysis (34)Treatment guideline (10)Randomized trial (22)Phase 3 Study (15)Systematic review (14)Clinical examination (354)Review article (274)Early study (phase 1 or 2) (18)Case reports (145)Laboratory or animal study (50)Commentary or editorial (39)Retracted publication (2) Studies currently recruiting participants only (32)

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Publications and studies (1841)

• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Paraneoplastic anti-TIF1 gamma Autoantibody-positive Dermatomyositis as Clinical Presentation of Hepatocellular Carcinoma Recurrence. (2023/02/28) ♡
• Safety and tolerability of obeticholic acid in chronic liver disease: a pooled analysis of 1878 individuals. (2023/02/09) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Role of Red Cell Distribution Width as a Prognostic Marker in Chronic Liver Disease: A Literature Review. (2023/02/09) ♡
• Metabolomic analysis shows dysregulation in amino acid and NAD+ metabolism in palmitate treated hepatocytes and plasma or non-alcoholic fatty liver disease spectrum. (2023/02/05) ♡
• Genetic link between rheumatoid arthritis and autoimmune liver diseases: A two-sample Mendelian randomization study. (2023/02/01) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A prospective multicenter phase II study of FOLFIRINOX as a first-line treatment for patients with advanced and recurrent biliary tract cancer. (2023/02/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Low-dose continuous terlipressin infusion is effective and safer than intravenous bolus injections in reducing portal pressure and control of acute variceal bleeding. (2023/02/01) ♡
• Application of the Latest Advances in Evidence-Based Medicine in Primary Biliary Cholangitis. (2023/02/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease. (2023/02/01) ♡
• Liver-specific deletion of microRNA-34A alleviates ductular reaction and liver fibrosis during experimental cholestasis. (2023/02/01) ♡
• Impact of muscle mass on the prognosis of liver transplantation for infants with biliary atresia. (2023/01/16) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case report: Severe hepatic fibrosis induced by chronic cholestasis of congenital biliary dilation treated by laparoscopic surgery after immunonutrition support- An infantile case. (2023/01/12) ♡
• Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity. (2023/01/09) ♡
• Comprehensive autoantibody profiles in systemic sclerosis: Clinical cluster analysis. (2023/01/04) ♡
• Using two-step cluster analysis to classify inpatients with primary biliary cholangitis based on autoantibodies: A real-world retrospective study of 537 patients in China. (2023/01/04) ♡
• Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis. (2023/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. In Vitro Models for the Study of Liver Biology and Diseases: Advances and Limitations. (2023/01/01) ♡
• Geographical region and clinical outcomes of patients with primary biliary cholangitis from Western Europe. (2023/01/01) ♡
• Epidemiology and updated management for autoimmune liver disease. (2023/01/01) ♡
• Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis. (2023/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. DNA methylation in cell plasticity and malignant transformation in liver diseases. (2023/01/01) ♡
• Liver biopsy in inflammatory bowel disease patients with sustained abnormal liver function tests: a retrospective single-center study. (2023/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. EUS-guided biliary drainage in patients with moderate-severe cholangitis is safe and effective: a multi-center experience. (2023/01/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Neonatal Hepatic Myeloid Progenitors Expand and Propagate Liver Injury in Mice. (2023/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Endothelin Signaling Mediates Biliary-Endothelial Crosstalk in Primary Sclerosing Cholangitis. (2023/01/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Safety, tolerability, pharmacokinetics and pharmacodynamics of a novel farnesoid X receptor (FXR) agonist-TQA3526 in healthy Chinese volunteers: a double-blind, randomized, placebo-controlled, dose-escalation, food effect phase I study. (2023/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of Cilofexor in Adults With Primary Sclerosing Cholangitis (2023-11-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of [14C]CS0159 in China Healthy Subjects (2023-11-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (2023-10-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases (2023-10-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Subcutaneous Doses of CM-101 as a Treatment for Medical Conditions Involving Inflammatory and Fibrotic Mechanisms in Healthy Male Subjects (2023-09-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluation of the Safety and Efficacy of HK-660S in Patients With Primary Sclerosing Cholangitis (2023-07-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis (2023-07-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus (2023-07-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Detection Program for Patients With Primary Biliary Cholangitis Lost in the System (2023-06-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prospective, Multicenter Cohort Study on Primary Biliary Cholangitis (2023-06-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. PSC Clinical Epidemiology in China (2023-05-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS0159 in Chinese Healthy Subjects (2023-05-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. UDCA in the Treatment of COVID-19 Infection and Its Clinical Prognosis in Patients With Autoimmune Liver Disease (2023-04-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis (2023-03-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis (2023-03-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis (2023-02-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cholangioscopy in Primary Sclerosing Cholangitis (PSC) (2023-01-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls (2023-01-18) ♡
• Primary biliary cholangitis: personalized medicine for optimal therapeutic opportunities. (2022/12/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Secondary sclerosing cholangitis and IgG4 sclerosing cholangitis - A review of cholangiographic and ultrasound imaging. (2022/12/30) ♡
• An Assessment of the Serum Activity of ADH and ALDH in Patients with Primary Biliary Cholangitis. (2022/12/28) ♡
• Risk Factors for Carbapenem Resistant Gram Negative Bacteria (CR-GNB) Carriage Upon Admission to the Gastroenterology Department in a Tertiary First Class Hospital of China: Development and Assessment of a New Predictive Nomogram. (2022/12/28) ♡
• Outcomes of delayed versus early endoscopic intervention for acute biliary pancreatitis with non-severe acute cholangitis. (2022/12/26) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Progressive Cholestasis and Biliary Cirrhosis After Initiating Oral Semaglutide: Report From the Drug-Induced Liver Injury Network. (2022/12/26) ♡

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