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Fatty liver disease (MASH/NASH), advanced

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (129)Meta-analysis (42)Randomized Trial (40)Systematic review (32)Phase 3 Study (15)Clinical research (223)Overview article (431)Early study (phase 1 or 2) (12)Laboratory or animal research (274)Single Patient Description (18)Commentary or Editorial (50)Retracted Publication (4) Studies currently seeking participants only (40)

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Publications and studies (2550)

• Commentary or editorialiAn expert's opinion or commentary, not new research. Is the name 'NAFLD' too big to fail? Let's keep it for nutrition-associated fatty liver disease. (2021/04/01) ♡
• Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production. (2021/04/01) ♡
• The metabolic and liver-related outcomes of bariatric surgery in adult patients with insulin-treated type 2 diabetes and nonalcoholic fatty liver disease at high risk of liver fibrosis. (2021/04/01) ♡
• Severity of metabolic syndrome is greater among nonalcoholic adults with elevated ALT and advanced fibrosis. (2021/04/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Protective effects of Dendrobium candidum Wall ex Lindl. on high-fat diet-induced liver damage in mice. (2021/04/01) ♡
• Triglyceride and glucose index: a useful tool for non-alcoholic liver disease assessed by liver biopsy in patients with metabolic syndrome? (2021/04/01) ♡
• Low expression of AQP9 and its value in hepatocellular carcinoma. (2021/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Potential Role of Dexamphetamine in the Treatment of Non-Alcoholic Fatty Liver Disease: Hopes and Pitfalls. (2021/04/01) ♡
• Anti-Obesity Effects of Artemisia annua Extract in Zucker Fatty Rats and High-Fat Diet Sprague Dawley Rats through Upregulation of Uncoupling Protein 1. (2021/03/30) ♡
• Xiaochaihu decoction for nonalcoholic fatty liver disease: A protocol for a systematic review and meta-analysis. (2021/03/26) ♡
• Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA) -treated HepG2 cells. (2021/03/25) ♡
• Fibroblast growth factor 21 levels and liver inflammatory biomarkers in obese subjects after weight loss. (2021/03/18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Analysis of steatosis biomarkers and inflammatory profile after adding on PCSK9 inhibitor treatment in familial hypercholesterolemia subjects with nonalcoholic fatty liver disease: A single lipid center real-world experience. (2021/03/10) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Apolipoprotein A5 controls fructose-induced metabolic dysregulation in mice. (2021/03/10) ♡
• Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice. (2021/03/10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pentraxin 3 and the TyG Index as Two Novel Markers to Diagnose NAFLD in Children. (2021/03/08) ♡
• Liraglutide Alleviates Hepatic Steatosis and Liver Injury in T2MD Rats via a GLP-1R Dependent AMPK Pathway. (2021/03/04) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Evaluation of Drug Delivery Nanocarrier Development and Pharmacological Briefing for Metabolic-Associated Fatty Liver Disease (MAFLD): An Update. (2021/03/04) ♡
• Development and course of diabetes according to genetic factors and diabetes treatment among patients with nonalcoholic fatty liver disease. (2021/03/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Underestimation of portal pressures by wedge hepatic venous pressures in patients with non-alcoholic steatohepatitis related cirrhosis- Possibilities and implications. (2021/03/01) ♡
• Use of a convolutional neural network and quantitative ultrasound for diagnosis of fatty liver. (2021/03/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Impact of Silymarin in individuals with nonalcoholic fatty liver disease: A systematic review and meta-analysis. (2021/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. G protein-coupled receptors: Key molecules in metabolic-associated fatty liver disease development. (2021/03/01) ♡
• S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling. (2021/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Exercise in mice ameliorates high-fat diet-induced nonalcoholic fatty liver disease by lowering HMGCS2. (2021/03/01) ♡
• Qinghua Fang inhibits high-fat diet-induced non-alcoholic fatty liver disease by modulating gut microbiota. (2021/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Drugs for Non-Alcoholic Steatohepatitis (NASH): Quest for the Holy Grail. (2021/02/28) ♡
• Lipid Profile Response to Electroacupuncture in Non-Alcoholic Fatty Liver Patients with Hyperlipidemia. (2021/02/28) ♡
• Comparison of hepatic gene expression profiles between three mouse models of Nonalcoholic Fatty Liver Disease. (2021/02/27) ♡
• TGR5 regulates Macrophage Inflammation in Nonalcoholic Steatohepatitis by Modulating NLRP3 Inflammasome Activation. (2021/02/22) ♡
• Insulin Fused to Apolipoprotein A-I Reduces Body Weight and Steatosis in DB/DB Mice. (2021/02/19) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Comparison of the Efficacy of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Metabolic Associated Fatty Liver Disease: Updated Systematic Review and Meta-Analysis. (2021/02/16) ♡
• Measuring acetyl-CoA and acetylated histone turnover in vivo: Effect of a high fat diet. (2021/02/15) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. The effects of glucagon-like peptide-1 receptor agonists on glycemic control and anthropometric profiles among diabetic patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. (2021/02/15) ♡
• Exposure to nitenpyram during pregnancy causes colonic mucosal damage and non-alcoholic steatohepatitis in mouse offspring: The role of gut microbiota. (2021/02/15) ♡
• Transcriptome analysis reveals the efficacy of ginsenoside-RG1 in the treatment of nonalcoholic fatty liver disease. (2021/02/15) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Gallic Acid Ameliorated Impaired Lipid Homeostasis in a Mouse Model of High-Fat Diet-and Streptozotocin-Induced NAFLD and Diabetes through Improvement of β-oxidation and Ketogenesis. (2021/02/12) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Sodium-Glucose Co-Transporter 2 Inhibitors for Non-Alcoholic Fatty Liver Disease in Asian Patients With Type 2 Diabetes: A Meta-Analysis. (2021/02/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Controversies and Opportunities in the Use of Inflammatory Markers for Diagnosis or Risk Prediction in Fatty Liver Disease. (2021/02/09) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Association of non-alcoholic fatty liver disease and all-cause mortality in hospitalized cardiovascular disease patients: A systematic review and meta-analysis. (2021/02/05) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Liver Injury Increases the Incidence of HCC following AAV Gene Therapy in Mice. (2021/02/03) ♡
• Integrated Analysis of Key Genes and Pathways Involved in Nonalcoholic Steatohepatitis Improvement After Roux-en-Y Gastric Bypass Surgery. (2021/02/02) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Extracellular Vesicles as Inflammatory Drivers in NAFLD. (2021/02/02) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Beneficial and deleterious effects of sitagliptin on a methionine/choline-deficient diet-induced steatohepatitis in rats. (2021/02/01) ♡
• β-patchoulene improves lipid metabolism to alleviate non-alcoholic fatty liver disease via activating AMPK signaling pathway. (2021/02/01) ♡
• Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases. (2021/02/01) ♡
• Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses. (2021/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. ER stress-induced adipocytes secrete-aldo-keto reductase 1B7-containing exosomes that cause nonalcoholic steatohepatitis in mice. (2021/02/01) ♡
• The association between dietary antioxidant index (DAI) and nonalcoholic fatty liver disease (NAFLD) onset; new findings from an incident case-control study. (2021/02/01) ♡
• Dietary polyphenols and the odds of non-alcoholic fatty liver disease: A case-control study. (2021/02/01) ♡

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