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Frontotemporal dementia
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Publications and studies (1588)
- Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia. (2024/05/01) ♡
- A guide to selecting high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence. (2024/04/08) ♡
- A mother and her daughter carrying a pathogenic expansion of the HTT gene with a phenotype encompassing motor neuron disease and Huntington's disease. (2024/04/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy. (2024/03/25) ♡
- Tracing TMEM106B fibril deposition in aging and Parkinson's disease with dementia brains. (2024/03/07) ♡
- Analysis of C9orf72 repeat expansions in Georgian patients with Amyotrophic lateral sclerosis (ALS). (2024/03/06) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Impact of voluntary exercise training on the metabolic and behavioral characteristics of the rTg4510 transgenic mouse model of frontotemporal dementia. (2024/03/05) ♡
- Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity. (2024/03/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A case of folate deficiency showing behavioural variant of frontotemporal dementia-like symptoms. (2024/03/01) ♡
- The relationship between social cognitive processes and behavior changes in people with amnestic mild cognitive impairment or dementia using the Edinburgh Social Cognition Test (ESCoT). (2024/03/01) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase 1 Study of Cabozantinib and Trifluridine/Tipiracil in Metastatic Colorectal Adenocarcinoma. (2024/03/01) ♡
- Association of plasma biomarkers with cognition, cognitive decline, and daily function across and within neurodegenerative diseases: Results from the Ontario Neurodegenerative Disease Research Initiative. (2024/03/01) ♡
- Pathology-specific patterns of cerebellar atrophy in neurodegenerative disorders. (2024/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A three-dimensional model of neural activity and phenomenal-behavioral patterns. (2024/03/01) ♡
- Establishment of a high-content imaging assay for tau aggregation in hiPSC-derived neurons differentiated from two protocols to routinely evaluate compounds and genetic perturbations. (2024/03/01) ♡
- A comparative transcranial magnetic stimulation study: Assessing cortical excitability and plasticity in Alzheimer's disease, dementia with Lewy bodies and Frontotemporal dementia. (2024/03/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Utility of the Japanese version of the Clinical Dementia Rating® plus National Alzheimer's Coordinating Centre Behaviour and Language Domains for sporadic cases of frontotemporal dementia in Japan. (2024/03/01) ♡
- Examining the relation between bilingualism and age of symptom onset in frontotemporal dementia. (2024/03/01) ♡
- Simultaneous determination of tipiracil, trifluridine and its metabolite 5-trifluoromethyluracil in human plasma using segmented polarity LC-MS/MS: A fully validated assay with clinical application. (2024/02/15) ♡
- A 3'UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated With Increased Risk for FTLD-TDP. (2024/02/05) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Behavioral Variant Frontotemporal Dementia With the Dominantly Affected Caudate Nucleus in 18 F-FP-CIT PET/CT. (2024/02/01) ♡
- Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. (2024/02/01) ♡
- Neurite-based white matter alterations in MAPT mutation carriers: A multi-shell diffusion MRI study in the ALLFTD consortium. (2024/02/01) ♡
- The effect of aperiodic components in distinguishing Alzheimer's disease from frontotemporal dementia. (2024/02/01) ♡
- Cerebrospinal fluid level of proNGF as potential diagnostic biomarker in patients with frontotemporal dementia. (2024/01/25) ♡
- Changes in Digital Speech Measures in Asymptomatic Carriers of Pathogenic Variants Associated With Frontotemporal Degeneration. (2024/01/23) ♡
- Influence of care modes and social resources on psychotropic medication use in community-dwelling dementia patients. (2024/01/16) ♡
- An examination of criminal offenders with dementia in Australian courts. (2024/01/16) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Editorial: Molecular mechanisms underlying C9orf72 neurodegeneration, volume II. (2024/01/08) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Lithium management of periodic mood fluctuations in behavioural frontotemporal dementia: a case report. (2024/01/08) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging perspectives of synaptic biomarkers in ALS and FTD. (2024/01/05) ♡
- Apathy-like behaviour in tau mouse models of Alzheimer's disease and frontotemporal dementia. (2024/01/05) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Editorial: The role of glial cells in neurodegeneration. (2024/01/04) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Targeted examination of amyloid beta and tau protein accumulation via positron emission tomography for the differential diagnosis of Alzheimer's disease based on the A/T(N) research framework. (2024/01/01) ♡
- TAF15 amyloid filaments in frontotemporal lobar degeneration. (2024/01/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Psychological and social impacts of frontotemporal dementia on caregivers and family members - A systematic review. (2024/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Tau and neurodegeneration. (2024/01/01) ♡
- Population-Based Characterization of the Pharmacokinetics and Food Effect of ANAVEX3-71, a Novel Sigma-1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer Disease. (2024/01/01) ♡
- Fatal Complication of Mouthguard Used to Treat Awake Bruxism in Patient with Frontotemporal Dementia. (2024/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The autophagy of stress granules. (2024/01/01) ♡
- Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia. (2024/01/01) ♡
- Assessing network degeneration and phenotypic heterogeneity in genetic frontotemporal lobar degeneration by decoding FDG-PET. (2024/01/01) ♡
- Remote respiratory resistance exercise training improves respiratory function in individuals with VCP multisystem proteinopathy. (2024/01/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Adolescent-onset multisystem proteinopathy due to a novel VCP variant. (2024/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD. (2024/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Overview of late-onset psychoses. (2024/01/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Clinical Phenotype of Behavioral-Variant Frontotemporal Dementia Reversed by ECT: A Case Report. (2024/01/01) ♡
- Antibody-mediated degradation of 4R-tau restores mitochondrial membrane polarization in human induced pluripotent stem cell-derived neurons with the MAPT 10+16 mutation. (2024/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Natural History Characterization in Symptomatic and Asymptomatic Progranuline Gene Mutation Carriers (2024-12-24) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Skin as a Window to the Central Nervous System in Frontotemporal Lobar Degeneration (2024-12-20) ♡
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