Frontotemporal dementia
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Publications and studies (1588)
- Clinical and MRI Predictors of Conversion From Mild Behavioural Impairment to Dementia. (2020/07/01) ♡
- Classification using fractional anisotropy predicts conversion in genetic frontotemporal dementia, a proof of concept. (2020/06/11) ♡
- Using music interventions in the care of people with dementia. (2020/06/03) ♡
- Structural dissection of amyloid aggregates of TDP-43 and its C-terminal fragments TDP-35 and TDP-16. (2020/06/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. An elderly patient with Alzheimer's disease, normal pressure hydrocephalus and traumatic brain injury: presented with behavioural symptoms similar to behavioural variant frontotemporal dementia? (2020/06/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Generation, Analyzing and in-vivo Drug Treatment of Drosophila Models with IBMPFD. (2020/05/20) ♡
- Plasma cholesterol in Alzheimer's disease and frontotemporal dementia. (2020/05/18) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A case of limbic encephalitis evolving into a frontotemporal dementia-like picture. (2020/05/01) ♡
- Patterns of olfactory functional networks in Parkinson's disease dementia and Alzheimer's dementia. (2020/05/01) ♡
- High-throughput Flow Cytometry Assay to Investigate TDP43 Splicing Function. (2020/04/20) ♡
- Serial position effects rapidly distinguish Alzheimer's from frontotemporal dementia. (2020/04/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. An update on fluid biomarkers for neurodegenerative diseases: recent success and challenges ahead. (2020/04/01) ♡
- Disease-specific profiles of apathy in Alzheimer's disease and behavioural-variant frontotemporal dementia differ across the disease course. (2020/04/01) ♡
- Trajectory of lobar atrophy in asymptomatic and symptomatic GRN mutation carriers: a longitudinal MRI study. (2020/04/01) ♡
- Diffusion tensor imaging evidence of corticospinal pathway involvement in frontotemporal lobar degeneration. (2020/04/01) ♡
- Is there a glucose metabolic signature of spreading TDP-43 pathology in amyotrophic lateral sclerosis? (2020/03/01) ♡
- TMS for staging and predicting functional decline in frontotemporal dementia. (2020/03/01) ♡
- Role for ATXN1, ATXN2, and HTT intermediate repeats in frontotemporal dementia and Alzheimer's disease. (2020/03/01) ♡
- Longitudinal transcriptomic analysis of altered pathways in a CHMP2B(intron5)-based model of ALS-FTD. (2020/03/01) ♡
- Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy. (2020/03/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluating the reliability of neurocognitive biomarkers of neurodegenerative diseases across countries: A machine learning approach. (2020/03/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Two pathologically confirmed cases of novel mutations in the MAPT gene causing frontotemporal dementia. (2020/03/01) ♡
- Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND. (2020/03/01) ♡
- Normal brain aging and Alzheimer's disease are associated with lower cerebral pH: an in vivo histidine (1)H-MR spectroscopy study. (2020/03/01) ♡
- Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death. (2020/03/01) ♡
- Neuroendocrine Disturbances in Neurodegenerative Disorders: A Scoping Review. (2020/03/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model. (2020/02/19) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging small-molecule therapeutic approaches for amyotrophic lateral sclerosis and frontotemporal dementia. (2020/02/15) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. (2020/02/07) ♡
- Modulating ALS-Related Amyloidogenic TDP-43(307-319) Oligomeric Aggregates with Computationally Derived Therapeutic Molecules. (2020/02/04) ♡
- Scene construction impairments in frontotemporal dementia: Evidence for a primary hippocampal contribution. (2020/02/03) ♡
- Differences in neuroimaging features of early- versus late-onset nonfluent/agrammatic primary progressive aphasia. (2020/02/01) ♡
- Anti-GluA3 antibodies in frontotemporal dementia: effects on glutamatergic neurotransmission and synaptic failure. (2020/02/01) ♡
- Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study. (2020/02/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. International view on genetic frontotemporal dementia. (2020/02/01) ♡
- Brain metabolic signatures across the Alzheimer's disease spectrum. (2020/02/01) ♡
- Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity. (2020/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. New Roles for Canonical Transcription Factors in Repeat Expansion Diseases. (2020/02/01) ♡
- CSF angiogenin levels in amyotrophic lateral sclerosis-Frontotemporal dementia spectrum. (2020/02/01) ♡
- Self-assembly hollow manganese Prussian white nanocapsules attenuate Tau-related neuropathology and cognitive decline. (2020/02/01) ♡
- Behavioral manifestations in a Brazilian non-demented C9orf72-negative ALS population. (2020/02/01) ♡
- Motor function decline correlates with behavioral impairment in C9orf72 mutation carriers. (2020/01/21) ♡
- Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules. (2020/01/17) ♡
- REM sleep atonia loss distinguishes synucleinopathy in older adults with cognitive impairment. (2020/01/07) ♡
- Three-Dimensional Structure of RNA Monomeric G-Quadruplex Containing ALS and FTD Related G4C2 Repeat and Its Binding with TMPyP4 Probed by Homology Modeling based on Experimental Constraints and Molecular Dynamics Simulations. (2020/01/02) ♡
- Acquired Hemicerebral Atrophy Secondary to Chronic Internal Carotid Steno-Occlusive Disease: A Case Series. (2020/01/01) ♡
- Verbal Semantics and the Left Dorsolateral Anterior Temporal Lobe: A Longitudinal Case of Bilateral Temporal Degeneration. (2020/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Knock-in of Mutated hTAU Causes Insulin Resistance, Inflammation and Proteostasis Disturbance in a Mouse Model of Frontotemporal Dementia. (2020/01/01) ♡
- Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia. (2020/01/01) ♡
- Omega-3 Fatty Acids Increase Amyloid-β Immunity, Energy, and Circadian Rhythm for Cognitive Protection of Alzheimer's Disease Patients Beyond Cholinesterase Inhibitors. (2020/01/01) ♡
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