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Systemic lupus erythematosus (SLE)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest quality evidence only (108)Meta-analysis (40)Treatment guideline (2)Systematic review (34)Randomized trial (21)Phase 3 study (11)Clinical trial (605)Systematic review (376)Early study (phase 1 or 2) (31)Case report (317)Laboratory or animal study (58)Commentary or editorial (40)Retracted publication (3) Only studies currently seeking participants (44)

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Publications and studies (2492)

• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Two novel frameshift variations in the ELF4 gene expand the mutational spectrum of DEX: case report and literature review. (2025/07/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Adult-onset Seizures as the First Manifestation of Anti-dsDNA Negative Systemic Lupus Erythematosus. (2025/07/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Kikuchi Disease Unveiling Systemic Lupus Erythematosus: A Rare Case of Initial Manifestation. (2025/07/31) ♡
• Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. Lang-chuang-ding restores bone homeostasis in systemic lupus erythematosus associated osteoporosis by targeting NF-κB signaling: a network pharmacology and experimental study. (2025/07/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Understanding Sex Differences in Autoimmune Diseases: Immunologic Mechanisms. (2025/07/23) ♡
• Bank1 deficiency reshapes the gut microbiota of lupus mice towards an anti-inflammatory composition. (2025/07/21) ♡
• Higher PM2.5 exposure increases the risk of incident systemic lupus erythematosus: a prospective cohort study in Taiwan. (2025/07/20) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Could Skin Autofluorescence Be a Useful Biomarker in Systemic Lupus Erythematosus? A Systematic Review. (2025/07/19) ♡
• EBV and Autoimmunity. (2025/07/04) ♡
• Protective Role of Dietary Short-Chain Fatty Acid Propionate against Autoimmune Responses and Pathology of Systemic Lupus Erythematosus in MRL-lpr Mice. (2025/07/02) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Diagnostic and prognostic value of quantitative cardiac magnetic resonance imaging biomarkers in systemic lupus erythematosus: a systematic review and meta-analysis. (2025/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nephrology's Next Frontier: Expanding the Reach of CAR T-Cell Therapy for Refractory Lupus Nephritis and Beyond. (2025/07/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Clinical Characteristics and Risk Factors for Lupus Nephritis in Tunisian Patients With Systemic Lupus Erythematosus. (2025/07/01) ♡
• The potential mechanism of Huangqin for treatment of systemic lupus erythematosus based on network pharmacology, molecular docking and molecular dynamics simulation. (2025/06/26) ♡
• Increased neutrophil senescence is associated with impaired immunosuppressive activity in systemic lupus erythematosus. (2025/06/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Effect of Inflammation and Infection on Lipids and Lipoproteins. (2025/06/18) ♡
• Methyl supplemented diet reduces liver pathology in lupus-prone MRL/lpr mice. (2025/06/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The role of probiotics in promoting systemic immune tolerance in systemic lupus erythematosus. (2025/06/17) ♡
• Omega-3 Fatty Acid Synergy with Glucocorticoid in Lupus Macrophages: Targeting Pathogenic Pathways to Reduce Steroid Dependence. (2025/06/17) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Hydroxychloroquine enhances efferocytosis and modulates inflammation via MerTK/Gas6 signaling in a pristane-induced lupus mouse model. (2025/06/16) ♡
• Jieduquyuziyin prescription suppresses the activation of the extrafollicular effector B cell by regulating integrin αV signaling in systemic lupus erythematosus. (2025/06/12) ♡
• Study protocol for a randomized controlled trial to pilot Restore Energy, Activity Can Help (REACH): an mHealth-enabled peer coaching intervention for fatigue in systemic lupus erythematosus. (2025/06/07) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Immune metabolic restoration in systemic lupus erythematosus: the impact of gut microbiota, probiotics, and nutritional synergy. (2025/06/04) ♡
• Soufeng Sanjie formula alleviates the progression of lupus and joint injury by regulating the ALKBH5-FoxO1-PFKFB3 axis in M-MDSCs. (2025/06/01) ♡
• Identifying potential biomarkers in the hippocampus of chronic fatigue syndrome rats treated with moxibustion at Zusanli (ST36): a proteomics study. (2025/06/01) ♡
• Association between excess body weight and disordered eating attitude among women living with systemic lupus erythematosus. (2025/06/01) ♡
• Microbial dysbiosis fuels STING-driven autoinflammation through cyclic dinucleotides. (2025/06/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Severe gastrointestinal manifestations in childhood-onset lupus: A single-center cohort and review of the literature. (2025/06/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. IMPACT OF VITAMIN D METABOLISM DISORDERS ON THE DEVELOPMENT OF AUTOIMMUNE KIDNEY DISEASES: A SYSTEMATIC REVIEW. (2025/06/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Traditional Chinese medicine for intractable and rare diseases: Research progress and future strategies. (2025/05/31) ♡
• Bromocriptine in Rheumatic Diseases: A Review. (2025/05/30) ♡
• A data-driven approach to discover and quantify systemic lupus erythematosus etiological heterogeneity from electronic health records. (2025/05/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular Insight into the Role of Vitamin D in Immune-Mediated Inflammatory Diseases. (2025/05/16) ♡
• Genetic Causal Relationship Between Systemic Lupus Erythematosus and Malignant Tumors of the Female Reproductive System: A GWAS Analysis in European Populations. (2025/05/15) ♡
• Visceral fat, cardiovascular risk factors and quality of life in lupus activity categorised via complement C3. (2025/05/14) ♡
• Tripterygium glycoside tablets and triptolide alleviate experimental autoimmune encephalomyelitis mice involving the PACAP/cAMP signaling pathway. (2025/05/12) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. The Effect of Probiotic Yogurt Containing Lactobacillus rhamnosus and Bifidobacterium bifidum on Disease Activity and Disability in Patients with Systemic Lupus Erythematosus: A Randomized Controlled Trial. (2025/05/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Traditional Chinese medicine for lupus nephritis: modulation of autoimmune pathogenesis. (2025/05/02) ♡
• Role of STING Deficiency in Amelioration of Mouse Models of Lupus and Atherosclerosis. (2025/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Clinical Progress in Mesenchymal Stem Cell Therapy: A Focus on Rheumatic Diseases. (2025/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Deciphering the Role of Innate Lymphoid Cells Group 3 in the Gut Microenvironment: A Narrative Review of Their Novel Contributions to Autoimmune Disease Pathogenesis. (2025/04/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sarcopenia in Rheumatic Diseases: A Hidden Issue of Concern. (2025/04/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Unlocking the Power of the Mediterranean Diet: Two in One-Dual Benefits for Rheumatic and Thyroid Autoimmune Diseases. (2025/04/19) ♡
• Study on the mechanism of Jieduquyuziyin prescription improving the condition of MRL/lpr mice by regulating T cell metabolic reprogramming through the AMPK/mTOR pathway. (2025/04/09) ♡
• The Jieduquyuziyin prescription alleviates systemic lupus erythematosus by modulating B cell metabolic reprogramming via the AMPK/PKM2 signaling pathway. (2025/04/09) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Co-Occurrence of Systemic Sclerosis, Lupus, and Celiac Disease in Multiple Autoimmune Syndrome: A Case Report. (2025/04/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Modern therapy of patients with lupus erythematosus must include appropriate management of their heightened rates of atherosclerotic cardiovascular events: a literature update. (2025/04/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Systemic Lupus Erythematosus Features in Elderly Patients: Case-Based Review. (2025/04/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Research progress of the influence of dietary and nutritional factors on systemic lupus erythematosus]. (2025/04/06) ♡
• Leveraging Lifestyle Medicine for Better Outcomes in Connective Tissue Diseases. (2025/04/03) ♡

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