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Aplastic anemia

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the strongest evidence (23)Meta-analysis (7)Treatment guideline (3)Systematic review (6)Phase 3 study (5)Randomized trial (2)Clinical trial (526)Review article (173)Early study (phase 1 or 2) (29)Case report (219)Laboratory or animal study (25)Commentary or editorial (45)Retracted publication (2) Studies currently recruiting participants only (34)

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Publications and studies (1614)

• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Malnutrition from anorexia nervosa triggers severe complications of hereditary spherocytosis in an adolescent girl: A case report. (2022/06/03) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Single Nucleotide Polymorphisms in XMN1-HBG2, HBS1L-MYB, and BCL11A and Their Relation to High Fetal Hemoglobin Levels That Alleviate Anemia. (2022/06/02) ♡
• Fanconi anemia gene-associated germline predisposition in aplastic anemia and hematologic malignancies. (2022/06/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Severe aplastic anemia in a patient with erythropoietic protoporphyria successfully treated by avatrombopag. (2022/06/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Long-term follow-up of haploidentical transplantation in relapsed/refractory severe aplastic anemia: a multicenter prospective study. (2022/05/15) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Fanconi anemia and hematopoietic stem cell transplant as risk factors for oral squamous cell carcinoma: A case report with a 12-year follow-up. (2022/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The structure, function, and clinical use of the thrombopoietin receptor agonist avatrombopag. (2022/05/01) ♡
• Integrated Network Pharmacology and Metabolomics Analysis to Reveal the Potential Mechanism of Siwu Paste on Aplastic Anemia Induced by Chemotherapy Drugs. (2022/04/28) ♡
• Allogeneic Hematopoietic Stem Cell Transplantation in Severe Aplastic Anemia: A Single Centre Experience in Malaysia. (2022/04/08) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. SARS-CoV-2 infection coincident with newly diagnosed severe aplastic anemia: A report of two cases. (2022/04/01) ♡
• Circulating Endothelial Progenitor Cells and Their Relation to Thrombosis in Paroxysmal Nocturnal Hemoglobinuria and Aplastic Anemia. (2022/04/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. (2022/03/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A new frontier in Fanconi anemia: From DNA repair to ribosome biogenesis. (2022/03/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Ocular Manifestations in Patients with Fanconi Anemia: A Single-Center Experience Including 106 Patients. (2022/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A case of severe aplastic anaemia after SARS-CoV-2 vaccination. (2022/03/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Anemia and Idiopathic Intracranial Hypertension: A Systematic Review and Meta-analysis. (2022/03/01) ♡
• LincRNA-p21 promotes p21-mediated cell cycle arrest in benzene-induced hematotoxicity by sponging miRNA-17-5p. (2022/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Pancytopenia and thrombosis defects in zebrafish mutants of Fanconi anemia genes. (2022/03/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study. (2022/03/01) ♡
• In silico study of missense variants of FANCA, FANCC and FANCG genes reveals high risk deleterious alleles predisposing to Fanconi anemia pathogenesis. (2022/02/20) ♡
• Radiation-sparing reduced-intensity unrelated umbilical cord blood transplantation for rare hematological disorders in children. (2022/02/01) ♡
• Development and validation of a mortality predicting scoring system for severe aplastic anaemia patients receiving haploidentical allogeneic transplantation. (2022/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Alemtuzumab-induced red cell aplasia and other immune cytopenias: not so 'pure'. (2022/02/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Cancers after hematopoietic cell transplantation for aplastic anemia-the importance of persistence. (2022/02/01) ♡
• Infusion of haploidentical hematopoietic stem cells combined with mesenchymal stem cells for treatment of severe aplastic anemia in adult patients yields curative effects. (2022/02/01) ♡
• High Failure-Free Survival after Unrelated Donor Peripheral Blood Stem Cell Transplantation in Pediatric Severe Aplastic Anemia. (2022/02/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Novel conditioning regimen for upfront haploidentical hematopoietic cell transplantation in children with severe aplastic anemia and donor-specific anti-HLA antibodies. (2022/02/01) ♡
• Detection of cytogenetic changes and chromosomal aneuploidy with fluorescent in situ hybridization in cytological specimens of oral cancers in Fanconi anemia-Proof of concept. (2022/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Establishment of a Mouse Model of Acquired Aplastic Anemia Mediated by Cyclophosphamide Combined with Cyclosporine]. (2022/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Insights Into the Emergence of Paroxysmal Nocturnal Hemoglobinuria. (2022/01/28) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case Report: Successful Avatrombopag Treatment for Two Cases of Anti-PD-1 Antibody-Induced Acquired Amegakaryocytic Thrombocytopenia. (2022/01/27) ♡
• Measurement for the Area of Red Blood Cells From Microscopic Images Based on Image Processing Technology and Its Applications in Aplastic Anemia, Megaloblastic Anemia, and Myelodysplastic Syndrome. (2022/01/25) ♡
• Comparable Outcomes in Acquired Severe Aplastic Anemia Patients With Haploidentical Donor or Matched Related Donor Transplantation: A Retrospective Single-Center Experience. (2022/01/24) ♡
• Comparable Outcomes and Health-Related Quality of Life for Severe Aplastic Anemia: Haploidentical Combined With a Single Cord Blood Unit vs Matched Related Transplants. (2022/01/18) ♡
• Multi-Omics Profiling Identifies Pathways Associated With CD8(+) T-Cell Activation in Severe Aplastic Anemia. (2022/01/04) ♡
• Single-Cell RNA-Seq of Bone Marrow Cells in Aplastic Anemia. (2022/01/03) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A new step in understanding stem cell mobilization in patients with Fanconi anemia: A bridge to gene therapy. (2022/01/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia. (2022/01/01) ♡
• Global miRNA expression of bone marrow mesenchymal stem/stromal cells derived from Fanconi anemia patients. (2022/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Fanconi-like anemia related to a FANCM mutation. (2022/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Translational research for bone marrow failure patients. (2022/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening. (2022/01/01) ♡
• miR‑30a‑5p induces the adipogenic differentiation of bone marrow mesenchymal stem cells by targeting FAM13A/Wnt/β‑catenin signaling in aplastic anemia. (2022/01/01) ♡
• Risk of cancer in heterozygous relatives of patients with Fanconi anemia. (2022/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Severe aplastic anemia after COVID-19 mRNA vaccination: Causality or coincidence? (2022/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Hypoplastic myelodysplastic syndrome and acquired aplastic anemia: Immune-mediated bone marrow failure syndromes (Review). (2022/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current challenges of hematologic complications due to immune checkpoint blockade: a comprehensive review. (2022/01/01) ♡
• Antifungal Prophylaxis With Posaconazole in Immunocompromised Children Younger Than 13 Years. (2022/01/01) ♡
• Aplastic anemia: Quo vadis? (2022/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Use of Trifluoperazine in Transfusion Dependent DBA (2022-12-14) ♡

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