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Fatty liver disease (MASH/NASH), advanced

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (129)Meta-analysis (42)Randomized Trial (40)Systematic review (32)Phase 3 Study (15)Clinical research (223)Overview article (431)Early study (phase 1 or 2) (12)Laboratory or animal research (274)Single Patient Description (18)Commentary or Editorial (50)Retracted Publication (4) Studies currently seeking participants only (40)

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Publications and studies (2550)

• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Receptor-interacting protein 1 and 3 kinase activity are required for high-fat diet induced liver injury in mice. (2023/12/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exploring a novel therapeutic strategy: the interplay between gut microbiota and high-fat diet in the pathogenesis of metabolic disorders. (2023/12/15) ♡
• Fibroblast Growth Factor 21: A More Effective Biomarker Than Free Fatty Acids and Other Insulin Sensitivity Measures for Predicting Non-alcoholic Fatty Liver Disease in Saudi Arabian Type 2 Diabetes Patients. (2023/12/14) ♡
• Decreased FXR Agonism in the Bile Acid Pool Is Associated with Impaired FXR Signaling in a Pig Model of Pediatric NAFLD. (2023/12/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Research progress of traditional Chinese medicine in improving hepatic fibrosis based on inhibiting pathological angiogenesis. (2023/12/12) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Impact of multiple different high-fat diets on metabolism, inflammatory markers, dysbiosis, and liver histology: study on NASH rat model induced diet. (2023/12/12) ♡
• Association between body roundness index and risk of ultrasound-defined non-alcoholic fatty liver disease. (2023/12/10) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Thyroid Hormone and Mitochondrial Dysfunction: Therapeutic Implications for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). (2023/12/09) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular Mechanisms of Curcumin in the Pathogenesis of Metabolic Dysfunction Associated Steatotic Liver Disease. (2023/12/09) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Vagal Stimulation Ameliorates Non-Alcoholic Fatty Liver Disease in Rats. (2023/12/08) ♡
• Differential Interventional Effects of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on High Fat Diet-Induced Obesity and Hepatic Pathology. (2023/12/08) ♡
• Cholesterol Exacerbates the Pathophysiology of Non-Alcoholic Steatohepatitis by Upregulating Hypoxia-Inducible Factor 1 and Modulating Microcirculatory Dysfunction. (2023/12/08) ♡
• Effects of Fish Oil Supplementation on Reducing the Effects of Paternal Obesity and Preventing Fatty Liver in Offspring. (2023/12/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A Comprehensive Review on Non-Alcoholic Fatty Liver Disease. (2023/12/08) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. The Ameliorating Effects of n-3 Polyunsaturated Fatty Acids on Liver Steatosis Induced by a High-Fat Methionine Choline Deficient Diet in Mice. (2023/12/07) ♡
• The association of systemic inflammatory biomarkers with non-alcoholic fatty liver disease: a large population-based cross-sectional study. (2023/12/07) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The pleiotropic approach to coronavirus disease-19 pathogenesis: The impact of liver diseases associated host genetic variants. (2023/12/07) ♡
• Oral Insulin Alleviates Liver Fibrosis and Reduces Liver Steatosis in Patients With Metabolic Dysfunction-associated Steatohepatitis and Type 2 Diabetes: Results of Phase II Randomized, Placebo-controlled Feasibility Clinical Trial. (2023/12/07) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Genetic and epigenetic determinants of non-alcoholic fatty liver disease (NAFLD) in lean individuals: a systematic review. (2023/12/06) ♡
• Does myo-inositol supplementation influence oxidative stress biomarkers in patients with non-alcoholic fatty liver disease? (2023/12/06) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Digeda-4 decoction and its disassembled prescriptions improve dyslipidemia and apoptosis by regulating AMPK/SIRT1 pathway on tyloxapol-induced nonalcoholic fatty liver disease in mice. (2023/12/05) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Tiaogan Jiejiu Tongluo Formula attenuated alcohol-induced chronic liver injury by regulating lipid metabolism in rats. (2023/12/05) ♡
• The Multicomponent Medicinal Product Hepar Compositum Reduces Hepatic Inflammation and Fibrosis in a Streptozotocin- and High-Fat Diet-Induced Model of Metabolic Dysfunction-Associated Steatotic Liver Disease/Metabolic Dysfunction-Associated Steatohepatitis. (2023/12/04) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. NAFLD and type 2 diabetes: A practical guide for joint management. (2023/12/01) ♡
• Jianpi-qinghua formula attenuates nonalcoholic fatty liver disease by regulating the AMPK/SIRT1/NF-βB pathway in high-fat-diet-fed C57BL/6 mice. (2023/12/01) ♡
• Optimization of the proportions of advantageous components in the hypolipidemic “bioequivalent substance system” of Jiang-Zhi-Ning and its mechanism of action. (2023/12/01) ♡
• Active ingredients of Erhuang Quzhi Granules for treating non-alcoholic fatty liver disease based on the NF-κb/NLRP3 pathway. (2023/12/01) ♡
• A classical herbal formula alleviates high-fat diet induced nonalcoholic steatohepatitis (NASH) via targeting mitophagy to rehabilitate dysfunctional mitochondria, validated by UPLC-HRMS identification combined with in vivo experiment. (2023/12/01) ♡
• Periodontal Disease and Metabolic Syndrome: Statistical and Machine Learning Analytics of a Nationwide Study. (2023/12/01) ♡
• Outcomes of SGLT-2i and GLP-1RA Therapy Among Patients With Type 2 Diabetes and Varying NAFLD Status. (2023/12/01) ♡
• Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy. (2023/12/01) ♡
• [Lipid-lowering effect of drug pair Scutellariae Radix-Coptidis Rhizoma based on lipomics]. (2023/12/01) ♡
• Rosae multiflorae fructus regulates lipogenesis in high-fat diet-induced NAFLD mice model. (2023/12/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A sport supplement candidate of Erigeron breviscapus extract regulates lipogenesis in vitro and in vivo. (2023/12/01) ♡
• COMPARATIVE ANALYSIS OF THE EFFECTS OF SOME HEPATOPROTECTORS IN EXPERIMENTALLY INDUCED MAFLD IN ADULT WISTAR RATS. (2023/12/01) ♡
• High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease. (2023/12/01) ♡
• Effect of vitamin D supplementation on various parameters in patients with non-alcoholic fatty liver disease: An updated meta-analysis. (2023/12/01) ♡
• Risk of dementia in the elderly with non-alcoholic fatty liver disease: A nested case-control study in the Republic of Korea. (2023/11/29) ♡
• The Association of Perfluoroalkyl Substance Exposure and a Serum Liver Function Marker in Korean Adults. (2023/11/28) ♡
• AKR1B1 drives hyperglycemia-induced metabolic reprogramming in MASLD-associated hepatocellular carcinoma. (2023/11/28) ♡
• The Hepatic Antisteatosis Effect of Xanthohumol in High-Fat Diet-Fed Rats Entails Activation of AMPK as a Possible Protective Mechanism. (2023/11/22) ♡
• [Metabolic study of iron deposition based on magnetic resonance in patients with nonalcoholic fatty liver disease]. (2023/11/20) ♡
• [Research progress on AMPK activation in nonalcoholic fatty liver disease]. (2023/11/20) ♡
• Ultra-processed food consumption and non-alcoholic fatty liver disease, metabolic syndrome and insulin resistance: A systematic review. (2023/11/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Efferocytosis in liver disease. (2023/11/16) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Study on the mechanism of Shuganzhi Tablet against nonalcoholic fatty liver disease and lipid regulation effects of its main substances in vitro. (2023/11/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Reactive oxygen species (ROS) -mediated oxidative stress in chronic liver diseases and its mitigation by medicinal plants. (2023/11/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Myosteatosis: Diagnosis, pathophysiology and consequences in metabolic dysfunction-associated steatotic liver disease. (2023/11/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Serum biomarkers for liver fibrosis assessment. (2023/11/14) ♡
• Chitobiose exhibited a lipid-lowering effect in ob/ob (-/-) mice via butyric acid enrolled liver-gut crosstalk. (2023/11/09) ♡

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