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Frontotemporal dementia

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the strongest evidence (41)Meta-analysis (10)Treatment guideline (3)Systematic review (21)Phase 3 study (5)Randomized trial (2)Clinical trial (463)Review article (188)Early study (phase 1 or 2) (16)Case report (73)Laboratory or animal research (38)Commentary or editorial (26) Studies currently recruiting participants only (35)

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Publications and studies (1588)

• Discussing personalized prognosis in amyotrophic lateral sclerosis: development of a communication guide. (2020/12/14) ♡
• Progranulin Adsorbs to Polypropylene Tubes and Disrupts Functional Assays: Implications for Research, Biomarker Studies, and Therapeutics. (2020/12/14) ♡
• Young-onset frontotemporal dementia with FUS pathology. (2020/12/11) ♡
• TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS. (2020/12/10) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Rare case of Marchiafava-Bignami disease due to thiamine deficiency and malnutrition. (2020/12/10) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Cytoplasmic Expression of the ALS/FTD-Related Protein TDP-43 Decreases Global Translation Both in vitro and in vivo. (2020/12/08) ♡
• Repeatability of Commonly Used Speech and Language Features for Clinical Applications. (2020/12/02) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia. (2020/12/01) ♡
• Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation. (2020/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Frontal Variant of Alzheimer Disease Differentiated From Frontotemporal Dementia Using in Vivo Amyloid and Tau Imaging. (2020/12/01) ♡
• Validation of the Dépistage Cognitif de Québec in the Oldest Old. (2020/12/01) ♡
• Moral reasoning and moral conflict in patients of the amyotrophic lateral sclerosis - Frontotemporal dementia spectrum. (2020/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Cerebral toxoplasmosis and alcohol abuse in AIDS: dementia with multiple etiologies. (2020/12/01) ♡
• SQSTM1(L341V) variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells. (2020/11/30) ♡
• Sporadic Creutzfeldt-Jakob Disease and Other Proteinopathies in Comorbidity. (2020/11/30) ♡
• Dietary Habits and Risk of Early-Onset Dementia in an Italian Case-Control Study. (2020/11/29) ♡
• Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases. (2020/11/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Antisense Transcription across Nucleotide Repeat Expansions in Neurodegenerative and Neuromuscular Diseases: Progress and Mysteries. (2020/11/27) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Editorial: Proteomics as a Tool for Biomarker and Drug Target Discovery: Improving the Diagnosis and Treatment of Neurodegenerative Diseases. (2020/11/26) ♡
• Frontal and Cerebellar Atrophy Supports FTSD-ALS Clinical Continuum. (2020/11/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies. (2020/11/25) ♡
• Resting State Functional Connectivity Is Decreased Globally Across the C9orf72 Mutation Spectrum. (2020/11/19) ♡
• The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment. (2020/11/17) ♡
• Cerebellar contributions to cognition in corticobasal syndrome and progressive supranuclear palsy. (2020/11/16) ♡
• Fronto-temporal dementia risk gene TMEM106B has opposing effects in different lysosomal storage disorders. (2020/11/16) ♡
• Longitudinal Characterization of Transcriptomic, Functional, and Morphological Features in Human iPSC-Derived Neurons and Their Application to Investigate Translational Progranulin Disease Biology. (2020/11/12) ♡
• Impact of Confinement on the Burden of Caregivers of Patients with the Behavioral Variant of Frontotemporal Dementia and Alzheimer Disease during the COVID-19 Crisis in France. (2020/11/12) ♡
• Comparative Study of the Word Capacity and Episodic Memory of Patients with Degenerative Dementia. (2020/11/08) ♡
• Comparison of Common and Disease-Specific Post-translational Modifications of Pathological Tau Associated With a Wide Range of Tauopathies. (2020/11/04) ♡
• Social Cognition Deficits Are Pervasive across Both Classical and Overlap Frontotemporal Dementia Syndromes. (2020/11/04) ♡
• Japanese Familial Cases of Frontotemporal Dementia and Parkinsonism with N279K Tau Gene Mutation. (2020/11/03) ♡
• Tau protein phosphorylation at Thr(175) initiates fibril formation via accessibility of the N-terminal phosphatase-activating domain. (2020/11/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Nutritional supplements for neuropsychiatric symptoms in people with dementia: A systematic review and meta-analysis. (2020/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neuropathology of primary lateral sclerosis. (2020/11/01) ♡
• Molecular Imaging Biomarkers in Dementia: Amyloid and tau PET imaging aids evaluation of patients suspected of having Alzheimer disease or other dementias. (2020/11/01) ♡
• Environmental Risk Factors for Early-Onset Alzheimer's Dementia and Frontotemporal Dementia: A Case-Control Study in Northern Italy. (2020/10/29) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. C9ORF72 hexanucleotide repeat expansion with Alzheimer's disease-like clinical phenotype: A case report with results from neuropsychology, CSF, FDG-PET, and PiB-PET. (2020/10/27) ♡
• Hybrid imaging in dementia: A semi-quantitative ((18)F)-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging approach in clinical practice. (2020/10/02) ♡
• Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress. (2020/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic lateral sclerosis: a clinical review. (2020/10/01) ♡
• The Relationship Between Dementia Subtypes and Nutritional Parameters in Older Adults. (2020/10/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Globular glial tauopathy Type I presenting with behavioral variant frontotemporal dementia. (2020/10/01) ♡
• Time reference, morphology and prototypicality: tense production in stroke aphasia and semantic dementia in Greek. (2020/09/01) ♡
• C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. (2020/09/01) ♡
• Role of zinc transporter ZIP12 in susceptibility-weighted brain magnetic resonance imaging (MRI) phenotypes and mitochondrial function. (2020/09/01) ♡
• Neuromodulation of Glial Function During Neurodegeneration. (2020/08/21) ♡
• Nutritional status and structural brain changes in Alzheimer's disease: The NUDAD project. (2020/08/11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Behavioural Disturbances in Patients with Diagnosis of Neurocognitive Disorder in Bogotá (Colombia). (2020/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Frontotemporal dementia: an unusual cause. (2020/07/01) ♡
• Binding of [(18)F]AV1451 in post mortem brain slices of semantic variant primary progressive aphasia patients. (2020/07/01) ♡

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