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Fatty liver disease (MASH/NASH), advanced

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (129)Meta-analysis (42)Randomized Trial (40)Systematic review (32)Phase 3 Study (15)Clinical trial (222)Review article (430)Early study (phase 1 or 2) (12)Laboratory or Animal Study (273)Single Patient Description (18)Commentary or Editorial (50)Retracted Publication (4) Studies currently seeking participants only (40)

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Publications and studies (2544)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult Participants (2026-01-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ENDOCARE-SCREEN: Metabolic Liver Dysfunction Screening Study (2026-01-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA (2026-01-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Detection of Helicopacter Pylori in Patients With Metabolic Associated Fatty Liver Disease (2026-01-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety, Tolerability, PK, PD, and Immunogenicity of QL2401 in Healthy Chinese Adults (2026-01-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Long Term Prediction of MASH-related HCC Risk by Proteomics (2026-01-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo) (2026-01-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Betaine vs. Placebo for Serologically Diagnosed Metabolic Dysfunction-associated Steatohepatitis (MASH) (2026-01-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Thermoacoustic Method for Estimating Liver Fat Fraction (2026-01-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Indianized Version of Mediterranean Diet vs. Low Fat Diet on Hepatic Steatosis in Overweight Children and Adolescent With MASLD (2026-01-06) ♡
• Betaine Attenuates High-Fat-Diet-Induced Metabolism-Associated Steatotic Liver Disease via the Inhibition of Ferroptosis Through the Nrf2/GPX4 Axis. (2025/12/31) ♡
• Revealing the Causal Relationship of the Gut-Liver Axis in MASH: A Study Based on Mendelian Randomization and Multi-Omics. (2025/12/31) ♡
• MASLD or MetALD? Unveiling the Role of Alcohol in Liver Disease Progression in Diabetic Patients. (2025/12/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Metabolic Dysfunction-Associated Steatotic Liver Disease-CKD Axis: Intersecting Pathways and Opportunities for Early Intervention. (2025/12/30) ♡
• Preparation of sea cucumber collagen hydrolysate and its inhibitory effect on α-glucosidases. (2025/12/30) ♡
• Diet-induced steatohepatitis does not cause heart failure with preserved ejection fraction in male middle-aged C57BL/6N mice. (2025/12/29) ♡
• Ultrasound and SWE-based transfer learning for predicting fibrotic NASH. (2025/12/29) ♡
• The Therapeutic Effect and Mechanism of Lactobacillus gardneri on Nonalcoholic Fatty Liver Disease. (2025/12/29) ♡
• Low Rates of MASLD Screening in Young Adults With Type 2 Diabetes: A Retrospective Cohort Study. (2025/12/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Quality and Quantity? The Clinical Significance of Myosteatosis in Various Liver Diseases: A Narrative Review. (2025/12/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Lipidomic Signatures in Pediatric Metabolic Disorders. (2025/12/28) ♡
• [Comparison of 16S rRNA gene hypervariable regions V3-V4 and V4 sequencing results of gut microbiota in obese children with non-alcoholic fatty liver disease]. (2025/12/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Histone lactylation: A key epigenetic modulator in the pathogenesis of metabolic dysfunction-associated steatohepatitis and alcoholic steatohepatitis. (2025/12/27) ♡
• Transcriptome profiles of peripheral blood mononuclear cells differentiate male adolescents with non-alcoholic fatty liver disease from healthy peers. (2025/12/27) ♡
• Increased intestinal Lactobacillus abundance in post-pancreatectomy steatotic liver disease is associated with altered bile acid metabolism and FXR-FGF19 pathway suppression. (2025/12/27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Diagnostic Performance of LIVERFASt as a Non-invasive Liver Fibrosis Test: Data from Three Cohorts of Patients with Metabolic Dysfunction-associated Steatotic Liver Disease. (2025/12/26) ♡
• Life's essential 8 and non-alcoholic fatty liver disease: unmasking depressive symptoms' mediating role. (2025/12/26) ♡
• Exploring the potential mechanisms of OSBPL3 in metabolic dysfunction-associated steatotic liver disease by integrating bulk and single-cell RNA sequencing data. (2025/12/26) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Doubling the diagnostic rate of at-risk metabolic dysfunction-associated steatohepatitis-leave no one behind: author's reply. (2025/12/26) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Protective role of hydroalcoholic extract of Medusomyces gisevii L. in non-alcoholic fatty liver disease: insights from a murine model. (2025/12/26) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Phenotypic Screening Coupled with AI-Driven Target Deconvolution Identifies α-Terthienyl as a Dual DPP-IV/HSD17β13 Modulator with Efficacy in a Mouse Model of MASLD. (2025/12/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metabolic dysfunction and alcohol-associated liver disease (MetALD). (2025/12/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mini-Review: The Detoxification Effects of Black Radish in Metabolically Dysfunctional-Associated Fatty Liver Disease. (2025/12/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Health Risks Associated with a Long-Term Gluten-Free Diet and the Potential Protective Role of Anthocyanins. (2025/12/25) ♡
• Assessing and Addressing Medical Residents' Knowledge Gaps in the Screening and Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, and Metabolic Syndrome: A Quality Improvement Project. (2025/12/25) ♡
• Trends in Prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Nationwide Survey in Korea. (2025/12/24) ♡
• A Comparative Evaluation of the Effects of Saroglitazar and Pioglitazone on Hepatic and Metabolic Parameters in Type 2 Diabetes Mellitus With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). (2025/12/24) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Mapping research landscapes: a bibliometric and visual analysis of ketogenic diet interventions in liver health (2013-2024). (2025/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Role of Mitochondrial Dynamics in Metabolic Dysfunction-Associated Steatotic Liver Disease and the Regulatory Mechanisms of Exercise Intervention: A Systematic Review of Preclinical Studies. (2025/12/23) ♡
• Mycobiome dysbiosis and genetic predisposition to elevated IL-17A contribute to fibrosis in MASLD. (2025/12/23) ♡
• The KLB rs12152703 variant confers protection against hepatic inflammation in patients with MASLD by boosting Klotho-beta expression. (2025/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathogenesis of Type 2 Diabetes Mellitus. (2025/12/22) ♡
• Association between obesity and non-alcoholic fatty liver disease (NAFLD) in adults aged 18 years and above - data from NHANES 2017-2018. (2025/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathophysiology of depression and anxiety in metabolic dysfunction-associated steatotic liver disease. (2025/12/22) ♡
• Metabolic changes after hepatectomy: Implications for perioperative management and long-term outcomes. (2025/12/22) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Agrimonia pilosa Extract Alleviates CDAHFD-Induced Non-Alcoholic Steatohepatitis and Fibrosis in Mice. (2025/12/22) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Comparative Evaluation of the Effects of Oral Anti-hyperglycemic Agents and an Ayurvedic Hepatoprotective Agent in a Rat Model of Non-alcoholic Fatty Liver Disease (NAFLD). (2025/12/22) ♡
• Antioxidant Clove Extract Inhibits Lipid Droplet Accumulation and Lipid Oxidation in Hepatocytes. (2025/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Emerging Challenge of Non-Cirrhotic MASLD-Related Hepatocellular Carcinoma: Etiology, Immunopathology, and Precision Oncology. (2025/12/22) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Hugan Decoction alleviates non-alcoholic fatty liver disease in rats by activating the AMPK/m-TOR signaling pathway and reducing lipid synthesis]. (2025/12/20) ♡

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