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Alzheimer's

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (155)Meta-analysis (36)Treatment guideline (1)Systematic review (60)Randomized trial (48)Phase 3 study (10)Clinical trial (630)Review article (742)Early study (phase 1 or 2) (19)Laboratory or animal research (221)Case description (17)Commentary or editorial (43)Retracted Publication (4) Studies currently seeking participants only (40)

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Publications and studies (3608)

• GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions. (2018/11/22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Body, Brain, Life for Cognitive Decline (BBL-CD): protocol for a multidomain dementia risk reduction randomized controlled trial for subjective cognitive decline and mild cognitive impairment. (2018/11/21) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Is a Meal without Wine Good for Health? (2018/11/16) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review. (2018/11/15) ♡
• SQYZ granules, a traditional Chinese herbal, attenuate cognitive deficits in AD transgenic mice by modulating on multiple pathogenesis processes. (2018/11/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Microglia in Alzheimer's Disease: Risk Factors and Inflammation. (2018/11/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gut microbiota in common elderly diseases affecting activities of daily living. (2018/11/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The hidden variables problem in Alzheimer's disease clinical trial design. (2018/11/13) ♡
• Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage. (2018/11/12) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Methanolic extract of Tamarix Gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats. (2018/11/12) ♡
• The Chinese herbal formula Fuzheng Quxie Decoction attenuates cognitive impairment and protects cerebrovascular function in SAMP8 mice. (2018/11/09) ♡
• Partial reduction of microglia does not affect tau pathology in aged mice. (2018/11/09) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Community-based supplementary feeding for food insecure, vulnerable and malnourished populations - an overview of systematic reviews. (2018/11/09) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sensorial frailty: age-related hearing loss and the risk of cognitive impairment and dementia in later life. (2018/11/09) ♡
• The Impact of the Virtual Cognitive Health Program on the Cognition and Mental Health of Older Adults: Pre-Post 12-Month Pilot Study. (2018/11/09) ♡
• Rosmarinic Acid Derivatives' Inhibition of Glycogen Synthase Kinase-3β Is the Pharmacological Basis of Kangen-Karyu in Alzheimer's Disease. (2018/11/08) ♡
• Broadband hyperspectral stimulated Raman scattering microscopy with a parabolic fiber amplifier source. (2018/11/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Functional Foods and Nutraceuticals as Dietary Intervention in Chronic Diseases; Novel Perspectives for Health Promotion and Disease Prevention. (2018/11/02) ♡
• Association of Retinal Nerve Fiber Layer Thickness With Brain Alterations in the Visual and Limbic Networks in Elderly Adults Without Dementia. (2018/11/02) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration. (2018/11/01) ♡
• Antimicrobial activity and phytochemical screening of Alpinia malaccensis (Ran-kiriya) against food-borne bacteria. (2018/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Phytochemical and Pharmacological Role of Liquiritigenin and Isoliquiritigenin From Radix Glycyrrhizae in Human Health and Disease Models. (2018/11/01) ♡
• [Pica]. (2018/11/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Frustrated Alzheimer's researchers seek better lab mice. (2018/11/01) ♡
• Sex and Gender Differences in Alzheimer's Disease Dementia. (2018/11/01) ♡
• The association between the serum 25-hydroxyvitamin D level and cardiovascular events in individuals with and without metabolic syndrome. (2018/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The protective effects of polyphenols on Alzheimer's disease: A systematic review. (2018/11/01) ♡
• Inflammaging. (2018/11/01) ♡
• Effects of Long-Term Treatment with a Blend of Highly Purified Olive Secoiridoids on Cognition and Brain ATP Levels in Aged NMRI Mice. (2018/10/30) ♡
• Procyanidins Extracted from Lotus Seedpod Ameliorate Amyloid-β-Induced Toxicity in Rat Pheochromocytoma Cells. (2018/10/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase. (2018/10/28) ♡
• Ninjinyoeito Improves Behavioral Abnormalities and Hippocampal Neurogenesis in the Corticosterone Model of Depression. (2018/10/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Progress of Researches on Mechanisms of Acupuncture Therapy in Regulating Brain Plasticity]. (2018/10/25) ♡
• Cannabis Therapeutics and the Future of Neurology. (2018/10/18) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sleep and circadian rhythm disruption and stress intersect in Alzheimer's disease. (2018/10/17) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. The integration site of the APP transgene in the J20 mouse model of Alzheimer's disease. (2018/10/10) ♡
• Active components, derived from Kai-xin-san, a herbal formula, increase the expressions of neurotrophic factor NGF and BDNF on mouse astrocyte primary cultures via cAMP-dependent signaling pathway. (2018/10/05) ♡
• Obesity and Alzheimer's disease, does the obesity paradox really exist? A magnetic resonance imaging study. (2018/10/05) ♡
• Chinese Herbal Medicine Glycyrrhiza inflata Reduces Aβ Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation. (2018/10/04) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Inhibition of protein misfolding and aggregation by natural phenolic compounds. (2018/10/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. High-frequency (50 Hz) electroacupuncture ameliorates cognitive impairment in rats with amyloid beta 1-42-induced Alzheimer's disease. (2018/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Diabetes and Alzheimer's Disease: Mechanisms and Nutritional Aspects. (2018/10/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. In Reply: The Preservation of Cognition 1 Year After Carotid Endarterectomy in Patients With Prior Cognitive Decline. (2018/10/01) ♡
• Estimation of Area Under the ROC Curve under nonignorable verification bias. (2018/10/01) ♡
• Beneficial effect of 6 weeks lasting handling of adult rats on spatial memory in experimental model of neurodegeneration. (2018/10/01) ♡
• The Situated Influence of Chronic Pain Perception on Chinese Older Adults' Self-Management in Home Care. (2018/09/28) ♡
• An Aqueous Extract of Herbal Medicine ALWPs Enhances Cognitive Performance and Inhibits LPS-Induced Neuroinflammation via FAK/NF-κB Signaling Pathways. (2018/09/26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study protocol for a randomised, double-blind, placebo-controlled 12-week pilot phase II trial of Sailuotong (SLT) for cognitive function in older adults with mild cognitive impairment. (2018/09/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The intestinal microbiome and Alzheimer's disease: A review. (2018/09/25) ♡
• Therapy of Dredging the Bowels Enhanced the Neuroprotective Effect of Nourishing Kidney Herbs on Hippocampal Cholinergic System in Alzheimer's Disease Model Rat Induced by Aβ 1-42. (2018/09/12) ♡

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