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Systemic lupus erythematosus (SLE)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (106)Meta-analysis (39)Treatment guideline (2)Systematic review (34)Randomized trial (21)Phase 3 study (10)Clinical trial (609)Review article (373)Early study (phase 1 or 2) (26)Case report (317)Laboratory or animal study (58)Commentary or editorial (40)Retracted publication (3) Studies currently recruiting participants only (37)

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Publications and studies (2475)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Fibroblast Growth Factor 21 in Systemic Lupus Erythematosus (2025-02-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of SCTB35 in Patients with Systemic Lupus Erythematosus (2025-02-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Phase Ia Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CUG252 in Normal Healthy Volunteers (2025-02-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate the Efficacy and Safety of Belimumab Administered in Combination With Rituximab to Adult Subjects With Systemic Lupus Erythematosus (SLE) - BLISS-BELIEVE (2025-02-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies (2025-02-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Telehealth CBT for Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus (2025-02-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Imvotamab in Severe Systemic Lupus Erythematosus (2025-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases (2025-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE) (2025-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Systemic Lupus Erythematosus Within the Framework of the Multidisciplinary Consultation (2025-02-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Ustekinumab in Chinese Participants With Active Systemic Lupus Erythematosus (2025-02-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Single Ascending Dose Study in Healthy Participants and Multiple Dose Study of JNJ-55920839 in Participants With Mild to Moderate Systemic Lupus Erythematosus (2025-02-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Establishing the Salience of Type 1 Interferon Pathway Blockade in the Central Mechanisms of SLE Related Fatigue (2025-01-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus (2025-01-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases (2025-01-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of CM313(SC) Injection in Systemic Lupus Erythematosus(SLE) (2025-01-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. CD19/BCMA CAR-T Cell Therapy for Refractory/Relapsed Lupus Nephritis (2025-01-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus (2025-01-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biomarkers in Inflammatory Rheumatic Diseases Diagnosis (2025-01-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State (2025-01-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (2025-01-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Long-term Follow-up for Evaluating the Safety of CS20AT04 in Subject with Lupus Nephritis (2025-01-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Clinical Study of CD19 Universal CAR-γδT Cells in Active Systemic Lupus Erythematosus (2025-01-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Clinical Study of CD19 CAR-T in Active Systemic Lupus Erythematosus (2025-01-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ELEVATE - (Empower Lupus Erythematosus Patients Via Allowing RemoTe Evaluation) (2025-01-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Vitamin D Supplement on Disease Activity in SLE (2025-01-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Renal Resistive Index as an Indicator of Lupus Nephritis Severity and Systemic Lupus Activity (2025-01-03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Major Systemic Lupus Erythematosus Exacerbation after Severe Clostridium Difficile Infection: A Case Report. (2024/12/31) ♡
• Brain perfusion and blood-brain barrier permeability in systemic lupus erythematosus patients: Associations with disease activity, cognitive dysfunction, fatigue and pain. (2024/12/31) ♡
• Role of serum procalcitonin in differentiating disease flare and systemic bacterial infection among febrile children with known chronic rheumatic diseases: a cross-sectional study. (2024/12/30) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Rare Case of Steroid-Induced Hypothermia in a Patient With Systemic Lupus Erythematosus. (2024/12/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Relapsed immune thrombotic thrombocytopenic purpura secondary to systemic lupus erythematosus: a case report and literature review]. (2024/12/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Hypoprothrombinemia-lupus anticoagulant syndrome: a case report and literature review]. (2024/12/30) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Evans syndrome as a presentation in systemic lupus erythematosus, coexisting with Hashimoto's thyroiditis and pernicious anemia: a case report. (2024/12/28) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Systemic Lupus Erythematosus (SLE) Induced by ASIA Syndrome After the Aesthetic Medicine Procedures-A Case Report. (2024/12/28) ♡
• The role of UV-induced cutaneous matrix metalloproteinases and mi-RNAs in the pathogenesis of lupus erythematosus. (2024/12/28) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Temporary Global Amnesia With Insular Infarction in a Young Female: A Case Report. (2024/12/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Cutaneous Manifestations of Systemic Lupus Erythematosus and Their Correlation With Cardiac Involvement. (2024/12/27) ♡
• The effects of coagulation factors on the risk of autoimmune diseases: A Mendelian randomization study. (2024/12/27) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. COVID-19 induced thrombotic thrombocytopenic purpura in a patient with systemic lupus erythematosus: A rare case report. (2024/12/27) ♡
• Prevalence and Clinical Assessment of Skin Lesions in Systemic Lupus Erythematosus. (2024/12/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current use and development of monoclonal antibodies for the treatment of systemic lupus erythematosus: a review. (2024/12/26) ♡
• Chronic Low-Level IFN-γ Expression Disrupts Mitochondrial Complex I Activity in Renal Macrophages: An Early Mechanistic Driver of Lupus Nephritis Pathogenesis. (2024/12/25) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Rituximab (monoclonal anti-CD20 antibody) induced posterior reversible encephalopathy syndrome (PRES): A case report and literature review. (2024/12/24) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Kikuchi-Fujimoto disease associated optic neuropathy in an adolescent. (2024/12/24) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Red flags to suspect inborn errors of immunity in patients with autoimmune diseases. (2024/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Role of Sodium-Glucose Co-Transporter-2 (SGLT-2) Inhibitors in Treating Lupus Nephritis: A Systematic Review. (2024/12/21) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Case of Severe Lupus and Refractory Anemia. (2024/12/21) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Qihuang Jianpi Zishen Granules improves thrombocytopenia in mice with systemic lupus erythematosus by suppressing platelet autophagy via the Ca(2+)/CaMKK2/AMPK/mTOR signaling pathway]. (2024/12/20) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome. (2024/12/20) ♡

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