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Polycystic kidney disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (48)Meta-analysis (12)Treatment guideline (1)Randomized trial (17)Phase 3 study (10)Systematic review (8)Clinical trial (242)Review article (250)Early study (phase 1 or 2) (14)Case report (185)Laboratory or animal research (38)Commentary or editorial (45)Retracted publication (1) Studies currently recruiting participants only (33)

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Publications and studies (1435)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Joubert syndrome: Molecular basis and treatment. (2023/02/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Plant-derived compounds for treating autosomal dominant polycystic kidney disease. (2023/02/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Variants in AQP11 may result in autosomal recessive bilateral cystic renal dysgenesis. (2023/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nutrient-sensing mTORC1 and AMPK pathways in chronic kidney diseases. (2023/02/01) ♡
• A SEC61A1 variant is associated with autosomal dominant polycystic liver disease. (2023/02/01) ♡
• Cardiac Manifestations in Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Single-Center Study. (2023/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Development of a Patient-Reported Outcomes Tool to Assess Pain and Discomfort in Autosomal Dominant Polycystic Kidney Disease. (2023/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V(2) Receptor in In Vitro, Ex Vivo, and In Vivo Models of ADPKD. (2023/01/26) ♡
• Activation of tolvaptan-responsive T-cell clones with the structurally-related mozavaptan. (2023/01/15) ♡
• Transcription factor Ap2b regulates the mouse autosomal recessive polycystic kidney disease genes, Pkhd1 and Cys1. (2023/01/12) ♡
• Mechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons. (2023/01/10) ♡
• Novel method for the genomic analysis of PKD1 mutation in autosomal dominant polycystic kidney disease. (2023/01/09) ♡
• Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGF-β(1) signaling. (2023/01/01) ♡
• Regulation of PKD2 channel function by TACAN. (2023/01/01) ♡
• Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease. (2023/01/01) ♡
• Clinical and genetic spectrum from a prototype of ciliopathy: Joubert syndrome. (2023/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Delayed diagnosis of bladder cancer in a patient with autosomal dominant polycystic kidney disease. (2023/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Crystal-Induced Lower GI Necrosis in a Posttransplant Recipient with Diverticular Disease. (2023/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Fluoroscopy and CT Guided Translumbar Tunneled Dialysis Catheter for Hemodialysis Access Failure in a Case of Autosomal Dominant Polycystic Kidney Disease. (2023/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Clinical findings, underlying pathogenetic processes and treatment of vascular dysfunction in autosomal dominant polycystic kidney disease. (2023/01/01) ♡
• Functions of the primary cilium in the kidney and its connection with renal diseases. (2023/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ADPKD Patient Registry (2023-11-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Treat Autosomal Dominant Polycystic Kidney Disease With Oral Ketone Ester? (2023-10-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Clinical Trial of Water Therapy for Autosomal Dominant Polycystic Kidney Disease (2023-10-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. National Registry of Rare Kidney Diseases (2023-10-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Atorvastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease (2023-05-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Roll-over Study to Assess Safety of Lixivaptan in Participants With ADPKD Who Completed Study PA-ADPKD-303 (2023-05-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease (2023-04-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Time Restricted Feeding in Autosomal Dominant Polycystic Kidney Disease (2023-04-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Assessment of Treatment With Laparoscopic Fenestration or Aspiration Sclerotherapy for Large Symptomatic Hepatic Cysts (2023-04-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of the Efficacy and Safety of Tesevatinib in Subjects With ADPKD (2023-02-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease (2023-02-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients (2023-02-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN) (2023-02-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease) (2023-01-03) ♡
• Cyst Fraction as a Biomarker in Autosomal Dominant Polycystic Kidney Disease. (2022/12/31) ♡
• Polycystin-1 Is a Crucial Regulator of BIN1 Expression and T-Tubule Remodeling Associated with the Development of Dilated Cardiomyopathy. (2022/12/30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Automated Kidney and Liver Segmentation in MR Images in Patients with Autosomal Dominant Polycystic Kidney Disease: A Multicenter Study. (2022/12/29) ♡
• A Low-Cost Sequencing Platform for Rapid Genotyping in ADPKD and its Impact on Clinical Care. (2022/12/28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Exome Sequencing of a Clinical Population for Autosomal Dominant Polycystic Kidney Disease. (2022/12/27) ♡
• Tracking N- and C-termini of C. elegans polycystin-1 reveals their distinct targeting requirements and functions in cilia and extracellular vesicles. (2022/12/27) ♡
• Polycystic Kidney Disease Drug Development: A Conference Report. (2022/12/27) ♡
• Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. (2022/12/23) ♡
• Single-Cell and CellChat Resolution Identifies Collecting Duct Cell Subsets and Their Communications with Adjacent Cells in PKD Kidneys. (2022/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. TRPC Channels in the Physiology and Pathophysiology of the Renal Tubular System: What Do We Know? (2022/12/22) ♡
• Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease. (2022/12/22) ♡
• Cross-Species Permissivity: Structure of a Goat Adeno-Associated Virus and Its Complex with the Human Receptor AAVR. (2022/12/21) ♡
• A rare cause of galactorrhea in autosomal dominant polycystic kidney disease: pituitary stalk compression by an intracranial aneurysm. (2022/12/21) ♡
• miR-20a is upregulated in serum from domestic feline with PKD1 mutation. (2022/12/20) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Do renal and cardiac malformations in the fetus signal carnitine palmitoyltransferase II deficiency? A rare lethal fatty acid oxidation defect. (2022/12/19) ♡

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