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Diabetes with severe complications
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Publications and studies (3478)
- Kunkui Baoshen Granule attenuates diabetic kidney disease via the SIRT3/FOXO3a signaling pathway: An integrated multi-omics analysis. (2027/01/10) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. A randomized controlled trial of Kangfuxin Liquid for diabetic peripheral neuropathy. (2026/12/06) ♡
- Senkyunolide a from danggui buxue decoction protects podocytes against diabetic nephropathy via the mir-223-3p/nlrp3 inflammasome axis. (2026/12/06) ♡
- Hirsutine mitigates high glucose-induced cell injury via autophagy activation and NRF2/GPX4-mediated ferroptosis inhibition. (2026/12/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Adherence to the Mediterranean diet and its effects on the onset and progression of diabetic nephropathy: a systematic review. (2026/12/01) ♡
- Integrative multi-omics analysis identifies VCAN and ESM1 as candidate cell-type-associated biomarkers of NET-related glomerular injury in diabetic kidney disease. (2026/12/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Calciphylaxis in chronic kidney disease: a systematic review of pathomechanisms and risk factors for calcific uremic arteriolopathy. (2026/12/01) ♡
- Lishui Xiaozhong granules protect against diabetic retinopathy by activating PINK1/parkin-mediated mitophagy and suppressing ferroptosis. (2026/10/28) ♡
- Acupuncture inhibits ferroptosis and epithelial-mesenchymal transition to attenuate proteinuria in diabetic kidney disease. (2026/10/01) ♡
- Metabolomics approach using UHPLC/QE-MS for the mechanism of He Xue Ming Mu tablets on non-proliferative diabetic retinopathy. (2026/10/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review). (2026/10/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Efficacy and safety of Mudan granules for treatment of diabetic peripheral neuropathy: a multicenter, double-blind, placebo-controlled, randomized, clinical trial. (2026/09/15) ♡
- Wumei Pill ameliorates cognitive dysfunction in diabetic encephalopathy via inhibiting astrocyte-derived chemokine-receptor mediated neuroinflammation. (2026/09/15) ♡
- Lycium barbarum glycopeptide alleviates diabetic retinopathy and hepatic lipid disorder via modulation of the LXR-α/ABC transporter axis. (2026/09/15) ♡
- Extracellular vesicle-encapsulated miRNAs mediate monocyte-endothelial cell crosstalk to exacerbate renal injury in diabetic kidney disease. (2026/09/15) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Liver Fat Changes in Patients With Type 2 Diabetes by Presence of Genetic Hepatic Steatosis: A Post Hoc Analysis of SURPASS-3 MRI. (2026/09/01) ♡
- Ameliorative effects of Wiryeongtang (herbal medicine) on cardiorenal complications via modulation of inflammatory and fibrotic responses in diabetic mice. (2026/09/01) ♡
- A Gut-Protective TRPV1-Neuroepithelial Axis: Electroacupuncture Reverses Intestinal Damage in Diet-Induced Obesity. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current advances and future perspectives of Astragalus membranaceus active components in regulating diabetic microvascular complications. (2026/09/01) ♡
- Di(2-Ethylhexyl) Phthalate Exposure and Risk of Diabetic Kidney Disease: Epidemiological Association and Mechanistic Insights. (2026/09/01) ♡
- Zhimu-Huangbo herb pair ameliorates diabetic cognitive impairment by modulating the CCL3-CCR5 axis-dependent interaction between neurons and CD8(+) T cells. (2026/09/01) ♡
- Coxsackievirus B Infections Are Associated With the Risk of Islet Autoimmunity in Children With Strong Genetic Susceptibility to Type 1 Diabetes-Results From the TRIGR Divia Study. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Beyond Glycemia in T1D: The Hidden Burden of Insulin Resistance and Cardiorenal Risk in Type 1 Diabetes-Part 1. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Beyond Glycemia in T1D: Insulin Resistance and Multiorgan Injury in Type 1 Diabetes-Part 2. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current State of Cardiorenal Disease in People with Type 1 Diabetes. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging Evidence for Cardiorenal Protection with Sodium-Glucose Cotransporter Inhibitors, Glucagon-like peptide-1 Receptor Agonists, and Mineralocorticoid Receptor Blockers in People with Type 1 Diabetes. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Type 5 Diabetes Mellitus: Pathophysiology, Clinical Phenotype, and Nutritional Management. (2026/09/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Neuropeptide Alterations in Type 2 Diabetes Mellitus: A Meta-Analysis of Circulating Spexin and Galanin Levels. (2026/09/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy of Vitamin C Treatment to Aid the Healing of Foot Ulcers in People With Diabetes: A Randomised, Placebo-Controlled Double-Blind Trial: The FOOT-C Study Protocol. (2026/09/01) ♡
- Fluorescence Lifetime Imaging Microscopy Detects Preeclampsia, Gestational Diabetes Mellitus, and Their Comorbidity Early by Profiling Lipid Dysregulation. (2026/08/11) ♡
- LncRNASNHG12 regulates the development of diabetic nephropathy through miR-129-5p/IL6ST axis. (2026/08/11) ♡
- Accelerated Brain Aging in Type 1 Diabetes Across Painful and Painless Peripheral Neuropathy: MRI-Based Brain Age Estimates From Deep Learning. (2026/08/11) ♡
- Cystatin C: Not Only a Kidney Marker but Also a Potential Early Indicator of Metabolic Alterations in Childhood Obesity. (2026/08/11) ♡
- [Expert consensus on the management of obesity in the elderly (2026 edition)]. (2026/08/11) ♡
- Over 25 Years of Simultaneous Pancreas Kidney Transplantation in New Zealand. (2026/08/10) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A 42-Year-Old Woman Presenting With Pheochromocytoma Multisystem Crisis Associated With Bilateral Pheochromocytomas Due to Multiple Endocrine Neoplasia Type 2A. (2026/08/10) ♡
- Beyond prevalence: A complete catchment eye health system profile using rapid assessment of avoidable blindness, a population-based eye health survey, and the first implementation of the newly developed health system module. (2026/08/10) ♡
- Proximal Tubular EZH2 Inhibits Diabetic Kidney Disease by Suppressing SHC1-Mediated Oxidative Stress. (2026/08/10) ♡
- Work stress, dietary patterns and metabolic syndrome among military personnel in Ghana: a cross-sectional study. (2026/08/10) ♡
- Tirzepatide Persistence and Associated Changes in Clinical Outcomes in US Adults With Obesity or Overweight: A 6-Month Claims Database Analysis. (2026/08/10) ♡
- Integrating serum pharmacochemistry and network pharmacology to elucidate the bioactive constituents and pharmacological mechanisms of Simiao Yong'an decoction in amelioration of insulin resistance in type 2 diabetes mellitus via PI3K/AKT pathway. (2026/08/10) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Glucagon-like peptide-1 receptor agonist-based regimens compared with metformin-based regimens for preventing cardiovascular disease in adults with type 2 diabetes mellitus. (2026/08/10) ♡
- Real-time visualization of hydrogen peroxide in cells and diabetic wounds using an activatable fluorescent probe. (2026/08/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Perioperative management of GLP-1 receptor agonists: a structured narrative review with considerations relevant to neurosurgical patients. (2026/08/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Type 2 Diabetes Mellitus and Chronic Venous Disease of the Lower Extremities: A Narrative Review. (2026/08/10) ♡
- A Modified Delphi consensus on early management of combined cardiovascular risk factors in adult patients with type 2 diabetes in Italy. (2026/08/10) ♡
- Peripheral blood cell counts as correlates of insulin sensitivity in children and youth with type 1 diabetes: A retrospective study from western India. (2026/08/10) ♡
- Common genetic variants in dyslipidemia, inflammation, and angiogenesis pathways associated with diabetic nephropathy in Tunisians. (2026/08/10) ♡
- Nicotinamide Mononucleotide Ameliorates Myocardial Fibrosis in Diabetic Mice Possibly by Modulating SIRT3 to Deacetylate GSK3β and Thereby Reducing the Phosphorylation of Smad3. (2026/08/10) ♡
- Clinical and Economic Burden of Autologous Skin Grafting for Nonthermal Full-Thickness Wounds Across Care Settings: A US Retrospective Claims Study. (2026/08/10) ♡
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